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| | sdhA | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa) |
| | AMD16626.1 | Disulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (661 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. (423 aa) |
| | AMD16716.1 | 6-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa) |
| | AMD18407.1 | Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa) |
| | AMD16725.1 | Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa) |
| | AMD16731.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa) |
| | AMD16732.1 | tRNA CCA-pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa) |
| | AMD16733.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa) |
| | AMD16734.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa) |
| | AMD16735.1 | Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa) |
| | AMD16736.1 | Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa) |
| | AMD16737.1 | Protein fwdA; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa) |
| | AMD16738.1 | Formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa) |
| | AMD16756.1 | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa) |
| | apgM | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (412 aa) |
| | AMD16819.1 | Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa) |
| | fbp | Fructose 1,6-bisphosphatase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (365 aa) |
| | AMD18415.1 | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reduction of methenyltetrahydromethanopterin to methylenetetrahydromethanopterin; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | AMD16856.1 | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reduction of methenyltetrahydromethanopterin to methylenetetrahydromethanopterin; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | AMD16858.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | AMD16859.1 | Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa) |
| | AMD16860.1 | Methyl-viologen-reducing hydrogenase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa) |
| | AMD16919.1 | Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa) |
| | AMD16921.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa) |
| | AMD16922.1 | 2-ketoisovalerate ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | porA | Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa) |
| | AMD18423.1 | Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa) |
| | AMD16924.1 | Pyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate to form acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa) |
| | mer | Methylene-tetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (318 aa) |
| | AMD17009.1 | D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (524 aa) |
| | AMD17018.1 | Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa) |
| | AMD17035.1 | Dimethylmenaquinone methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa) |
| | AMD17066.1 | Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (491 aa) |
| | AMD17147.1 | acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa) |
| | AMD17169.1 | Formylmethanofuran--tetrahydromethanopterin formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (304 aa) |
| | mch | N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (323 aa) |
| | AMD17437.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | AMD17460.1 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (323 aa) |
| | aroA | Fructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (263 aa) |
| | AMD17514.1 | Disulfide reductase; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (769 aa) |
| | AMD17515.1 | Heterodisulfide reductase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | AMD17516.1 | Heterodisulfide reductase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa) |
| | AMD17575.1 | Phosphoglycerate mutase; Catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa) |
| | sucD | Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (288 aa) |
| | AMD17672.1 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa) |
| | AMD17673.1 | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (228 aa) |
| | AMD17743.1 | acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa) |
| | AMD17812.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (467 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (414 aa) |
| | AMD17883.1 | Pyruvate carboxylase subunit A; Catalyzes the ATP-dependent carboxylation of a covalently attached biotin and the transfer of the carboxyl group to pyruvate forming oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa) |
| | AMD17887.1 | Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (173 aa) |
| | AMD17895.1 | Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa) |
| | AMD17906.1 | Disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa) |
| | AMD17907.1 | Heterodisulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa) |
| | mtrA | Hypothetical protein; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (186 aa) |
| | pgk | Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (404 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (222 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (372 aa) |
| | AMD18104.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | AMD18105.1 | 2-oxoglutarate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa) |
| | AMD18106.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa) |
| | AMD18107.1 | Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | AMD18120.1 | Pyruvate carboxylase subunit B; Catalyzes the formation of oxaloacetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (570 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa) |
| | AMD18176.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (758 aa) |
| | AMD18182.1 | F420-nonreducing hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (475 aa) |
| | AMD18183.1 | F420-nonreducing hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa) |
| | AMD18184.1 | Methyl-viologen-reducing hydrogenase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa) |
| | AMD18189.1 | Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of mtrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa) |
| | mtrG | Tetrahydromethanopterin S-methyltransferase subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (78 aa) |
| | AMD18191.1 | Tetrahydromethanopterin S-methyltransferase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa) |
| | mtrA-2 | Tetrahydromethanopterin S-methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (238 aa) |
| | mtrB | Tetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (109 aa) |
| | mtrC | Tetrahydromethanopterin S-methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (271 aa) |
| | mtrD | Tetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (230 aa) |
| | mtrE | Tetrahydromethanopterin S-methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (292 aa) |
| | AMD18197.1 | Methyl-coenzyme M reductase; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (551 aa) |
| | AMD18198.1 | Methyl-coenzyme M reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa) |
| | AMD18201.1 | Methyl-coenzyme M reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa) |
| | ftr | Formylmethanofuran--tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (295 aa) |
| | mtd | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (276 aa) |
| | fae-hps | Bifunctional formaldehyde-activating protein/3-hexulose-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (413 aa) |
