STRINGSTRING
cobD cobD radA radA AMD16666.1 AMD16666.1 AMD16726.1 AMD16726.1 AMD16727.1 AMD16727.1 AMD16760.1 AMD16760.1 AMD16815.1 AMD16815.1 radB radB AMD16927.1 AMD16927.1 AMD16939.1 AMD16939.1 AMD16940.1 AMD16940.1 mutS2 mutS2 AMD16959.1 AMD16959.1 AMD17023.1 AMD17023.1 AMD17024.1 AMD17024.1 atpE atpE atpC atpC atpF atpF atpA atpA atpD atpD pan pan AMD17199.1 AMD17199.1 AMD17200.1 AMD17200.1 AMD17207.1 AMD17207.1 AMD17208.1 AMD17208.1 cobQ cobQ AMD17219.1 AMD17219.1 uvrB uvrB uvrA uvrA AMD17236.1 AMD17236.1 AMD17237.1 AMD17237.1 AMD17250.1 AMD17250.1 AMD17277.1 AMD17277.1 AMD17365.1 AMD17365.1 AMD18444.1 AMD18444.1 glnQ glnQ AMD17472.1 AMD17472.1 AMD17482.1 AMD17482.1 AMD17539.1 AMD17539.1 rad50 rad50 AMD17547.1 AMD17547.1 AMD17605.1 AMD17605.1 AMD17636.1 AMD17636.1 AMD17693.1 AMD17693.1 AMD17730.1 AMD17730.1 AMD17795.1 AMD17795.1 AMD17802.1 AMD17802.1 AMD17937.1 AMD17937.1 AMD17950.1 AMD17950.1 AMD18084.1 AMD18084.1 top6B top6B top6A top6A AMD18152.1 AMD18152.1 AMD18157.1 AMD18157.1 AMD18260.1 AMD18260.1 AMD18487.1 AMD18487.1 dnaK dnaK AMD18493.1 AMD18493.1 AMD18332.1 AMD18332.1 rfc rfc rfcL rfcL AMD18348.1 AMD18348.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (345 aa)
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (311 aa)
AMD16666.1ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)
AMD16726.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
AMD16727.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (593 aa)
AMD16760.1ATPase AAA; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (181 aa)
AMD16815.1CdcH; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
radBDNA repair protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (234 aa)
AMD16927.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AMD16939.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (534 aa)
AMD16940.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
mutS2DNA mismatch repair protein MutS; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (641 aa)
AMD16959.1ATP-dependent helicase; Hel112; monomeric form of the enzyme from Sulfolobus shows 3'-5' ATP-dependent helicase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa)
AMD17023.1ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family. (666 aa)
AMD17024.1ATP synthase subunit K; Produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase proteolipid subunit family. (161 aa)
atpEATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (203 aa)
atpCATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (384 aa)
atpFATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (105 aa)
atpAATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (580 aa)
atpDATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (228 aa)
panNucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome associa [...] (412 aa)
AMD17199.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
AMD17200.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
AMD17207.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
AMD17208.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (508 aa)
AMD17219.1Membrane bound Lon protease from Thermococcus kodakarensis shows ATP-dependent protease activity towards folded polypeptides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S16 family. (655 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (654 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (962 aa)
AMD17236.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (863 aa)
AMD17237.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
AMD17250.1Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (682 aa)
AMD17277.1DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2445 aa)
AMD17365.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1002 aa)
AMD18444.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
glnQSimilar to ATP-binding component of ABC transporters; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
AMD17472.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AMD17482.1ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (325 aa)
AMD17539.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
rad50Recombinase RecF; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (915 aa)
AMD17547.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
AMD17605.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (597 aa)
AMD17636.1Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family. (546 aa)
AMD17693.1Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (715 aa)
AMD17730.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AMD17795.1Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
AMD17802.1Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AMD17937.1Thermosome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TCP-1 chaperonin family. (536 aa)
AMD17950.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
AMD18084.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (809 aa)
top6BDNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (567 aa)
top6ADNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (364 aa)
AMD18152.1Copper ion-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
AMD18157.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. (374 aa)
AMD18260.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
AMD18487.1Teichoic acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone. (625 aa)
AMD18493.1ATPase P; Derived by automated computational analysis using gene prediction method: Protein Homology. (831 aa)
AMD18332.1Arsenic ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
rfcReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (315 aa)
rfcLATPase AAA; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (506 aa)
AMD18348.1Hef nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (773 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
Server load: low (14%) [HD]