(82 nodes) Positive regulation of cell death network (Caenorhabditis nigoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cni-mtch-1	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (358 aa)
	Cni-M01E11.2	DUF1716 domain-containing protein. (543 aa)
	Cni-vha-10	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (126 aa)
	B9Z55_000750	SH3 domain-containing protein. (102 aa)
	B9Z55_000751	BAR domain-containing protein. (294 aa)
	B9Z55_000753	Uncharacterized protein. (264 aa)
	B9Z55_000586	Uncharacterized protein. (113 aa)
	B9Z55_000587	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (111 aa)
	B9Z55_000585	Uncharacterized protein. (120 aa)
	Cni-ces-2	BZIP domain-containing protein. (220 aa)
	Cni-eya-1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (504 aa)
	B9Z55_002818	Uncharacterized protein. (1059 aa)
	B9Z55_002823	Uncharacterized protein. (1085 aa)
	B9Z55_002817	Uncharacterized protein. (112 aa)
	B9Z55_002824	Uncharacterized protein. (553 aa)
	B9Z55_002654	Fork-head domain-containing protein. (250 aa)
	B9Z55_002655	Uncharacterized protein. (86 aa)
	B9Z55_002027	Ubiquitin-like domain-containing protein. (77 aa)
	Cni-wts-1	Uncharacterized protein. (898 aa)
	Cni-unc-11	ENTH domain-containing protein. (660 aa)
	Cni-hlh-2	BHLH domain-containing protein. (411 aa)
	B9Z55_001629	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (501 aa)
	Cni-D2005.3	Uncharacterized protein. (116 aa)
	Cni-C33F10.4	Uncharacterized protein. (344 aa)
	Cni-lgg-1	Protein lgg. (141 aa)
	Cni-toe-2	Uncharacterized protein. (645 aa)
	B9Z55_028686	PHD-type domain-containing protein. (239 aa)
	Cni-F21G4.6	Uncharacterized protein. (2022 aa)
	B9Z55_027719	Uncharacterized protein. (132 aa)
	Cni-unc-32	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (783 aa)
	B9Z55_027467	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (323 aa)
	Cni-sptf-3	Uncharacterized protein. (364 aa)
	B9Z55_024030	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (491 aa)
	Cni-dpy-23	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (475 aa)
	Cni-sym-3	C2 NT-type domain-containing protein. (322 aa)
	Cni-gei-15	Uncharacterized protein. (409 aa)
	B9Z55_024593	Uncharacterized protein. (563 aa)
	Cni-F41B4.1	Uncharacterized protein. (360 aa)
	Cni-dct-1	Uncharacterized protein. (230 aa)
	B9Z55_025798	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (571 aa)
	Cni-unc-3	IPT/TIG domain-containing protein. (485 aa)
	B9Z55_025797	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (598 aa)
	Cni-ceh-34	Homeobox domain-containing protein. (256 aa)
	Cni-eif-3.K	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (240 aa)
	Cni-rme-1	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (789 aa)
	Cni-dre-1	F-box domain-containing protein. (881 aa)
	B9Z55_019865	UBR-type domain-containing protein. (135 aa)
	B9Z55_019947	Uncharacterized protein. (1395 aa)
	Cni-unc-68	Uncharacterized protein. (3896 aa)
	Cni-egl-1	Uncharacterized protein. (113 aa)
	B9Z55_021754	Ubiquitin-like domain-containing protein. (77 aa)
	B9Z55_012065	Uncharacterized protein; Belongs to the peptidase C14A family. (449 aa)
	Cni-jnk-1	Mitogen-activated protein kinase. (494 aa)
	Cni-eel-1	Uncharacterized protein. (4147 aa)
	Cni-unc-26	SAC domain-containing protein. (1114 aa)
	Cni-ced-3	Uncharacterized protein; Belongs to the peptidase C14A family. (508 aa)
	Cni-pig-1	Non-specific serine/threonine protein kinase. (704 aa)
	B9Z55_014945	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (317 aa)
	B9Z55_015272	PRA1 family protein. (110 aa)
	B9Z55_015271	PRA1 family protein. (83 aa)
	B9Z55_016094	Uncharacterized protein; Belongs to the peptidase C14A family. (696 aa)
	B9Z55_016101	Uncharacterized protein; Belongs to the peptidase C14A family. (722 aa)
	B9Z55_016091	Uncharacterized protein; Belongs to the peptidase C14A family. (947 aa)
	B9Z55_016219	Uncharacterized protein; Belongs to the peptidase C14A family. (623 aa)
	Cni-ced-4	CARD domain-containing protein. (569 aa)
	Cni-ced-7	Uncharacterized protein. (1774 aa)
	Cni-dat-1	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (645 aa)
	B9Z55_011205	Uncharacterized protein. (176 aa)
	B9Z55_011200	Uncharacterized protein. (391 aa)
	Cni-tir-1	Uncharacterized protein. (585 aa)
	B9Z55_011211	SAM domain-containing protein. (350 aa)
	B9Z55_011614	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa)
	Cni-clp-1	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (832 aa)
	B9Z55_008854	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (837 aa)
	Cni-F42A10.5	Uncharacterized protein. (295 aa)
	Cni-rps-3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (271 aa)
	Cni-ced-6	PID domain-containing protein. (515 aa)
	Cni-unc-116	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (815 aa)
	Cni-unc-104	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1635 aa)
	B9Z55_005337	Uncharacterized protein. (233 aa)
	Cni-snt-1	Uncharacterized protein. (443 aa)
	Cni-hlh-3	BHLH domain-containing protein. (168 aa)

Your Current Organism:

Caenorhabditis nigoni

NCBI taxonomy Id: 1611254
Other names: C. nigoni, Caenorhabditis nigoni Felix, Braendle & Cutter, 2014, Caenorhabditis sp. 9 JU1325, Caenorhabditis sp. 9 JU1422, Caenorhabditis sp. 9 KK-2011, Caenorhabditis sp. 9 MAF-2010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B9Z55_000585	B9Z55_001629	A0A2G5VTV9	A0A2G5VGM0	Uncharacterized protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.990
B9Z55_000585	B9Z55_024030	A0A2G5VTV9	A0A2G5SSR6	Uncharacterized protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.990
B9Z55_000585	B9Z55_027467	A0A2G5VTV9	A0A2G5SG87	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.926
B9Z55_000585	Cni-unc-32	A0A2G5VTV9	A0A2G5SFL0	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.926
B9Z55_000587	B9Z55_001629	A0A2G5VU77	A0A2G5VGM0	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.974
B9Z55_000587	B9Z55_024030	A0A2G5VU77	A0A2G5SSR6	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.974
B9Z55_000587	B9Z55_027467	A0A2G5VU77	A0A2G5SG87	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.926
B9Z55_000587	Cni-unc-32	A0A2G5VU77	A0A2G5SFL0	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.926
B9Z55_000750	B9Z55_002027	A0A2G5VV14	A0A2G5VIJ3	SH3 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.570
B9Z55_000750	B9Z55_008854	A0A2G5VV14	A0A2G5UPF4	SH3 domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.910
B9Z55_000750	B9Z55_021754	A0A2G5VV14	A0A2G5TTW9	SH3 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.570
B9Z55_000750	B9Z55_025797	A0A2G5VV14	A0A2G5T0N2	SH3 domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.910
B9Z55_000750	B9Z55_025798	A0A2G5VV14	A0A2G5T0D0	SH3 domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.910
B9Z55_000750	Cni-F21G4.6	A0A2G5VV14	A0A2G5SAN3	SH3 domain-containing protein.	Uncharacterized protein.	0.573
B9Z55_000750	Cni-ced-6	A0A2G5VV14	A0A2G5USG2	SH3 domain-containing protein.	PID domain-containing protein.	0.584
B9Z55_000750	Cni-dpy-23	A0A2G5VV14	A0A2G5ST85	SH3 domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.704
B9Z55_000750	Cni-snt-1	A0A2G5VV14	A0A2G5V0L2	SH3 domain-containing protein.	Uncharacterized protein.	0.837
B9Z55_000750	Cni-unc-104	A0A2G5VV14	A0A2G5UZZ9	SH3 domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.544
B9Z55_000750	Cni-unc-11	A0A2G5VV14	A0A2G5VHN7	SH3 domain-containing protein.	ENTH domain-containing protein.	0.851
B9Z55_000750	Cni-unc-26	A0A2G5VV14	A0A2G5U673	SH3 domain-containing protein.	SAC domain-containing protein.	0.956

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