STRINGSTRING
AMD18230.1 AMD18230.1 AMD18231.1 AMD18231.1 AMD18234.1 AMD18234.1 AMD18235.1 AMD18235.1 queE queE AMD18237.1 AMD18237.1 AMD18241.1 AMD18241.1 AMD18245.1 AMD18245.1 AMD18259.1 AMD18259.1 cobB cobB nnrD nnrD hjc hjc AMD18270.1 AMD18270.1 AMD18277.1 AMD18277.1 dnaJ dnaJ AMD18286.1 AMD18286.1 AMD18289.1 AMD18289.1 AMD18290.1 AMD18290.1 AMD18292.1 AMD18292.1 rps27e rps27e rpl44e rpl44e trpD trpD AMD18309.1 AMD18309.1 AMD18493.1 AMD18493.1 AMD18496.1 AMD18496.1 nadE nadE htpX htpX hisI hisI AMD18354.1 AMD18354.1 AMD18355.1 AMD18355.1 thrS thrS surE-2 surE-2 ilvC ilvC AMD18382.1 AMD18382.1 AMD18384.1 AMD18384.1 purD purD aspC aspC hisD hisD ilvD ilvD AMD16558.1 AMD16558.1 AMD16571.1 AMD16571.1 ribK ribK dadD dadD hisG hisG AMD16594.1 AMD16594.1 cbiX cbiX thiL thiL AMD16606.1 AMD16606.1 leuC leuC AMD16626.1 AMD16626.1 AMD16627.1 AMD16627.1 ileS ileS purL purL AMD16638.1 AMD16638.1 AMD16639.1 AMD16639.1 AMD16660.1 AMD16660.1 AMD16668.1 AMD16668.1 csl4 csl4 AMD16672.1 AMD16672.1 AMD16708.1 AMD16708.1 thiC thiC AMD18407.1 AMD18407.1 AMD16725.1 AMD16725.1 moaA moaA AMD16729.1 AMD16729.1 AMD16738.1 AMD16738.1 fen fen leuC-2 leuC-2 AMD16756.1 AMD16756.1 topA topA AMD16758.1 AMD16758.1 rnp4 rnp4 AMD16778.1 AMD16778.1 AMD16784.1 AMD16784.1 AMD16788.1 AMD16788.1 mptE mptE AMD16792.1 AMD16792.1 rtcB rtcB apgM apgM glmM glmM AMD16802.1 AMD16802.1 AMD16807.1 AMD16807.1 AMD16809.1 AMD16809.1 lig lig thiC-2 thiC-2 pelA pelA AMD16820.1 AMD16820.1 AMD16822.1 AMD16822.1 AMD16827.1 AMD16827.1 alaS alaS fbp fbp AMD16844.1 AMD16844.1 AMD16852.1 AMD16852.1 AMD16855.1 AMD16855.1 AMD16858.1 AMD16858.1 AMD16863.1 AMD16863.1 AMD16904.1 AMD16904.1 AMD16917.1 AMD16917.1 AMD16918.1 AMD16918.1 AMD16919.1 AMD16919.1 AMD16922.1 AMD16922.1 AMD18423.1 AMD18423.1 AMD16931.1 AMD16931.1 AMD16935.1 AMD16935.1 tfb tfb purP purP AMD16963.1 AMD16963.1 nadA nadA rnz rnz carB carB AMD16975.1 AMD16975.1 AMD16978.1 AMD16978.1 AMD16983.1 AMD16983.1 AMD17007.1 AMD17007.1 AMD17008.1 AMD17008.1 AMD17010.1 AMD17010.1 AMD17018.1 AMD17018.1 AMD17031.1 AMD17031.1 dnaG dnaG tfb-2 tfb-2 AMD17042.1 AMD17042.1 AMD17055.1 AMD17055.1 AMD17067.1 AMD17067.1 AMD18429.1 AMD18429.1 AMD17089.1 AMD17089.1 AMD17101.1 AMD17101.1 AMD17104.1 AMD17104.1 AMD17106.1 AMD17106.1 AMD17113.1 AMD17113.1 AMD17115.1 AMD17115.1 AMD17120.1 AMD17120.1 AMD17127.1 AMD17127.1 AMD17146.1 AMD17146.1 AMD17147.1 AMD17147.1 AMD17166.1 AMD17166.1 AMD18435.1 AMD18435.1 upp upp AMD17224.1 AMD17224.1 prs prs uvrA uvrA AMD17248.1 AMD17248.1 guaB guaB rpl37ae rpl37ae purF purF AMD17287.1 AMD17287.1 AMD17299.1 AMD17299.1 AMD17300.1 AMD17300.1 AMD17307.1 AMD17307.1 AMD17309.1 AMD17309.1 AMD17315.1 AMD17315.1 AMD17316.1 AMD17316.1 AMD17326.1 AMD17326.1 AMD17327.1 AMD17327.1 AMD17349.1 AMD17349.1 AMD17350.1 AMD17350.1 AMD17379.1 AMD17379.1 AMD17380.1 AMD17380.1 cas2 cas2 cas1 cas1 surE surE AMD17458.1 AMD17458.1 AMD17468.1 AMD17468.1 AMD17482.1 AMD17482.1 cca cca AMD17497.1 AMD17497.1 metG metG AMD17505.1 AMD17505.1 priL priL priS priS cofH cofH AMD17511.1 AMD17511.1 AMD17512.1 AMD17512.1 AMD17514.1 AMD17514.1 AMD17516.1 AMD17516.1 AMD17519.1 AMD17519.1 uppS uppS AMD17529.1 AMD17529.1 AMD17533.1 AMD17533.1 hypA hypA AMD17537.1 AMD17537.1 AMD17540.1 AMD17540.1 rad50 rad50 AMD17548.1 AMD17548.1 AMD17549.1 AMD17549.1 AMD17551.1 AMD17551.1 AMD17561.1 AMD17561.1 pyrG pyrG AMD17575.1 AMD17575.1 rpl37e rpl37e AMD17594.1 AMD17594.1 AMD17596.1 AMD17596.1 AMD17597.1 AMD17597.1 AMD18456.1 AMD18456.1 rps27ae rps27ae spt4 spt4 AMD17622.1 AMD17622.1 eif2g eif2g ndk ndk rpl24e rpl24e AMD17635.1 AMD17635.1 mobA mobA AMD17663.1 AMD17663.1 AMD17664.1 AMD17664.1 AMD17666.1 AMD17666.1 AMD17667.1 AMD17667.1 AMD17668.1 AMD17668.1 cysS cysS pheT pheT AMD17682.1 AMD17682.1 egsA egsA AMD17699.1 AMD17699.1 tgtA tgtA AMD17774.1 AMD17774.1 AMD17775.1 AMD17775.1 AMD17779.1 AMD17779.1 AMD17786.1 AMD17786.1 pheS pheS AMD17789.1 AMD17789.1 AMD17793.1 AMD17793.1 AMD17811.1 AMD17811.1 AMD17812.1 AMD17812.1 purA purA AMD17820.1 AMD17820.1 hcp hcp AMD17830.1 AMD17830.1 rnj rnj fni fni mvk mvk eno eno rpoD rpoD AMD17848.1 AMD17848.1 AMD17883.1 AMD17883.1 AMD17898.1 AMD17898.1 AMD17901.1 AMD17901.1 AMD17907.1 AMD17907.1 AMD17909.1 AMD17909.1 AMD17910.1 AMD17910.1 AMD17918.1 AMD17918.1 AMD17919.1 AMD17919.1 AMD17928.1 AMD17928.1 pyrE pyrE AMD17935.1 AMD17935.1 AMD17953.1 AMD17953.1 AMD17956.1 AMD17956.1 AMD17959.1 AMD17959.1 AMD17962.1 AMD17962.1 AMD17980.1 AMD17980.1 AMD17987.1 AMD17987.1 pyrI pyrI AMD18040.1 AMD18040.1 AMD18050.1 AMD18050.1 AMD18051.1 AMD18051.1 AMD18056.1 AMD18056.1 nadK nadK mtrA mtrA AMD18081.1 AMD18081.1 AMD18095.1 AMD18095.1 thiM thiM thiE thiE taw1 taw1 sucC sucC AMD18105.1 AMD18105.1 AMD18113.1 AMD18113.1 queC queC AMD18116.1 AMD18116.1 ubiA ubiA AMD18478.1 AMD18478.1 AMD18132.1 AMD18132.1 AMD18141.1 AMD18141.1 top6A top6A AMD18151.1 AMD18151.1 AMD18154.1 AMD18154.1 cofD cofD AMD18164.1 AMD18164.1 rnhB rnhB AMD18176.1 AMD18176.1 pyrC pyrC AMD18181.1 AMD18181.1 AMD18182.1 AMD18182.1 AMD18184.1 AMD18184.1 mtrA-2 mtrA-2 AMD18197.1 AMD18197.1 AMD18202.1 AMD18202.1 AMD18205.1 AMD18205.1 mptA mptA cofG cofG AMD18224.1 AMD18224.1 AMD18229.1 AMD18229.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMD18230.1Phosphopantothenoylcysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
AMD18231.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
AMD18234.1Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AMD18235.1CBS domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
queERadical SAM protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (232 aa)
AMD18237.16-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
AMD18241.1Recombinase RecB; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (264 aa)
AMD18245.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
AMD18259.1Deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
cobBNAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (241 aa)
nnrDSugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of [...] (513 aa)
hjcHolliday junction resolvase; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. (135 aa)
AMD18270.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
AMD18277.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (746 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (380 aa)
AMD18286.1Metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
AMD18289.1Coenzyme F420-reducing hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AMD18290.1Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AMD18292.1Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (404 aa)
rps27e30S ribosomal protein S27; Derived by automated computational analysis using gene prediction method: Protein Homology. (59 aa)
rpl44e50S ribosomal protein L44; Binds to the 23S rRNA. (92 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (335 aa)
AMD18309.1Anthranilate synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
AMD18493.1ATPase P; Derived by automated computational analysis using gene prediction method: Protein Homology. (831 aa)
AMD18496.1Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (262 aa)
htpXPeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family. (321 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (135 aa)
AMD18354.1Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (183 aa)
AMD18355.1Serine/threonine protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (529 aa)
thrSthreonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (608 aa)
surE-2Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (258 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
AMD18382.1Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
AMD18384.1Acetolactate synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (436 aa)
aspCaspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (439 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (423 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (549 aa)
AMD16558.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
AMD16571.13,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (227 aa)
ribKRiboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (124 aa)
dadDN-ethylammeline chlorohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the [...] (434 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (286 aa)
AMD16594.1Sirohydrochlorin cobaltochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
cbiXSirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (165 aa)
thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (308 aa)
AMD16606.1Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
leuC3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (414 aa)
AMD16626.1Disulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (661 aa)
AMD16627.1Catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1077 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (712 aa)
AMD16638.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
AMD16639.1Lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AMD16660.1Competence protein TfoX; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
AMD16668.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (107 aa)
csl4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa)
AMD16672.1Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (334 aa)
AMD16708.1Cytosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (432 aa)
AMD18407.1Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
AMD16725.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
moaAMolybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (309 aa)
AMD16729.1Molybdopterin-guanine dinucleotide biosynthesis protein MobB; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AMD16738.1Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
fenFlap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (327 aa)
leuC-23-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (417 aa)
AMD16756.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (718 aa)
AMD16758.1Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (899 aa)
rnp4Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (121 aa)
AMD16778.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (302 aa)
AMD16784.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (510 aa)
AMD16788.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
mptE6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (239 aa)
AMD16792.1Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (137 aa)
rtcBtRNA-splicing ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (482 aa)
apgMPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (412 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa)
AMD16802.1Competence protein TfoX; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
AMD16807.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
AMD16809.1Phosphoglucomutase; Catalyzes the interconversion of alpha-D-mannose 1-phosphate to alpha-D-mannose 6-phosphate and alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphohexose mutase family. (454 aa)
ligDNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (552 aa)
thiC-2Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (424 aa)
pelAmRNA surveillance protein Pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (353 aa)
AMD16820.1Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
AMD16822.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
AMD16827.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (899 aa)
fbpFructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (365 aa)
AMD16844.1Phosphatidylglycerophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (189 aa)
AMD16852.1NIF3 family protein HcgD; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
AMD16855.1Biotin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
AMD16858.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AMD16863.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (53 aa)
AMD16904.1Iron transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
AMD16917.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (495 aa)
AMD16918.1Phosphoenolpyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (879 aa)
AMD16919.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AMD16922.12-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AMD18423.1Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)
AMD16931.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AMD16935.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (306 aa)
purP5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (363 aa)
AMD16963.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
nadAQuinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (305 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (300 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1058 aa)
AMD16975.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
AMD16978.1Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AMD16983.1Metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
AMD17007.1Guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AMD17008.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
AMD17010.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0145 family. (112 aa)
AMD17018.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
AMD17031.1ATP-dependent carboligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (414 aa)
tfb-2Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (264 aa)
AMD17042.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
AMD17055.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
AMD17067.1Indolepyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (630 aa)
AMD18429.1Molybdenum ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AMD17089.1Ribitol-5-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AMD17101.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
AMD17104.1Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
AMD17106.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
AMD17113.1Nickel-responsive regulator; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (154 aa)
AMD17115.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
AMD17120.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AMD17127.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AMD17146.1Ketoisovalerate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
AMD17147.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
AMD17166.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the complex I 49 kDa subunit family. (374 aa)
AMD18435.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
uppCatalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
AMD17224.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (304 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (962 aa)
AMD17248.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa)
rpl37ae50S ribosomal protein L37; Binds to the 23S rRNA. (89 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (469 aa)
AMD17287.1Nitrogenase iron protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NifH/BchL/ChlL family. (264 aa)
AMD17299.1NudC; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
AMD17300.1Ferritin; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
AMD17307.1DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
AMD17309.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (83 aa)
AMD17315.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
AMD17316.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
AMD17326.1Rubrerythrin; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
AMD17327.1Rubrerythrin; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
AMD17349.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
AMD17350.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AMD17379.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
AMD17380.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (91 aa)
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (331 aa)
surEHypothetical protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (271 aa)
AMD17458.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
AMD17468.1Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AMD17482.1ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (325 aa)
ccatRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (454 aa)
AMD17497.1Lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (663 aa)
AMD17505.1Isopropanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
priLDNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (442 aa)
priSDNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play [...] (325 aa)
cofHFO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (372 aa)
AMD17511.1Sulfopyruvate decarboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
AMD17512.1Sulfopyruvate decarboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
AMD17514.1Disulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (769 aa)
AMD17516.1Heterodisulfide reductase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AMD17519.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
uppSUDP diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (254 aa)
AMD17529.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AMD17533.1Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
hypAHydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (125 aa)
AMD17537.1Isopropanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
AMD17540.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
rad50Recombinase RecF; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (915 aa)
AMD17548.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
AMD17549.1Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (250 aa)
AMD17551.1Ribosome biogenesis protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (177 aa)
AMD17561.1Peptidase M42; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa)
AMD17575.1Phosphoglycerate mutase; Catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
rpl37e50S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (62 aa)
AMD17594.1Creatinine amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AMD17596.1Rubredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (36 aa)
AMD17597.1Rubredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (53 aa)
AMD18456.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
rps27ae30S ribosomal protein S27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS31 family. (50 aa)
spt4DNA-directed RNA polymerase subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (58 aa)
AMD17622.1PilT domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
eif2gTranslation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (404 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (150 aa)
rpl24e50S ribosomal protein L24; Binds to the 23S rRNA. (53 aa)
AMD17635.1DtxR family iron (metal) dependent repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (209 aa)
AMD17663.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AMD17664.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
AMD17666.1Desulfoferrodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
AMD17667.1Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
AMD17668.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (448 aa)
pheTphenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (552 aa)
AMD17682.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
egsAGlycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. (347 aa)
AMD17699.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
tgtA7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (659 aa)
AMD17774.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AMD17775.1CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (228 aa)
AMD17779.1Hydrogenase expression protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
AMD17786.1Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (514 aa)
AMD17789.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (333 aa)
AMD17793.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (698 aa)
AMD17811.1F420-0--gamma-glutamyl ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
AMD17812.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (467 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (339 aa)
AMD17820.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
hcpHydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (435 aa)
AMD17830.1Serralysin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (326 aa)
rnjRibonuclease J; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (447 aa)
fniIsopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (348 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (320 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (414 aa)
rpoDDNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (267 aa)
AMD17848.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AMD17883.1Pyruvate carboxylase subunit A; Catalyzes the ATP-dependent carboxylation of a covalently attached biotin and the transfer of the carboxyl group to pyruvate forming oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
AMD17898.1Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)
AMD17901.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
AMD17907.1Heterodisulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
AMD17909.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AMD17910.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AMD17918.1Inorganic pyrophosphatase; Catalyzes the hydrolysis of pyrophosphate to phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AMD17919.1Nitrogenase molybdenum-iron cofactor biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AMD17928.1Ribonuclease VapC; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (174 aa)
AMD17935.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
AMD17953.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
AMD17956.1Threonylcarbamoyladenosine tRNA methylthiotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
AMD17959.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
AMD17962.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
AMD17980.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (879 aa)
AMD17987.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
pyrIAspartate carbamoyltransferase; Involved in allosteric regulation of aspartate carbamoyltransferase. (159 aa)
AMD18040.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
AMD18050.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AMD18051.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AMD18056.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (288 aa)
nadKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (619 aa)
mtrAHypothetical protein; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (186 aa)
AMD18081.1Zinc-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
AMD18095.1DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (601 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (288 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (206 aa)
taw1tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (305 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (372 aa)
AMD18105.12-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
AMD18113.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LarC family. (389 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (225 aa)
AMD18116.1Peptidase M48; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ubiAPrenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (280 aa)
AMD18478.1Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
AMD18132.1Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (234 aa)
AMD18141.1Isopropanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
top6ADNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (364 aa)
AMD18151.1Metal-sensitive transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
AMD18154.1Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
cofDLPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (301 aa)
AMD18164.1Coenzyme F420:L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (204 aa)
AMD18176.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (758 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (418 aa)
AMD18181.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
AMD18182.1F420-nonreducing hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (475 aa)
AMD18184.1Methyl-viologen-reducing hydrogenase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
mtrA-2Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (238 aa)
AMD18197.1Methyl-coenzyme M reductase; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (551 aa)
AMD18202.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AMD18205.12-phosphosulfolactate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
mptAGTP cyclohydrolase; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (313 aa)
cofGFO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (363 aa)
AMD18224.1Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AMD18229.1Phosphopantothenoylcysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
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