(46 nodes) Negative regulation of locomotion network (Caenorhabditis nigoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cni-stn-1	Uncharacterized protein. (440 aa)
	Cni-ahr-1	PAS domain-containing protein. (456 aa)
	B9Z55_001500	Uncharacterized protein. (196 aa)
	Cni-smp-2	Sema domain-containing protein; Belongs to the semaphorin family. (654 aa)
	Cni-blmp-1	Uncharacterized protein. (799 aa)
	Cni-smp-1	Sema domain-containing protein; Belongs to the semaphorin family. (710 aa)
	B9Z55_023457	Tyrosine-protein kinase. (1211 aa)
	Cni-dgk-1	Uncharacterized protein. (628 aa)
	B9Z55_022214	DAGKc domain-containing protein. (352 aa)
	B9Z55_027467	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (323 aa)
	Cni-sym-3	C2 NT-type domain-containing protein. (322 aa)
	Cni-unc-32	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (783 aa)
	B9Z55_016167	Uncharacterized protein. (698 aa)
	Cni-dat-1	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (645 aa)
	B9Z55_018885	Uncharacterized protein. (265 aa)
	Cni-vab-8	Uncharacterized protein. (583 aa)
	B9Z55_018887	Uncharacterized protein. (598 aa)
	Cni-Y75B8A.11	Uncharacterized protein. (91 aa)
	Cni-pdr-1	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (391 aa)
	Cni-mig-39	Dimer_Tnp_hAT domain-containing protein. (1028 aa)
	Cni-swsn-7	Uncharacterized protein. (1248 aa)
	Cni-egl-20	Uncharacterized protein. (393 aa)
	Cni-srgp-1	Uncharacterized protein. (1024 aa)
	Cni-rap-3	Uncharacterized protein. (205 aa)
	Cni-rap-2	Uncharacterized protein. (214 aa)
	Cni-dop-2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (882 aa)
	Cni-F55H12.5	Uncharacterized protein. (356 aa)
	B9Z55_018939	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (517 aa)
	Cni-pde-4	PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (405 aa)
	Cni-gpb-1	WD_REPEATS_REGION domain-containing protein. (340 aa)
	B9Z55_016357	WD_REPEATS_REGION domain-containing protein. (386 aa)
	Cni-slt-1	Uncharacterized protein. (1387 aa)
	Cni-F41B4.1	Uncharacterized protein. (360 aa)
	Cni-gei-15	Uncharacterized protein. (409 aa)
	Cni-flp-7	Uncharacterized protein. (188 aa)
	B9Z55_015366	G_PROTEIN_RECEP_F1_2 domain-containing protein. (94 aa)
	B9Z55_023482	Paired domain-containing protein. (281 aa)
	Cni-npr-22	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (318 aa)
	B9Z55_015735	Homeobox domain-containing protein. (289 aa)
	Cni-rig-6	Uncharacterized protein. (962 aa)
	Cni-vab-3	Homeobox domain-containing protein. (319 aa)
	Cni-nol-1	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (714 aa)
	Cni-eat-16	Uncharacterized protein. (473 aa)
	B9Z55_015737	Uncharacterized protein. (381 aa)
	Cni-unc-40	Uncharacterized protein. (1408 aa)
	Cni-mab-20	Uncharacterized protein; Belongs to the semaphorin family. (745 aa)

Your Current Organism:

Caenorhabditis nigoni

NCBI taxonomy Id: 1611254
Other names: C. nigoni, Caenorhabditis nigoni Felix, Braendle & Cutter, 2014, Caenorhabditis sp. 9 JU1325, Caenorhabditis sp. 9 JU1422, Caenorhabditis sp. 9 KK-2011, Caenorhabditis sp. 9 MAF-2010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B9Z55_015366	Cni-flp-7	A0A2G5U9U6	A0A2G5SUC8	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.520
B9Z55_015366	Cni-gpb-1	A0A2G5U9U6	A0A2G5V1L9	G_PROTEIN_RECEP_F1_2 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.746
B9Z55_015737	B9Z55_023482	A0A2G5UC54	A0A2G5SQ40	Uncharacterized protein.	Paired domain-containing protein.	0.445
B9Z55_016357	B9Z55_023457	A0A2G5T471	A0A2G5SPS2	WD_REPEATS_REGION domain-containing protein.	Tyrosine-protein kinase.	0.468
B9Z55_016357	Cni-srgp-1	A0A2G5T471	A0A2G5U4H5	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.577
B9Z55_018939	Cni-vab-8	A0A2G5TH37	A0A2G5TG71	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.549
B9Z55_022214	Cni-dgk-1	A0A2G5SJ43	A0A2G5SJR6	DAGKc domain-containing protein.	Uncharacterized protein.	0.926
B9Z55_022214	Cni-eat-16	A0A2G5SJ43	A0A2G5VFV4	DAGKc domain-containing protein.	Uncharacterized protein.	0.661
B9Z55_023457	B9Z55_016357	A0A2G5SPS2	A0A2G5T471	Tyrosine-protein kinase.	WD_REPEATS_REGION domain-containing protein.	0.468
B9Z55_023457	Cni-F41B4.1	A0A2G5SPS2	A0A2G5SV91	Tyrosine-protein kinase.	Uncharacterized protein.	0.588
B9Z55_023457	Cni-eat-16	A0A2G5SPS2	A0A2G5VFV4	Tyrosine-protein kinase.	Uncharacterized protein.	0.534
B9Z55_023457	Cni-gei-15	A0A2G5SPS2	A0A2G5SUZ5	Tyrosine-protein kinase.	Uncharacterized protein.	0.588
B9Z55_023457	Cni-gpb-1	A0A2G5SPS2	A0A2G5V1L9	Tyrosine-protein kinase.	WD_REPEATS_REGION domain-containing protein.	0.447
B9Z55_023457	Cni-pdr-1	A0A2G5SPS2	A0A2G5UU14	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.685
B9Z55_023457	Cni-rap-2	A0A2G5SPS2	A0A2G5TML7	Tyrosine-protein kinase.	Uncharacterized protein.	0.444
B9Z55_023457	Cni-rap-3	A0A2G5SPS2	A0A2G5U400	Tyrosine-protein kinase.	Uncharacterized protein.	0.444
B9Z55_023457	Cni-slt-1	A0A2G5SPS2	A0A2G5T1C5	Tyrosine-protein kinase.	Uncharacterized protein.	0.882
B9Z55_023457	Cni-srgp-1	A0A2G5SPS2	A0A2G5U4H5	Tyrosine-protein kinase.	Uncharacterized protein.	0.805
B9Z55_023457	Cni-unc-40	A0A2G5SPS2	A0A2G5VVH4	Tyrosine-protein kinase.	Uncharacterized protein.	0.700
B9Z55_023482	B9Z55_015737	A0A2G5SQ40	A0A2G5UC54	Paired domain-containing protein.	Uncharacterized protein.	0.445

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