node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMD17330.1 | dcd | TL18_04400 | TL18_02905 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.661 |
AMD17330.1 | pyrG | TL18_04400 | TL18_05775 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.543 |
AMD17330.1 | pyrH | TL18_04400 | TL18_02825 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.489 |
AMD17330.1 | tmk | TL18_04400 | TL18_02260 | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
dcd | AMD17330.1 | TL18_02905 | TL18_04400 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.661 |
dcd | ndk | TL18_02905 | TL18_06095 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.930 |
dcd | pyrG | TL18_02905 | TL18_05775 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.930 |
ndk | dcd | TL18_06095 | TL18_02905 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.930 |
ndk | pyrG | TL18_06095 | TL18_05775 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.952 |
ndk | pyrH | TL18_06095 | TL18_02825 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.950 |
ndk | tmk | TL18_06095 | TL18_02260 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
pyrG | AMD17330.1 | TL18_05775 | TL18_04400 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.543 |
pyrG | dcd | TL18_05775 | TL18_02905 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.930 |
pyrG | ndk | TL18_05775 | TL18_06095 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.952 |
pyrG | pyrH | TL18_05775 | TL18_02825 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.758 |
pyrH | AMD17330.1 | TL18_02825 | TL18_04400 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.489 |
pyrH | ndk | TL18_02825 | TL18_06095 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.950 |
pyrH | pyrG | TL18_02825 | TL18_05775 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.758 |
pyrH | tmk | TL18_02825 | TL18_02260 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.486 |
tmk | AMD17330.1 | TL18_02260 | TL18_04400 | Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |