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| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa) |
| | AMD16563.1 | Citramalate synthase; Catalyzes condensation of pyruvate and acetyl-CoA to form (R)-citramalate; functions in isoleucine synthesis; belongs to the alpha-IPM synthetase/homocitrate synthase family; it is difficult distinguishing these proteins from enzymes in that family; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa) |
| | AMD16569.1 | Cobyrinic acid a,c-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa) |
| | sdhA | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (286 aa) |
| | pyrB | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa) |
| | AMD16606.1 | Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | leuD | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (159 aa) |
| | leuC | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (414 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. (423 aa) |
| | AMD16629.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1077 aa) |
| | hisF | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (274 aa) |
| | argD | Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (386 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (427 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (286 aa) |
| | lysS | lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (527 aa) |
| | AMD16742.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (451 aa) |
| | AMD16751.1 | UbiC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa) |
| | leuC-2 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (417 aa) |
| | aksA | Trans-homoaconitate synthase; In Methanococcus jannaschii this protein catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate; functions in alphaketosuberate synthesis which is a precursor in coenzyme B and biotin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa) |
| | AMD16756.1 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa) |
| | AMD16787.1 | Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa) |
| | AMD16788.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa) |
| | apgM | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (412 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa) |
| | AMD16816.1 | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (899 aa) |
| | AMD16855.1 | Biotin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa) |
| | AMD16913.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (445 aa) |
| | AMD16914.1 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | AMD16917.1 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (495 aa) |
| | AMD16918.1 | Phosphoenolpyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (879 aa) |
| | AMD16922.1 | 2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | porA | Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa) |
| | AMD18423.1 | Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa) |
| | AMD16924.1 | Pyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa) |
| | tyrS | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (320 aa) |
| | nadA | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (305 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1058 aa) |
| | AMD17003.1 | Lactaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (470 aa) |
| | AMD17004.1 | tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa) |
| | AMD17009.1 | D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (524 aa) |
| | AMD17016.1 | 2-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa) |
| | AMD17062.1 | glycyl-tRNA synthetease; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa) |
| | AMD17068.1 | Indolepyruvate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa) |
| | AMD17071.1 | phenylacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa) |
| | argJ | Ornithine acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (404 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (287 aa) |
| | AMD17104.1 | Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa) |
| | AMD17106.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa) |
| | AMD17115.1 | Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa) |
| | cimA | Citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. (489 aa) |
| | gatD | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (436 aa) |
| | AMD17147.1 | acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa) |
| | cobQ | Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (508 aa) |
| | AMD17251.1 | ATP phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa) |
| | AMD17264.1 | (4Fe-4S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa) |
| | AMD17272.1 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HisA/HisF family. (229 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (469 aa) |
| | AMD17293.1 | seryl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa) |
| | AMD17304.1 | phenylacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa) |
| | AMD17437.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa) |
| | AMD17460.1 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (323 aa) |
| | AMD17476.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (314 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (376 aa) |
| | aroA | Fructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (263 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (663 aa) |
| | AMD17517.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa) |
| | cpgS | 2,3-diphosphoglycerate synthetase; Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP. (459 aa) |
| | AMD17529.1 | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa) |
| | AMD17575.1 | Phosphoglycerate mutase; Catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa) |
| | AMD17576.1 | Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa) |
| | AMD17580.1 | Asparagine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa) |
| | metXA | MetX; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (488 aa) |
| | AMD17594.1 | Creatinine amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | AMD18455.1 | Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa) |
| | AMD17612.1 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa) |
| | argH | Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa) |
| | AMD17631.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (398 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (365 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (224 aa) |
| | AMD17668.1 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa) |
| | AMD17669.1 | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa) |
| | cysS | cysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (448 aa) |
| | AMD17672.1 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa) |
| | AMD17673.1 | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa) |
| | aroA-2 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (439 aa) |
| | AMD17678.1 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (904 aa) |
| | pheT | phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (467 aa) |
| | cofC | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (223 aa) |
| | AMD17699.1 | Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa) |
| | AMD17743.1 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa) |
| | glmS | Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (594 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (214 aa) |
| | AMD17759.1 | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa) |
| | AMD17771.1 | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa) |
| | AMD17785.1 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | pheS | phenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (514 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa) |
| | AMD17791.1 | Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa) |
| | AMD17799.1 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa) |
| | AMD17811.1 | F420-0--gamma-glutamyl ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa) |
| | AMD17812.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (467 aa) |
| | dapL | L,L-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (411 aa) |
| | gltX | glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (556 aa) |
| | AMD17829.1 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (414 aa) |
| | AMD17885.1 | Pyridoxal phosphate-dependent protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa) |
| | AMD17912.1 | 3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa) |
| | AMD17917.1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (309 aa) |
| | AMD17921.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa) |
| | AMD17935.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa) |
| | AMD17944.1 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (406 aa) |
| | AMD18469.1 | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa) |
| | aroK | Shikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | hacB | 3-isopropylmalate dehydratase; Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B; Belongs to the LeuD family. LeuD ty [...] (160 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (340 aa) |
| | pdaD | Pyruvoyl-dependent arginine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PdaD family. (153 aa) |
| | AMD18074.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa) |
| | AMD18078.1 | Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (444 aa) |
| | pgk | Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (404 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (222 aa) |
| | AMD18104.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa) |
| | cofD | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (301 aa) |
| | AMD18164.1 | Coenzyme F420:L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | mfnA | L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (385 aa) |
| | AMD18229.1 | Phosphopantothenoylcysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa) |
| | AMD18230.1 | Phosphopantothenoylcysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa) |
| | AMD18233.1 | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa) |
| | argG | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (392 aa) |
| | AMD18268.1 | Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa) |
| | AMD18270.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa) |
| | trpB-2 | Phosphoribosylanthranilate isomerase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) |
| | trpF | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (199 aa) |
| | AMD18306.1 | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (335 aa) |
| | AMD18308.1 | Anthranilate synthase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa) |
| | AMD18309.1 | Anthranilate synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa) |
| | AMD18315.1 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa) |
| | AMD18316.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0107 family. (129 aa) |
| | hisH | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (198 aa) |
| | leuS | leucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (951 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (283 aa) |
| | hisS | histidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (431 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (135 aa) |
| | AMD18351.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa) |
| | thrS | threonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (608 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (451 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa) |
| | AMD18383.1 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa) |
| | AMD18384.1 | Acetolactate synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa) |
| | AMD18387.1 | Ornithine carbamoyltransferase; Catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (302 aa) |
| | argS | arginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (566 aa) |
| | aspC | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (423 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (549 aa) |
