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AMD18371.1 AMD18371.1 AMD17191.1 AMD17191.1 AMD17052.1 AMD17052.1 AMD17036.1 AMD17036.1 dnaG dnaG AMD16927.1 AMD16927.1 rpl12p rpl12p rplP0 rplP0 AMD16802.1 AMD16802.1 rps3ae rps3ae AMD16790.1 AMD16790.1 rpl31e rpl31e AMD16754.1 AMD16754.1 rpl21e rpl21e AMD16660.1 AMD16660.1 AMD16579.1 AMD16579.1 AMD16577.1 AMD16577.1 albA albA rps10p rps10p AMD18027.1 AMD18027.1 AMD18001.1 AMD18001.1 AMD17998.1 AMD17998.1 AMD17955.1 AMD17955.1 rps17e rps17e AMD17910.1 AMD17910.1 AMD17880.1 AMD17880.1 rps19p rps19p rps3 rps3 rpl29 rpl29 rps17 rps17 rps4e rps4e rpl6 rpl6 AMD17862.1 AMD17862.1 rpl19e rpl19e rpl18 rpl18 rps5 rps5 rpl34e rpl34e truB truB rps4 rps4 rps2 rps2 AMD18466.1 AMD18466.1 AMD17827.1 AMD17827.1 AMD17740.1 AMD17740.1 nth nth rfcL rfcL rfc rfc AMD18496.1 AMD18496.1 AMD18330.1 AMD18330.1 AMD18327.1 AMD18327.1 rpl44e rpl44e nop10 nop10 dnaJ dnaJ cobB cobB flpA flpA AMD18227.1 AMD18227.1 AMD18226.1 AMD18226.1 AMD18156.1 AMD18156.1 top6A top6A AMD18130.1 AMD18130.1 rpl30e rpl30e AMD17649.1 AMD17649.1 AMD17630.1 AMD17630.1 rps28e rps28e rpl24e rpl24e rps6e rps6e rps24e rps24e rpl40e rpl40e rad50 rad50 priS priS priL priL rpl37ae rpl37ae AMD17222.1 AMD17222.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMD18371.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AMD17191.150S ribosomal protein L15e; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AMD17052.1Adhesin; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
AMD17036.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (414 aa)
AMD16927.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
rpl12p50S ribosomal protein L12; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (102 aa)
rplP0Acidic ribosomal protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (336 aa)
AMD16802.1Competence protein TfoX; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
rps3ae30S ribosomal protein S3Ae; The function for this protein is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS1 family. (193 aa)
AMD16790.1ATPase AAA; Involved in regulation of DNA replication. (372 aa)
rpl31e50S ribosomal protein L31; One of the proteins encircling the polypeptide exit tunnel in the ribozyme; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribosomal protein L31e family. (81 aa)
AMD16754.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
rpl21e50S ribosomal protein L21; Mediates an interaction between 5S and domains II and V of 23S; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL21 family. (96 aa)
AMD16660.1Competence protein TfoX; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
AMD16579.1Cell division control protein Cdc6; Involved in regulation of DNA replication. (387 aa)
AMD16577.1Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
albADNA/RNA-binding protein albA; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (91 aa)
rps10p30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
AMD18027.1Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
AMD18001.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AMD17998.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AMD17955.1Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
rps17e30S ribosomal protein S17e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS17 family. (65 aa)
AMD17910.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AMD17880.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
rps19p30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa)
rps330S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (252 aa)
rpl2950S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (68 aa)
rps1730S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (105 aa)
rps4e30S ribosomal protein S4e; The function of this ribosomal subunit is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
rpl650S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
AMD17862.150S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
rpl19e50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa)
rpl1850S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (193 aa)
rps530S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (213 aa)
rpl34e50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL34 family. (88 aa)
truBH/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (321 aa)
rps430S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (179 aa)
rps230S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (200 aa)
AMD18466.1Crystallin; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
AMD17827.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AMD17740.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (214 aa)
rfcLATPase AAA; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (506 aa)
rfcReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (315 aa)
AMD18496.1Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
AMD18330.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (957 aa)
AMD18327.1Metallophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
rpl44e50S ribosomal protein L44; Binds to the 23S rRNA. (92 aa)
nop10Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (55 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (380 aa)
cobBNAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (241 aa)
flpAFibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (213 aa)
AMD18227.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
AMD18226.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
AMD18156.1Metallophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
top6ADNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (364 aa)
AMD18130.1Acetylneuraminic acid synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
rpl30e50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL30 family. (98 aa)
AMD17649.1Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AMD17630.1Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
rps28e30S ribosomal protein S28; The function of S28E in the ribosome is unknown but the structure shows a variants OB-fold that is found in nucleic acid-binding proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS28 family. (68 aa)
rpl24e50S ribosomal protein L24; Binds to the 23S rRNA. (53 aa)
rps6e30S ribosomal protein S6; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS6 family. (127 aa)
rps24e30S ribosomal protein S24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS24 family. (106 aa)
rpl40e50S ribosomal protein L40; Contains a zinc-finger motif; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa)
rad50Recombinase RecF; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (915 aa)
priSDNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play [...] (325 aa)
priLDNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (442 aa)
rpl37ae50S ribosomal protein L37; Binds to the 23S rRNA. (89 aa)
AMD17222.1ADP-ribosylglycohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
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