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| | rrmJ | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (210 aa) |
| | eif2b | Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (135 aa) |
| | tyrS | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa) |
| | tfb | Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (306 aa) |
| | AMD16935.1 | Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa) |
| | AMD16929.1 | ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | ef1B | Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa) |
| | AMD16862.1 | peptidyl-tRNA hydrolase; Catalyzes the hydrolysis of N-substituted aminoacyl-tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa) |
| | AMD16861.1 | ATPase; Originally found to be an inhibitor of the antiviral RNase-L in human cells; contains ABC-type nucleotide binding domains; putatively functions in RNA maturation; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (300 aa) |
| | AMD17004.1 | tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa) |
| | AMD17007.1 | Guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa) |
| | tiaS | DNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (424 aa) |
| | tfb-2 | Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (264 aa) |
| | AMD17062.1 | glycyl-tRNA synthetease; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa) |
| | AMD17065.1 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa) |
| | AMD17099.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa) |
| | AMD17105.1 | PBS lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa) |
| | AMD17124.1 | DNA modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa) |
| | AMD18434.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa) |
| | gatE | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (621 aa) |
| | gatD | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (436 aa) |
| | AMD17191.1 | 50S ribosomal protein L15e; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa) |
| | AMD17195.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa) |
| | AMD17196.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | AMD17253.1 | Deoxyhypusine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa) |
| | rpl37ae | 50S ribosomal protein L37; Binds to the 23S rRNA. (89 aa) |
| | AMD17268.1 | Ribonucleotide-diphosphate reductase subunit beta; Probably involved in the biogenesis of the ribosome. (161 aa) |
| | AMD17269.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa) |
| | AMD17277.1 | DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2445 aa) |
| | AMD17293.1 | seryl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa) |
| | AMD17307.1 | DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | AMD17387.1 | CAAX protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa) |
| | AMD17475.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (478 aa) |
| | cca | tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (454 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (663 aa) |
| | AMD17533.1 | Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa) |
| | hypA | Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (125 aa) |
| | rpl40e | 50S ribosomal protein L40; Contains a zinc-finger motif; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa) |
| | AMD17551.1 | Ribosome biogenesis protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (177 aa) |
| | AMD17560.1 | S-adenosyl-L-methionine-binding protein PYRAB06630; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa) |
| | AMD17563.1 | Flagellar protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa) |
| | AMD17588.1 | Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa) |
| | rpl37e | 50S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa) |
| | AMD17592.1 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the snRNP Sm proteins family. (76 aa) |
| | AMD17593.1 | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa) |
| | rps27ae | 30S ribosomal protein S27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS31 family. (50 aa) |
| | rps24e | 30S ribosomal protein S24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS24 family. (106 aa) |
| | AMD17621.1 | DNA-directed RNA polymerase subunit E; Participates in both the initiation and recycling phases of transcription; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa) |
| | eif2g | Translation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (404 aa) |
| | rps6e | 30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS6 family. (127 aa) |
| | infB | Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (596 aa) |
| | rpl24e | 50S ribosomal protein L24; Binds to the 23S rRNA. (53 aa) |
| | rps28e | 30S ribosomal protein S28; The function of S28E in the ribosome is unknown but the structure shows a variants OB-fold that is found in nucleic acid-binding proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa) |
| | rpl7ae | 50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (122 aa) |
| | AMD17630.1 | Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (365 aa) |
| | AMD17634.1 | Ribonuclease BN; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa) |
| | rnp2 | Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (118 aa) |
| | rnp3 | Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (236 aa) |
| | cysS | cysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (448 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (904 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (467 aa) |
| | thiI-2 | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (383 aa) |
| | AMD17720.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa) |
| | tgtA | 7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (659 aa) |
| | AMD17746.1 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa) |
| | AMD17779.1 | Hydrogenase expression protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa) |
| | rps8e | 30S ribosomal protein S8e; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa) |
| | pheS | phenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (514 aa) |
| | gltX | glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (556 aa) |
| | rps2 | 30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (200 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa) |
| | AMD17840.1 | DNA-directed RNA polymerase subunit N; Derived by automated computational analysis using gene prediction method: Protein Homology. (56 aa) |
| | rps9 | 30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (133 aa) |
| | rpl13 | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (141 aa) |
| | rpl18e | 50S ribosomal protein L18e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL18 family. (121 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (267 aa) |
| | rps11 | 30S ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rps4 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (179 aa) |
| | AMD16848.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | rps13 | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (149 aa) |
| | truB | H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (321 aa) |
| | AMD17851.1 | 50S ribosomal protein L14e; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa) |
| | rpl34e | 50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa) |
| | rpl15 | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa) |
| | rpl30p | 50S ribosomal protein L30; L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa) |
| | rps5 | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (213 aa) |
| | rpl18 | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa) |
| | rpl19e | 50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa) |
| | AMD17862.1 | 50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa) |
| | rpl6 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa) |
| | rps8 | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl5 | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (170 aa) |
| | rps4e | 30S ribosomal protein S4e; The function of this ribosomal subunit is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa) |
| | rpl24p | 50S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa) |
| | rpl14 | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rps17 | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (105 aa) |
| | rnp1 | Ribonuclease P protein component 1; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (92 aa) |
| | AMD17871.1 | Translation initiation factor Sui1; In yeast this protein is involved in start site selection during the initiation of translation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUI1 family. (112 aa) |
| | rpl29 | 50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (68 aa) |
| | rps3 | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (252 aa) |
| | rpl22 | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (154 aa) |
| | rps19p | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa) |
| | rpl2p | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (241 aa) |
| | rpl23 | 50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa) |
| | rpl4lp | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (254 aa) |
| | rpl3 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (336 aa) |
| | AMD17890.1 | Fibronectin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (668 aa) |
| | AMD17908.1 | Archaeosine tRNA-ribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa) |
| | AMD17914.1 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa) |
| | rps17e | 30S ribosomal protein S17e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS17 family. (65 aa) |
| | AMD17953.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa) |
| | AMD17955.1 | Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa) |
| | AMD17956.1 | Threonylcarbamoyladenosine tRNA methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa) |
| | AMD17957.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa) |
| | truA | Pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (289 aa) |
| | AMD17970.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | eif5a | Translation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (132 aa) |
| | AMD18075.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa) |
| | prf1 | Peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (414 aa) |
| | AMD18082.1 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa) |
| | rps10p | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | tuf | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa) |
| | fusA | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (732 aa) |
| | rps7 | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (186 aa) |
| | rps12 | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (141 aa) |
| | nusA | Transcription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. (143 aa) |
| | rpl30e | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (397 aa) |
| | AMD18094.1 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (921 aa) |
| | AMD18095.1 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (601 aa) |
| | AMD18096.1 | DNA-directed RNA polymerase subunit B'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (77 aa) |
| | taw1 | tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (305 aa) |
| | AMD18110.1 | tRNA (cytidine(56)-2'-O)-methyltransferase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (179 aa) |
| | AMD18113.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LarC family. (389 aa) |
| | AMD18478.1 | Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa) |
| | eif1a | Translation initiation factor IF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (101 aa) |
| | AMD18148.1 | Similar to yeast Dim2p protein that is essential for 40S ribosomal subunit; structural studies show binding to 3' end of 16S rRNA in complex with archaeal IF2 alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa) |
| | AMD18480.1 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa) |
| | rpl10e | 50S ribosomal protein L10e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL16 family. (162 aa) |
| | AMD18209.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa) |
| | trm1 | N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (390 aa) |
| | taw2 | SAM-dependent methyltransferase; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (242 aa) |
| | flpA | Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (213 aa) |
| | gatB | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (450 aa) |
| | AMD18275.1 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa) |
| | AMD18285.1 | TIM barrel oxidoreductase NifR3; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa) |
| | AMD18294.1 | Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa) |
| | nop10 | Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (55 aa) |
| | eif2a | Translation initiation factor IF-2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (266 aa) |
| | rps27e | 30S ribosomal protein S27; Derived by automated computational analysis using gene prediction method: Protein Homology. (59 aa) |
| | rpl44e | 50S ribosomal protein L44; Binds to the 23S rRNA. (92 aa) |
| | AMD18311.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa) |
| | truD | Pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (418 aa) |
| | leuS | leucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (951 aa) |
| | AMD18338.1 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa) |
| | hisS | histidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | rps15 | 30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa) |
| | AMD18355.1 | Serine/threonine protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (529 aa) |
| | thrS | threonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (608 aa) |
| | AMD18499.1 | LSM domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa) |
| | argS | arginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (566 aa) |
| | AMD18394.1 | Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa) |
| | aspC | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa) |
| | gatA | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (456 aa) |
| | AMD16577.1 | Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa) |
| | AMD16604.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1077 aa) |
| | AMD16668.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (107 aa) |
| | AMD16670.1 | DNA-directed RNA polymerase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa) |
| | csl4 | RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa) |
| | pus10 | Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (401 aa) |
| | rsmA | 16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (290 aa) |
| | AMD16701.1 | DNA-directed RNA polymerase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa) |
| | rpl21e | 50S ribosomal protein L21; Mediates an interaction between 5S and domains II and V of 23S; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa) |
| | lysS | lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (527 aa) |
| | tbp | Transcription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa) |
| | AMD16759.1 | GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa) |
| | rnp4 | Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (121 aa) |
| | AMD16764.1 | Ribosome assembly protein YhbY; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa) |
| | rpl39e | 50S ribosomal protein L39; Part of the polypeptide exit tunnel in the 50S ribosomal complex; Derived by automated computational analysis using gene prediction method: Protein Homology. (51 aa) |
| | rpl31e | 50S ribosomal protein L31; One of the proteins encircling the polypeptide exit tunnel in the ribozyme; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribosomal protein L31e family. (81 aa) |
| | eif6 | Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (224 aa) |
| | rpl18a | 50S ribosomal protein LX; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa) |
| | AMD16776.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa) |
| | AMD16792.1 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (137 aa) |
| | rtcB | tRNA-splicing ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (482 aa) |
| | rps3ae | 30S ribosomal protein S3Ae; The function for this protein is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS1 family. (193 aa) |
| | AMD16820.1 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa) |
| | AMD16823.1 | Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa) |
| | tfe | Transcription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] (172 aa) |
| | spt5 | Antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (156 aa) |
| | rpl11 | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (160 aa) |
| | rpl1 | 50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa) |
| | rplP0 | Acidic ribosomal protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (336 aa) |
| | rpl12p | 50S ribosomal protein L12; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (102 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (899 aa) |
| | thiI | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (384 aa) |
| | AMD16845.1 | Translation factor Sua5; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa) |
