STRINGSTRING
ade ade deoC deoC AMD17935.1 AMD17935.1 AMD17934.1 AMD17934.1 AMD17933.1 AMD17933.1 AMD17921.1 AMD17921.1 AMD17912.1 AMD17912.1 AMD17891.1 AMD17891.1 rnj rnj AMD17743.1 AMD17743.1 AMD17732.1 AMD17732.1 AMD17699.1 AMD17699.1 psmA psmA rrp4 rrp4 rrp41 rrp41 rrp42 rrp42 AMD17649.1 AMD17649.1 dtd dtd surE surE AMD18444.1 AMD18444.1 AMD17352.1 AMD17352.1 AMD17304.1 AMD17304.1 AMD17299.1 AMD17299.1 AMD17071.1 AMD17071.1 AMD17022.1 AMD17022.1 AMD17003.1 AMD17003.1 AMD16932.1 AMD16932.1 AMD18412.1 AMD18412.1 pelA pelA fen fen polC polC csl4 csl4 polB polB AMD18230.1 AMD18230.1 AMD18268.1 AMD18268.1 AMD18315.1 AMD18315.1 AMD18316.1 AMD18316.1 AMD18351.1 AMD18351.1 AMD18354.1 AMD18354.1 surE-2 surE-2 AMD18229.1 AMD18229.1 rnhB rnhB pdaD pdaD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adeAdenine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (572 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (242 aa)
AMD17935.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
AMD17934.1Exodeoxyribonuclease VII small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa)
AMD17933.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
AMD17921.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AMD17912.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AMD17891.1Metal-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0173 family. (238 aa)
rnjRibonuclease J; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (447 aa)
AMD17743.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AMD17732.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
AMD17699.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
psmAProteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (259 aa)
rrp4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (306 aa)
rrp41Exonuclease; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (231 aa)
rrp42RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (261 aa)
AMD17649.1Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa)
surEHypothetical protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (271 aa)
AMD18444.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AMD17352.1Nucleotide pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
AMD17304.1phenylacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AMD17299.1NudC; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
AMD17071.1phenylacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AMD17022.1ATP synthase subunit H; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
AMD17003.1Lactaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (470 aa)
AMD16932.16-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AMD18412.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
pelAmRNA surveillance protein Pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (353 aa)
fenFlap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (327 aa)
polCDNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1099 aa)
csl4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (189 aa)
polBDNA polymerase II; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (556 aa)
AMD18230.1Phosphopantothenoylcysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
AMD18268.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
AMD18315.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
AMD18316.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0107 family. (129 aa)
AMD18351.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
AMD18354.1Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (183 aa)
surE-2Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (258 aa)
AMD18229.1Phosphopantothenoylcysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (204 aa)
pdaDPyruvoyl-dependent arginine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PdaD family. (153 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
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