(15 nodes) Innate Immune System network (Methanobrevibacter sp. YE315)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	psmA	Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (259 aa)
	AMD17789.1	Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (333 aa)
	deoC	Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (242 aa)
	tuf	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (413 aa)
	AMD18157.1	ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. (374 aa)
	psmB	Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (204 aa)
	hpt	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (189 aa)
	AMD17023.1	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family. (666 aa)
	atpE	ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (203 aa)
	atpC	ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (384 aa)
	atpF	ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (105 aa)
	atpA	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (580 aa)
	atpB	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (463 aa)
	atpD	ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (228 aa)
	AMD17293.1	seryl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)

Your Current Organism:

Methanobrevibacter sp. YE315

NCBI taxonomy Id: 1609968
Other names: M. sp. YE315

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMD17023.1	atpA	TL18_02680	TL18_02705	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	0.999
AMD17023.1	atpB	TL18_02680	TL18_02710	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	0.999
AMD17023.1	atpC	TL18_02680	TL18_02695	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.	ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
AMD17023.1	atpD	TL18_02680	TL18_02715	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.	ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
AMD17023.1	atpE	TL18_02680	TL18_02690	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.	ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
AMD17023.1	atpF	TL18_02680	TL18_02700	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.	ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
AMD17293.1	hpt	TL18_04200	TL18_00640	seryl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.	0.415
AMD17293.1	tuf	TL18_04200	TL18_08695	seryl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.577
AMD18157.1	tuf	TL18_09100	TL18_08695	ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.529
atpA	AMD17023.1	TL18_02705	TL18_02680	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.	0.999
atpA	atpB	TL18_02705	TL18_02710	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	0.999
atpA	atpC	TL18_02705	TL18_02695	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA	atpD	TL18_02705	TL18_02715	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA	atpE	TL18_02705	TL18_02690	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA	atpF	TL18_02705	TL18_02700	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpA	tuf	TL18_02705	TL18_08695	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.552
atpB	AMD17023.1	TL18_02710	TL18_02680	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	ATP synthase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase 116 kDa subunit family.	0.999
atpB	atpA	TL18_02710	TL18_02705	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.	0.999
atpB	atpC	TL18_02710	TL18_02695	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpB	atpD	TL18_02710	TL18_02715	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.	ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999