STRINGSTRING
AMD18355.1 AMD18355.1 ribK ribK thiL thiL AMD16714.1 AMD16714.1 AMD16760.1 AMD16760.1 mptE mptE AMD16839.1 AMD16839.1 AMD18416.1 AMD18416.1 AMD16899.1 AMD16899.1 AMD16918.1 AMD16918.1 AMD16941.1 AMD16941.1 AMD16943.1 AMD16943.1 tmk tmk AMD16992.1 AMD16992.1 pyrH pyrH AMD17056.1 AMD17056.1 argB argB AMD17170.1 AMD17170.1 AMD17179.1 AMD17179.1 prs prs AMD17276.1 AMD17276.1 AMD17298.1 AMD17298.1 AMD17495.1 AMD17495.1 AMD17509.1 AMD17509.1 AMD17619.1 AMD17619.1 ndk ndk AMD17690.1 AMD17690.1 AMD17812.1 AMD17812.1 AMD17833.1 AMD17833.1 mvk mvk cmk cmk adkA adkA pgk2 pgk2 AMD17944.1 AMD17944.1 aroK aroK nadK nadK thiM thiM pgk pgk AMD18138.1 AMD18138.1 AMD18176.1 AMD18176.1 AMD18319.1 AMD18319.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMD18355.1Serine/threonine protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (529 aa)
ribKRiboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (124 aa)
thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (308 aa)
AMD16714.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (304 aa)
AMD16760.1ATPase AAA; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (181 aa)
mptE6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (239 aa)
AMD16839.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)
AMD18416.1Delta 1-pyrroline-5-carboxylate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
AMD16899.1Secretion protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
AMD16918.1Phosphoenolpyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (879 aa)
AMD16941.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
AMD16943.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
tmkThymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
AMD16992.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (225 aa)
AMD17056.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (287 aa)
AMD17170.1Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (311 aa)
AMD17179.1Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (304 aa)
AMD17276.1Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AMD17298.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AMD17495.1GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AMD17509.1Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AMD17619.1Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (169 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (150 aa)
AMD17690.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AMD17812.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (467 aa)
AMD17833.1Amino acid kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (266 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (320 aa)
cmkCytidylate kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
adkAAdenylate kinase; Catalyzes the formation of 2 ADP from AMP and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal adenylate kinase family. (186 aa)
pgk22-phosphoglycerate kinase; Catalyzes the formation of 2-phospho-D-glyceroyl phosphate from ATP and 2-phospho-D-glycerate; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AMD17944.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (406 aa)
aroKShikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
nadKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (619 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (288 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (404 aa)
AMD18138.1Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AMD18176.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (758 aa)
AMD18319.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
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