STRINGSTRING
pelA pelA AMD16823.1 AMD16823.1 AMD18412.1 AMD18412.1 tfe tfe alaS alaS thiI thiI AMD16845.1 AMD16845.1 AMD16848.1 AMD16848.1 AMD16929.1 AMD16929.1 AMD16935.1 AMD16935.1 tfb tfb tyrS tyrS rrmJ rrmJ rnz rnz AMD17004.1 AMD17004.1 AMD17007.1 AMD17007.1 tiaS tiaS AMD17022.1 AMD17022.1 dnaG dnaG AMD17036.1 AMD17036.1 tfb-2 tfb-2 AMD17062.1 AMD17062.1 AMD17065.1 AMD17065.1 AMD17099.1 AMD17099.1 AMD17124.1 AMD17124.1 AMD18434.1 AMD18434.1 AMD17268.1 AMD17268.1 AMD17269.1 AMD17269.1 AMD17277.1 AMD17277.1 AMD17293.1 AMD17293.1 AMD17307.1 AMD17307.1 cas2 cas2 dtd dtd cca cca AMD17498.1 AMD17498.1 metG metG priL priL priS priS AMD17551.1 AMD17551.1 AMD17560.1 AMD17560.1 AMD17588.1 AMD17588.1 AMD17592.1 AMD17592.1 AMD17621.1 AMD17621.1 AMD17622.1 AMD17622.1 rpl7ae rpl7ae AMD17630.1 AMD17630.1 trpS trpS AMD17634.1 AMD17634.1 rrp42 rrp42 rrp41 rrp41 rrp4 rrp4 rnp2 rnp2 rnp3 rnp3 cysS cysS valS valS pheT pheT proS proS thiI-2 thiI-2 tgtA tgtA AMD17746.1 AMD17746.1 pheS pheS gltX gltX rnj rnj rpoK rpoK AMD17840.1 AMD17840.1 rpoD rpoD truB truB rnp1 rnp1 AMD17908.1 AMD17908.1 AMD17914.1 AMD17914.1 AMD17928.1 AMD17928.1 AMD17953.1 AMD17953.1 AMD17955.1 AMD17955.1 AMD17956.1 AMD17956.1 truA truA AMD17970.1 AMD17970.1 nusA nusA rpoA2 rpoA2 AMD18094.1 AMD18094.1 AMD18095.1 AMD18095.1 AMD18096.1 AMD18096.1 rpoH rpoH taw1 taw1 AMD18110.1 AMD18110.1 AMD18148.1 AMD18148.1 AMD18480.1 AMD18480.1 rnhB rnhB AMD18209.1 AMD18209.1 trm1 trm1 taw2 taw2 flpA flpA AMD18285.1 AMD18285.1 nop10 nop10 truD truD leuS leuS AMD18338.1 AMD18338.1 hisS hisS AMD18355.1 AMD18355.1 thrS thrS AMD18499.1 AMD18499.1 argS argS aspC aspC AMD18403.1 AMD18403.1 AMD16577.1 AMD16577.1 AMD16604.1 AMD16604.1 ileS ileS AMD16668.1 AMD16668.1 AMD16670.1 AMD16670.1 csl4 csl4 pus10 pus10 rsmA rsmA AMD16701.1 AMD16701.1 lysS lysS fen fen tbp tbp rnp4 rnp4 AMD16764.1 AMD16764.1 AMD16792.1 AMD16792.1 rtcB rtcB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pelAmRNA surveillance protein Pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (353 aa)
AMD16823.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
AMD18412.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
tfeTranscription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] (172 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (899 aa)
thiItRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (384 aa)
AMD16845.1Translation factor Sua5; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
AMD16848.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
AMD16929.1ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AMD16935.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (306 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa)
rrmJ23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (210 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (300 aa)
AMD17004.1tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AMD17007.1Guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
tiaSDNA-binding protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (424 aa)
AMD17022.1ATP synthase subunit H; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (414 aa)
AMD17036.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
tfb-2Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (264 aa)
AMD17062.1glycyl-tRNA synthetease; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
AMD17065.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
AMD17099.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
AMD17124.1DNA modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
AMD18434.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
AMD17268.1Ribonucleotide-diphosphate reductase subunit beta; Probably involved in the biogenesis of the ribosome. (161 aa)
AMD17269.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
AMD17277.1DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2445 aa)
AMD17293.1seryl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
AMD17307.1DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (91 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa)
ccatRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (454 aa)
AMD17498.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (663 aa)
priLDNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (442 aa)
priSDNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play [...] (325 aa)
AMD17551.1Ribosome biogenesis protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (177 aa)
AMD17560.1S-adenosyl-L-methionine-binding protein PYRAB06630; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
AMD17588.1Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
AMD17592.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the snRNP Sm proteins family. (76 aa)
AMD17621.1DNA-directed RNA polymerase subunit E; Participates in both the initiation and recycling phases of transcription; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
AMD17622.1PilT domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
rpl7ae50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (122 aa)
AMD17630.1Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (365 aa)
AMD17634.1Ribonuclease BN; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
rrp42RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (261 aa)
rrp41Exonuclease; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (231 aa)
rrp4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (306 aa)
rnp2Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (118 aa)
rnp3Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (236 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (448 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (904 aa)
pheTphenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (467 aa)
thiI-2tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (383 aa)
tgtA7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (659 aa)
AMD17746.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (514 aa)
gltXglutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (556 aa)
rnjRibonuclease J; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (447 aa)
rpoKDNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa)
AMD17840.1DNA-directed RNA polymerase subunit N; Derived by automated computational analysis using gene prediction method: Protein Homology. (56 aa)
rpoDDNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (267 aa)
truBH/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (321 aa)
rnp1Ribonuclease P protein component 1; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (92 aa)
AMD17908.1Archaeosine tRNA-ribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
AMD17914.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AMD17928.1Ribonuclease VapC; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
AMD17953.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
AMD17955.1Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
AMD17956.1Threonylcarbamoyladenosine tRNA methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
truAPseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (289 aa)
AMD17970.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
nusATranscription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. (143 aa)
rpoA2DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (397 aa)
AMD18094.1DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (921 aa)
AMD18095.1DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (601 aa)
AMD18096.1DNA-directed RNA polymerase subunit B'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
rpoHDNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (77 aa)
taw1tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (305 aa)
AMD18110.1tRNA (cytidine(56)-2'-O)-methyltransferase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (179 aa)
AMD18148.1Similar to yeast Dim2p protein that is essential for 40S ribosomal subunit; structural studies show binding to 3' end of 16S rRNA in complex with archaeal IF2 alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
AMD18480.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (204 aa)
AMD18209.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
trm1N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (390 aa)
taw2SAM-dependent methyltransferase; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (242 aa)
flpAFibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (213 aa)
AMD18285.1TIM barrel oxidoreductase NifR3; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
nop10Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (55 aa)
truDPseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (418 aa)
leuSleucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (951 aa)
AMD18338.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
hisShistidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa)
AMD18355.1Serine/threonine protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (529 aa)
thrSthreonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (608 aa)
AMD18499.1LSM domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (566 aa)
aspCaspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa)
AMD18403.1Metal-dependent phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
AMD16577.1Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
AMD16604.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1077 aa)
AMD16668.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (107 aa)
AMD16670.1DNA-directed RNA polymerase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
csl4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa)
pus10Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (401 aa)
rsmA16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (290 aa)
AMD16701.1DNA-directed RNA polymerase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
lysSlysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (527 aa)
fenFlap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (327 aa)
tbpTranscription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (181 aa)
rnp4Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (121 aa)
AMD16764.1Ribosome assembly protein YhbY; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
AMD16792.1Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (137 aa)
rtcBtRNA-splicing ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (482 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
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