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glcB glcB HALO0328 HALO0328 HALO0338 HALO0338 HALO0340 HALO0340 HALO0683 HALO0683 HALO0684 HALO0684 HALO0685 HALO0685 HALO0762 HALO0762 HALO0763 HALO0763 HALO0764 HALO0764 HALO0948 HALO0948 HALO0985 HALO0985 HALO0986 HALO0986 ubiE ubiE HALO1101 HALO1101 HALO1104 HALO1104 HALO1107 HALO1107 HALO1375 HALO1375 HALO1376 HALO1376 HALO1377 HALO1377 mqo mqo HALO1702 HALO1702 HALO1721 HALO1721 HALO1724 HALO1724 HALO1791 HALO1791 HALO1854 HALO1854 HALO1855 HALO1855 HALO1977 HALO1977 HALO2106 HALO2106 nqrB nqrB nqrE nqrE HALO2211 HALO2211 fumC fumC HALO2256 HALO2256 HALO2275 HALO2275 HALO2276 HALO2276 HALO2289 HALO2289 HALO2291 HALO2291 HALO2471 HALO2471 HALO2711 HALO2711 HALO2834 HALO2834 ppc ppc HALO2879 HALO2879 HALO2942 HALO2942 HALO3031 HALO3031 HALO3033 HALO3033 mdh mdh HALO3345 HALO3345 sucD sucD sucC sucC HALO3398 HALO3398 HALO3399 HALO3399 HALO3400 HALO3400 HALO3401 HALO3401 HALO3402 HALO3402 HALO3403 HALO3403 HALO3567 HALO3567 HALO3658 HALO3658 HALO3686 HALO3686 HALO3893 HALO3893 aceK aceK HALO4228 HALO4228
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (724 aa)
HALO0328NADH dehydrogenase subunit L. (531 aa)
HALO0338Tetrathionate reductase subunit A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1031 aa)
HALO0340Tetrathionate reductase subunit B. (258 aa)
HALO0683Fumarate reductase, flavoprotein subunit. (595 aa)
HALO0684Fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa)
HALO0685Fumarate reductase subunit C. (133 aa)
HALO0762Molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (950 aa)
HALO0763Formate dehydrogenase iron-sulfur subunit. (204 aa)
HALO0764Formate dehydrogenase gamma subunit. (366 aa)
HALO0948Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (910 aa)
HALO0985Cytochrome d ubiquinol oxidase subunit 1. (523 aa)
HALO0986Cytochrome d ubiquinol oxidase subunit 2. (379 aa)
ubiEUbiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)
HALO1101Cbb3-type cytochrome c oxidase subunit; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (309 aa)
HALO1104Cytochrome c oxidase subunit 1; Belongs to the heme-copper respiratory oxidase family. (474 aa)
HALO1107Glycolate oxidase iron-sulfur subunit. (410 aa)
HALO1375NADH-quinone oxidoreductase subunit N. (496 aa)
HALO1376NADH-quinone oxidoreductase subunit N. (501 aa)
HALO1377Hydrogenase-4 component B. (590 aa)
mqoProbable malate:quinone oxidoreductase. (559 aa)
HALO1702High-potential iron-sulfur protein; Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria; Belongs to the high-potential iron-sulfur protein (HiPIP) family. (104 aa)
HALO1721Na(+)/H(+) antiporter subunit A. (784 aa)
HALO1724Na(+)/H(+) antiporter subunit D. (534 aa)
HALO1791Transglutaminase-like cysteine peptidase, predicted. (186 aa)
HALO1854Citrate synthase; Belongs to the citrate synthase family. (375 aa)
HALO1855Aconitate hydratase. (870 aa)
HALO1977Cytochrome c oxidase subunit 1; Belongs to the heme-copper respiratory oxidase family. (846 aa)
HALO2106Cytochrome b561. (177 aa)
nqrBNa(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (408 aa)
nqrENa(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (205 aa)
HALO2211Putative cytochrome b561. (190 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)
HALO2256Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. (867 aa)
HALO2275Cytochrome d ubiquinol oxidase subunit 1. (471 aa)
HALO2276Cytochrome d ubiquinol oxidase, subunit II. (333 aa)
HALO2289Cytochrome c oxidase, subunit I bacterial type; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (544 aa)
HALO2291Cytochrome c oxidase subunit 3. (286 aa)
HALO2471Putative Ni/Fe-hydrogenase B-type cytochrome subunit. (228 aa)
HALO2711Di-heme cytochrome, transmembrane. (189 aa)
HALO2834Menaquinone biosynthesis methyltransferase ubiE. (274 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (882 aa)
HALO2879Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (554 aa)
HALO2942Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (419 aa)
HALO3031NADH:ubiquinone/plastoquinone oxidoreductase. (946 aa)
HALO3033Putative K(+)/H(+) antiporter subunit D. (503 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (324 aa)
HALO3345Isocitrate dehydrogenase (NADP); Belongs to the monomeric-type IDH family. (744 aa)
sucDSuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCSuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
HALO33982-oxoglutarate dehydrogenase E1 component. (964 aa)
HALO3399Succinate dehydrogenase/fumarate reductase iron-sulfur prot. (236 aa)
HALO3400Succinate dehydrogenase/fumarate reductase, flavoprotein sub; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
HALO3401Succinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
HALO3402Succinate dehydrogenase cytochrome b556 subunit. (129 aa)
HALO3403Citrate synthase; Belongs to the citrate synthase family. (428 aa)
HALO3567Cytochrome o ubiquinol oxidase, subunit III. (203 aa)
HALO3658Cytochrome B561. (186 aa)
HALO3686Cytochrome protein 2. (185 aa)
HALO3893Putative uncharacterized protein. (414 aa)
aceKIsocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (586 aa)
HALO4228UPF0083 protein. (144 aa)
Your Current Organism:
Halomonas sp. R575
NCBI taxonomy Id: 1610576
Other names: H. sp. R57-5, Halomonas sp. R57-5
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