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| | AMD16626.1 | Disulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (661 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. (423 aa) |
| | AMD16716.1 | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa) |
| | AMD18407.1 | Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa) |
| | AMD16725.1 | Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa) |
| | AMD16731.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa) |
| | AMD16732.1 | tRNA CCA-pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa) |
| | AMD16733.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa) |
| | AMD16734.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa) |
| | AMD16735.1 | Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa) |
| | AMD16736.1 | Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa) |
| | AMD16737.1 | Protein fwdA; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa) |
| | AMD16738.1 | Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa) |
| | leuC-2 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (417 aa) |
| | aksA | Trans-homoaconitate synthase; In Methanococcus jannaschii this protein catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate; functions in alphaketosuberate synthesis which is a precursor in coenzyme B and biotin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa) |
| | AMD16756.1 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa) |
| | apgM | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (412 aa) |
| | fbp | Fructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (365 aa) |
| | AMD18415.1 | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reduction of methenyltetrahydromethanopterin to methylenetetrahydromethanopterin; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | AMD16856.1 | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reduction of methenyltetrahydromethanopterin to methylenetetrahydromethanopterin; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | AMD16858.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | AMD16859.1 | Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa) |
| | AMD16860.1 | Methyl-viologen-reducing hydrogenase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa) |
| | AMD18416.1 | Delta 1-pyrroline-5-carboxylate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa) |
| | AMD16914.1 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | AMD16915.1 | Tributyrin esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa) |
| | AMD16916.1 | Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa) |
| | AMD16917.1 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (495 aa) |
| | AMD16921.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa) |
| | AMD16922.1 | 2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | porA | Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa) |
| | AMD18423.1 | Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa) |
| | AMD16924.1 | Pyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa) |
| | mer | Methylene-tetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (318 aa) |
| | AMD17009.1 | D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (524 aa) |
| | AMD17035.1 | Dimethylmenaquinone methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa) |
| | AMD17104.1 | Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa) |
| | AMD17147.1 | acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa) |
| | AMD17169.1 | Formylmethanofuran--tetrahydromethanopterin formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | mfnB | Hypothetical protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (237 aa) |
| | AMD17280.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (568 aa) |
| | mch | N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (323 aa) |
| | AMD17460.1 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (323 aa) |
| | aroA | Fructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (263 aa) |
| | cofH | FO synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (372 aa) |
| | AMD17511.1 | Sulfopyruvate decarboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | AMD17512.1 | Sulfopyruvate decarboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa) |
| | AMD17514.1 | Disulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (769 aa) |
| | AMD17515.1 | Heterodisulfide reductase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | AMD17516.1 | Heterodisulfide reductase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa) |
| | AMD17518.1 | Phosphosulfolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa) |
| | AMD17575.1 | Phosphoglycerate mutase; Catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa) |
| | cofC | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (223 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (414 aa) |
| | AMD17895.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa) |
| | AMD17906.1 | Disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa) |
| | AMD17907.1 | Heterodisulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa) |
| | hacB | 3-isopropylmalate dehydratase; Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B; Belongs to the LeuD family. LeuD ty [...] (160 aa) |
| | AMD17961.1 | H4MPT-linked C1 transfer pathway protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa) |
| | AMD17962.1 | Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa) |
| | mtrA | Hypothetical protein; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (186 aa) |
| | AMD18161.1 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa) |
| | cofD | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (301 aa) |
| | AMD18164.1 | Coenzyme F420:L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | mfnA | L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (385 aa) |
| | AMD18176.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (758 aa) |
| | AMD18182.1 | F420-nonreducing hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (475 aa) |
| | AMD18183.1 | F420-nonreducing hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa) |
| | AMD18184.1 | Methyl-viologen-reducing hydrogenase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa) |
| | AMD18189.1 | Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of mtrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa) |
| | mtrG | Tetrahydromethanopterin S-methyltransferase subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (78 aa) |
| | AMD18191.1 | Tetrahydromethanopterin S-methyltransferase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa) |
| | mtrA-2 | Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (238 aa) |
| | mtrB | Tetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (109 aa) |
| | mtrC | Tetrahydromethanopterin S-methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (271 aa) |
| | mtrD | Tetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (230 aa) |
| | mtrE | Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (292 aa) |
| | AMD18197.1 | Methyl-coenzyme M reductase; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (551 aa) |
| | AMD18198.1 | Methyl-coenzyme M reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa) |
| | AMD18199.1 | Methyl-coenzyme M reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa) |
| | AMD18200.1 | Methyl-coenzyme M reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa) |
| | AMD18201.1 | Methyl-coenzyme M reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa) |
| | AMD18205.1 | 2-phosphosulfolactate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa) |
| | cofG | FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (363 aa) |
| | AMD18221.1 | Sulfolactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa) |
| | ftr | Formylmethanofuran--tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (295 aa) |
| | AMD18289.1 | Coenzyme F420-reducing hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa) |
| | AMD18290.1 | Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa) |
| | AMD18291.1 | Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa) |
| | AMD18292.1 | Coenzyme F420 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (404 aa) |
| | mtd | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (276 aa) |
| | fae-hps | Bifunctional formaldehyde-activating protein/3-hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (413 aa) |
