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AMD18152.1 AMD18152.1 srp54 srp54 AMD16759.1 AMD16759.1 AMD16760.1 AMD16760.1 ftsY ftsY AMD16815.1 AMD16815.1 ftsZ ftsZ AMD16927.1 AMD16927.1 pan pan uvrB uvrB uvrA uvrA AMD17250.1 AMD17250.1 AMD18444.1 AMD18444.1 AMD17482.1 AMD17482.1 AMD17533.1 AMD17533.1 rad50 rad50 eif2g eif2g infB infB AMD17636.1 AMD17636.1 AMD17693.1 AMD17693.1 AMD17937.1 AMD17937.1 AMD17950.1 AMD17950.1 AMD18084.1 AMD18084.1 tuf tuf fusA fusA AMD18157.1 AMD18157.1 AMD18493.1 AMD18493.1 AMD18332.1 AMD18332.1 rfc rfc rfcL rfcL AMD18354.1 AMD18354.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMD18152.1Copper ion-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
srp54Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (449 aa)
AMD16759.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
AMD16760.1ATPase AAA; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (181 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (506 aa)
AMD16815.1CdcH; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (378 aa)
AMD16927.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
panNucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome associa [...] (412 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (654 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (962 aa)
AMD17250.1Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (682 aa)
AMD18444.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AMD17482.1ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (325 aa)
AMD17533.1Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
rad50Recombinase RecF; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (915 aa)
eif2gTranslation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (404 aa)
infBTranslation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (596 aa)
AMD17636.1Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family. (546 aa)
AMD17693.1Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (715 aa)
AMD17937.1Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family. (536 aa)
AMD17950.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
AMD18084.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (809 aa)
tufElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa)
fusAElongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (732 aa)
AMD18157.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. (374 aa)
AMD18493.1ATPase P; Derived by automated computational analysis using gene prediction method: Protein Homology. (831 aa)
AMD18332.1Arsenic ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
rfcReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (315 aa)
rfcLATPase AAA; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (506 aa)
AMD18354.1Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (183 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
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