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HALO0185 HALO0185 HALO0186 HALO0186 ribA ribA HALO0316 HALO0316 HALO0317 HALO0317 HALO0369 HALO0369 HALO0370 HALO0370 HALO0371 HALO0371 HALO0372 HALO0372 HALO0373 HALO0373 HALO0420 HALO0420 HALO0610 HALO0610 HALO0611 HALO0611 HALO0612 HALO0612 HALO0613 HALO0613 HALO0620 HALO0620 HALO0728 HALO0728 luxS luxS HALO1508 HALO1508 HALO1575 HALO1575 HALO1576 HALO1576 HALO1577 HALO1577 potA potA HALO1621 HALO1621 HALO1835 HALO1835 HALO1883 HALO1883 HALO1924 HALO1924 HALO2010 HALO2010 HALO2093 HALO2093 HALO2094 HALO2094 HALO2095 HALO2095 HALO2096 HALO2096 HALO2115 HALO2115 HALO2116 HALO2116 HALO2117 HALO2117 HALO2118 HALO2118 HALO2119 HALO2119 HALO2336 HALO2336 fur fur HALO2679 HALO2679 HALO2720 HALO2720 HALO2721 HALO2721 HALO2822 HALO2822 HALO2823 HALO2823 HALO2824 HALO2824 HALO2825 HALO2825 HALO2826 HALO2826 HALO2838 HALO2838 HALO2839 HALO2839 HALO2860 HALO2860 secA secA hfq hfq HALO3098 HALO3098 HALO3153 HALO3153 HALO3243 HALO3243 HALO3244 HALO3244 HALO3245 HALO3245 HALO3246 HALO3246 HALO3247 HALO3247 HALO3274 HALO3274 HALO3281 HALO3281 HALO3282 HALO3282 HALO3358 HALO3358 HALO3359 HALO3359 HALO3360 HALO3360 HALO3361 HALO3361 ribA-2 ribA-2 HALO3482 HALO3482 HALO3747 HALO3747 HALO3899 HALO3899 HALO3900 HALO3900 HALO3901 HALO3901 HALO3902 HALO3902 HALO3920 HALO3920 HALO3921 HALO3921 HALO3922 HALO3922 HALO3923 HALO3923 yajC yajC HALO4001 HALO4001 HALO4003 HALO4003 HALO4004 HALO4004 HALO4005 HALO4005 HALO4006 HALO4006 HALO4007 HALO4007 HALO4041 HALO4041 ftsY ftsY HALO4101 HALO4101 HALO4102 HALO4102 HALO4103 HALO4103 HALO4104 HALO4104 ffh ffh HALO4205 HALO4205 HALO4289 HALO4289 HALO4290 HALO4290 HALO4291 HALO4291 secY secY secE secE HALO4399 HALO4399 HALO4400 HALO4400 HALO4401 HALO4401 HALO4402 HALO4402 HALO4422 HALO4422 flhC flhC flhD flhD secB secB yidC yidC HALO4574 HALO4574 HALO4575 HALO4575
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HALO0185Signal transduction response regulator, receiver domain. (220 aa)
HALO0186ATPase-like, ATP-binding domain. (470 aa)
ribAGTP cyclohydrolase-2-GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (211 aa)
HALO0316ATPase-like, ATP-binding domain. (435 aa)
HALO0317CheY-like superfamily. (225 aa)
HALO0369Extracellular ligand-binding receptor. (394 aa)
HALO0370ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family. (294 aa)
HALO0371ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family. (317 aa)
HALO0372ABC transporter ATP-binding protein. (238 aa)
HALO0373Branched-chain amino acid ABC transporter ATP-binding protein. (241 aa)
HALO0420Putative uncharacterized protein. (407 aa)
HALO0610Putative uncharacterized protein; Belongs to the ABC transporter superfamily. (552 aa)
HALO0611Binding-protein-dependent transport systems inner membrane component. (302 aa)
HALO0612Binding-protein-dependent transport systems inner membrane component. (318 aa)
HALO0613Bacterial extracellular solute-binding protein, family 5. (546 aa)
HALO0620(R)-3-hydroxydecanoyl-ACP:CoA transacylase. (281 aa)
HALO0728Phenazine biosynthesis PhzC/PhzF protein. (290 aa)
luxSAutoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (155 aa)
HALO1508Leu/Ile/Val-binding protein-like protein 2. (399 aa)
HALO1575ABC transporter permease. (262 aa)
HALO1576ABC transporter permease. (299 aa)
HALO1577ABC transporter substrate-binding protein. (351 aa)
potAABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (369 aa)
HALO1621Acyl-homoserine lactone synthase. (209 aa)
HALO1835Anthranilate synthase component II. (206 aa)
HALO1883AMP-dependent synthetase/ligase. (561 aa)
HALO1924ABC transporter substrate-binding protein. (417 aa)
HALO2010Two-component response regulator KdpE. (241 aa)
HALO2093Ferric transporter subunit ATP-binding component of ABC transporter CP4-6 prophage; Belongs to the ABC transporter superfamily. (360 aa)
HALO2094Spermidine/putrescine ABC transporter permease. (262 aa)
HALO2095Binding-protein-dependent transport systems inner membrane component. (266 aa)
HALO2096Bacterial extracellular solute-binding, family 1. (343 aa)
HALO2115Putative oligopeptide transport ATP-binding protein ykfD; Belongs to the ABC transporter superfamily. (353 aa)
HALO2116Oligopeptide transport ATP-binding protein oppD; Belongs to the ABC transporter superfamily. (338 aa)
HALO2117Binding-protein-dependent transport systems inner membrane component. (317 aa)
HALO2118Binding-protein-dependent transport systems inner membrane component. (349 aa)
HALO2119Bacterial extracellular solute-binding protein, family 5. (526 aa)
HALO2336AMP-dependent synthetase/ligase. (533 aa)
furZinc uptake regulation protein; Belongs to the Fur family. (146 aa)
HALO2679ATPase AAA. (341 aa)
HALO2720ATPase-like, ATP-binding domain. (456 aa)
HALO2721Transcriptional regulatory protein QseB. (220 aa)
HALO2822Branched-chain amino acid ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family. (330 aa)
HALO2823ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family. (295 aa)
HALO2824Putative uncharacterized protein. (407 aa)
HALO2825Branched-chain amino acid ABC transporter ATP-binding protein. (247 aa)
HALO2826High-affinity branched-chain amino acid transport ATP-binding protein BraF. (268 aa)
HALO2838ADC synthase. (473 aa)
HALO2839Anthranilate synthase, glutamine amidotransferase. (226 aa)
HALO2860Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (358 aa)
secAProtein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (910 aa)
hfqRNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (82 aa)
HALO3098Spermidine/putrescine import ATP-binding protein PotA; Belongs to the ABC transporter superfamily. (336 aa)
HALO3153Putative uncharacterized protein. (5646 aa)
HALO3243ABC transporter substrate binding protein. (380 aa)
HALO3244ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family. (306 aa)
HALO3245Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (358 aa)
HALO3246Putative branched-chain amino acid transport ATP-binding protein LivG. (250 aa)
HALO3247High-affinity branched-chain amino acid transport ATP-binding protein BraG. (226 aa)
HALO3274Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (388 aa)
HALO3281Sensor protein qseC. (439 aa)
HALO3282CheY-like superfamily. (233 aa)
HALO3358Protein XP55. (529 aa)
HALO3359Oligopeptide transport system permease protein AppB. (330 aa)
HALO3360Binding-protein-dependent transport systems inner membrane component. (272 aa)
HALO3361Oligopeptide transport ATP-binding protein oppD. (281 aa)
ribA-2GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (367 aa)
HALO3482Riboflavin biosynthesis protein ribD. (280 aa)
HALO3747ATPase-like, ATP-binding domain. (486 aa)
HALO3899Extracellular solute-binding protein. (518 aa)
HALO3900Oligopeptide ABC transporter. (326 aa)
HALO3901Binding-protein-dependent transport systems inner membrane component. (277 aa)
HALO3902ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (546 aa)
HALO3920ABC transporter related protein; Belongs to the ABC transporter superfamily. (555 aa)
HALO3921ABC-type transporter, integral membrane subunit. (297 aa)
HALO3922ABC-type transporter, integral membrane subunit. (313 aa)
HALO3923ABC transporter, substrate-binding protein. (536 aa)
yajCPreprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (108 aa)
HALO4001Putative uncharacterized protein. (507 aa)
HALO4003Extracellular solute-binding protein, family 5. (505 aa)
HALO4004Binding-protein-dependent transport systems inner membrane component. (305 aa)
HALO4005ABC-type dipeptide/oligopeptide/nickel transport system, permease component. (303 aa)
HALO4006Antimicrobial peptide transporter subunit ATP-binding component of ABC superfamily transporter; Belongs to the ABC transporter superfamily. (349 aa)
HALO4007Dipeptide transport ATP-binding protein DppF; Belongs to the ABC transporter superfamily. (337 aa)
HALO4041Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (341 aa)
ftsYSignal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (436 aa)
HALO4101Extracellular solute-binding protein. (526 aa)
HALO4102ABC transporter permease. (309 aa)
HALO4103Binding-protein-dependent transport systems inner membrane component. (292 aa)
HALO4104ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (537 aa)
ffhSignal recognition particle protein-Fifty-four homolog; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the [...] (475 aa)
HALO4205Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (119 aa)
HALO4289Binding-protein-dependent transport systems inner membrane component. (284 aa)
HALO4290Putative peptide transporter permease subunit: membrane component of ABC superfamily. (307 aa)
HALO4291Extracellular solute-binding protein. (509 aa)
secYProtein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (443 aa)
secEProtein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (127 aa)
HALO4399ABC transporter ATP-binding protein. (202 aa)
HALO4400ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family. (334 aa)
HALO4401High-affinity branched-chain amino acid transport system permease protein BraE; Belongs to the binding-protein-dependent transport system permease family. (441 aa)
HALO4402ABC transporter periplasmic protein. (402 aa)
HALO4422Putative uncharacterized protein. (4209 aa)
flhCFlagellar transcriptional regulator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (180 aa)
flhDFlagellar transcriptional regulator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (110 aa)
secBProtein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (166 aa)
yidCMembrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (562 aa)
HALO4574Sensor protein qseC. (462 aa)
HALO4575Signal transduction response regulator, receiver domain. (226 aa)
Your Current Organism:
Halomonas sp. R575
NCBI taxonomy Id: 1610576
Other names: H. sp. R57-5, Halomonas sp. R57-5
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