STRINGSTRING
AMD16569.1 AMD16569.1 AMD16579.1 AMD16579.1 radA radA AMD16648.1 AMD16648.1 AMD16666.1 AMD16666.1 srp54 srp54 AMD16720.1 AMD16720.1 AMD16726.1 AMD16726.1 AMD16727.1 AMD16727.1 AMD16729.1 AMD16729.1 AMD16759.1 AMD16759.1 AMD16760.1 AMD16760.1 ftsY ftsY AMD16790.1 AMD16790.1 AMD16815.1 AMD16815.1 AMD16842.1 AMD16842.1 radB radB AMD16861.1 AMD16861.1 AMD16865.1 AMD16865.1 AMD16878.1 AMD16878.1 AMD16899.1 AMD16899.1 AMD16903.1 AMD16903.1 AMD16906.1 AMD16906.1 AMD16927.1 AMD16927.1 AMD16939.1 AMD16939.1 AMD16940.1 AMD16940.1 mutS2 mutS2 tmk tmk AMD16952.1 AMD16952.1 AMD16959.1 AMD16959.1 atpA atpA atpB atpB AMD17056.1 AMD17056.1 AMD17057.1 AMD17057.1 AMD17075.1 AMD17075.1 pan pan AMD17199.1 AMD17199.1 AMD17200.1 AMD17200.1 AMD17207.1 AMD17207.1 AMD17208.1 AMD17208.1 AMD17211.1 AMD17211.1 cobQ cobQ AMD17219.1 AMD17219.1 uvrB uvrB uvrA uvrA AMD17236.1 AMD17236.1 AMD17237.1 AMD17237.1 cbiO cbiO AMD17277.1 AMD17277.1 AMD17280.1 AMD17280.1 AMD17287.1 AMD17287.1 AMD17361.1 AMD17361.1 AMD17365.1 AMD17365.1 AMD18444.1 AMD18444.1 glnQ glnQ AMD17414.1 AMD17414.1 AMD17482.1 AMD17482.1 AMD17509.1 AMD17509.1 AMD17533.1 AMD17533.1 AMD17539.1 AMD17539.1 rad50 rad50 AMD17547.1 AMD17547.1 AMD17567.1 AMD17567.1 pyrG pyrG AMD17583.1 AMD17583.1 AMD17605.1 AMD17605.1 eif2g eif2g infB infB AMD17691.1 AMD17691.1 AMD17731.1 AMD17731.1 purA purA cmk cmk adkA adkA pgk2 pgk2 AMD17950.1 AMD17950.1 AMD17972.1 AMD17972.1 AMD17973.1 AMD17973.1 AMD17977.1 AMD17977.1 AMD17978.1 AMD17978.1 AMD17990.1 AMD17990.1 AMD17998.1 AMD17998.1 AMD18472.1 AMD18472.1 tuf tuf fusA fusA AMD18157.1 AMD18157.1 AMD18161.1 AMD18161.1 AMD18185.1 AMD18185.1 AMD18260.1 AMD18260.1 AMD18487.1 AMD18487.1 ychF ychF AMD18332.1 AMD18332.1 rfc rfc rfcL rfcL AMD18346.1 AMD18346.1 AMD18348.1 AMD18348.1 cbiA cbiA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMD16569.1Cobyrinic acid a,c-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
AMD16579.1Cell division control protein Cdc6; Involved in regulation of DNA replication. (387 aa)
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (311 aa)
AMD16648.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
AMD16666.1ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)
srp54Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (449 aa)
AMD16720.1Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AMD16726.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
AMD16727.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (593 aa)
AMD16729.1Molybdopterin-guanine dinucleotide biosynthesis protein MobB; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AMD16759.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
AMD16760.1ATPase AAA; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (181 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (506 aa)
AMD16790.1ATPase AAA; Involved in regulation of DNA replication. (372 aa)
AMD16815.1CdcH; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
AMD16842.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
radBDNA repair protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (234 aa)
AMD16861.1ATPase; Originally found to be an inhibitor of the antiviral RNase-L in human cells; contains ABC-type nucleotide binding domains; putatively functions in RNA maturation; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
AMD16865.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
AMD16878.1Type III restriction enzyme, res subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (895 aa)
AMD16899.1Secretion protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
AMD16903.1Iron transporter FeoB; Derived by automated computational analysis using gene prediction method: Protein Homology. (672 aa)
AMD16906.1ATP-binding protein; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (279 aa)
AMD16927.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AMD16939.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (534 aa)
AMD16940.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
mutS2DNA mismatch repair protein MutS; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (641 aa)
tmkThymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
AMD16952.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MCM family. (668 aa)
AMD16959.1ATP-dependent helicase; Hel112; monomeric form of the enzyme from Sulfolobus shows 3'-5' ATP-dependent helicase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (865 aa)
atpAATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (580 aa)
atpBATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (463 aa)
AMD17056.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AMD17057.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
AMD17075.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
panNucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome associa [...] (412 aa)
AMD17199.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
AMD17200.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
AMD17207.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
AMD17208.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
AMD17211.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (508 aa)
AMD17219.1Membrane bound Lon protease from Thermococcus kodakarensis shows ATP-dependent protease activity towards folded polypeptides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S16 family. (655 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (654 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (962 aa)
AMD17236.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (863 aa)
AMD17237.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
cbiOCobalt transporter ATP-binding subunit; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (277 aa)
AMD17277.1DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2445 aa)
AMD17280.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa)
AMD17287.1Nitrogenase iron protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NifH/BchL/ChlL family. (264 aa)
AMD17361.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1291 aa)
AMD17365.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1002 aa)
AMD18444.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
glnQSimilar to ATP-binding component of ABC transporters; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
AMD17414.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
AMD17482.1ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (325 aa)
AMD17509.1Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AMD17533.1Hydrogenase nickel incorporation protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AMD17539.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
rad50Recombinase RecF; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (915 aa)
AMD17547.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
AMD17567.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa)
AMD17583.1Multidrug ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AMD17605.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (597 aa)
eif2gTranslation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (404 aa)
infBTranslation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (596 aa)
AMD17691.1Nitrate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AMD17731.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (339 aa)
cmkCytidylate kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa)
adkAAdenylate kinase; Catalyzes the formation of 2 ADP from AMP and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal adenylate kinase family. (186 aa)
pgk22-phosphoglycerate kinase; Catalyzes the formation of 2-phospho-D-glyceroyl phosphate from ATP and 2-phospho-D-glycerate; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AMD17950.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
AMD17972.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
AMD17973.1Nickel ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AMD17977.1Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
AMD17978.1Nickel ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AMD17990.1Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
AMD17998.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AMD18472.1Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology. (944 aa)
tufElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa)
fusAElongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (732 aa)
AMD18157.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. (374 aa)
AMD18161.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
AMD18185.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AMD18260.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
AMD18487.1Teichoic acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
ychFTranslation-associated GTPase; The crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
AMD18332.1Arsenic ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
rfcReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (315 aa)
rfcLATPase AAA; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (506 aa)
AMD18346.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (614 aa)
AMD18348.1Hef nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (773 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (451 aa)
Your Current Organism:
Methanobrevibacter sp. YE315
NCBI taxonomy Id: 1609968
Other names: M. sp. YE315
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