(95 nodes) Modulation of chemical synaptic transmission network (Caenorhabditis nigoni)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cni-kcc-2	Uncharacterized protein. (1105 aa)
	Cni-nca-2	Uncharacterized protein. (1790 aa)
	Cni-fsn-1	Uncharacterized protein. (362 aa)
	Cni-unc-32	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (783 aa)
	B9Z55_027467	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (323 aa)
	Cni-aex-3	UDENN domain-containing protein. (1408 aa)
	Cni-gbb-1	G_PROTEIN_RECEP_F3_4 domain-containing protein. (901 aa)
	Cni-mgl-1	G_PROTEIN_RECEP_F3_4 domain-containing protein. (1001 aa)
	Cni-slo-2	Uncharacterized protein. (1091 aa)
	B9Z55_023152	Uncharacterized protein. (195 aa)
	Cni-mig-15	Uncharacterized protein. (1079 aa)
	B9Z55_024030	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (491 aa)
	Cni-glit-1	COesterase domain-containing protein. (738 aa)
	Cni-C07A12.18	Uncharacterized protein. (141 aa)
	Cni-dnj-14	J domain-containing protein. (217 aa)
	Cni-glr-6	Uncharacterized protein. (844 aa)
	Cni-unc-10	Uncharacterized protein. (2198 aa)
	Cni-unc-18	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (590 aa)
	Cni-stg-2	Uncharacterized protein. (359 aa)
	Cni-pag-3	Uncharacterized protein. (341 aa)
	Cni-sssh-1	Uncharacterized protein. (156 aa)
	Cni-nlg-1	COesterase domain-containing protein. (749 aa)
	B9Z55_016769	ANF_receptor domain-containing protein. (433 aa)
	Cni-glr-5	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (550 aa)
	Cni-F36H9.7	Uncharacterized protein. (126 aa)
	Cni-egl-8	Phosphoinositide phospholipase C. (1510 aa)
	Cni-egl-3	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (652 aa)
	Cni-hpo-9	BTB domain-containing protein. (563 aa)
	Cni-gar-3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (584 aa)
	Cni-slo-1	Uncharacterized protein. (1120 aa)
	B9Z55_012148	Uncharacterized protein. (192 aa)
	B9Z55_012190	Uncharacterized protein. (452 aa)
	B9Z55_012952	Uncharacterized protein. (191 aa)
	Cni-rap-1	Uncharacterized protein. (223 aa)
	Cnig_chr_I.g94	Uncharacterized protein. (354 aa)
	B9Z55_000926	Uncharacterized protein. (159 aa)
	B9Z55_000912	ZZ-type domain-containing protein. (364 aa)
	B9Z55_000819	LLGL domain-containing protein. (484 aa)
	B9Z55_000817	Lgl_C domain-containing protein. (838 aa)
	B9Z55_000706	Dystrobrevin. (585 aa)
	Cni-egl-30	Uncharacterized protein. (430 aa)
	Cni-cpx-1	Uncharacterized protein. (143 aa)
	Cni-sol-2	Uncharacterized protein. (445 aa)
	Cni-unc-122	Olfactomedin-like domain-containing protein. (555 aa)
	B9Z55_003533	Calponin-homology (CH) domain-containing protein. (188 aa)
	Cni-dys-1	Uncharacterized protein. (3412 aa)
	Cni-unc-75	Uncharacterized protein. (515 aa)
	B9Z55_002654	Fork-head domain-containing protein. (250 aa)
	B9Z55_002655	Uncharacterized protein. (86 aa)
	Cni-mctp-1	Uncharacterized protein. (843 aa)
	B9Z55_002178	Neur_chan_LBD domain-containing protein. (167 aa)
	Cni-mef-2	MADS-box domain-containing protein. (348 aa)
	Cni-unc-29	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (379 aa)
	Cni-mgl-2	G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the bZIP family. (1229 aa)
	Cni-unc-73	Uncharacterized protein. (1639 aa)
	Cni-aex-1	C2 domain-containing protein. (965 aa)
	Cni-ric-19	AH domain-containing protein. (435 aa)
	Cni-sol-1	Uncharacterized protein. (596 aa)
	Cni-sue-1	Uncharacterized protein. (539 aa)
	Cni-glr-3	Uncharacterized protein. (799 aa)
	Cni-spd-5	Uncharacterized protein. (1212 aa)
	Cni-eat-16	Uncharacterized protein. (473 aa)
	Cni-C16C2.4	BSD domain-containing protein. (370 aa)
	Cni-abts-1	Anion exchange protein. (1160 aa)
	B9Z55_006288	Uncharacterized protein. (75 aa)
	Cni-rab-3	Uncharacterized protein. (219 aa)
	Cni-casy-1	Uncharacterized protein. (983 aa)
	Cni-F46C5.7	Uncharacterized protein. (199 aa)
	Cni-F46C5.4	Uncharacterized protein. (186 aa)
	B9Z55_005445	ANF_receptor domain-containing protein. (401 aa)
	Cni-glr-4	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (638 aa)
	Cni-snt-1	Uncharacterized protein. (443 aa)
	Cni-rpy-1	Uncharacterized protein. (803 aa)
	Cni-sphk-1	DAGKc domain-containing protein. (438 aa)
	Cni-mec-15	Uncharacterized protein. (643 aa)
	B9Z55_009500	Uncharacterized protein. (608 aa)
	Cni-ida-1	Uncharacterized protein. (774 aa)
	Cni-gar-2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (573 aa)
	Cni-pll-1	Phosphoinositide phospholipase C. (1081 aa)
	Cni-daf-2	Uncharacterized protein. (1954 aa)
	Cni-ina-1	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1149 aa)
	Cni-dgk-3	Diacylglycerol kinase. (796 aa)
	B9Z55_010414	Uncharacterized protein. (205 aa)
	B9Z55_010404	ANF_receptor domain-containing protein. (807 aa)
	B9Z55_010132	PDZ domain-containing protein. (363 aa)
	Cni-elks-1	Uncharacterized protein. (884 aa)
	Cni-unc-17	MFS domain-containing protein. (543 aa)
	Cni-egl-21	Peptidase_M14 domain-containing protein. (473 aa)
	Cni-ric-3	RIC3 domain-containing protein. (382 aa)
	Cni-F35H10.10	G_PROTEIN_RECEP_F3_4 domain-containing protein; Belongs to the G-protein coupled receptor 3 family. (1412 aa)
	Cni-gbb-2	G_PROTEIN_RECEP_F3_4 domain-containing protein. (804 aa)
	Cni-unc-26	SAC domain-containing protein. (1114 aa)
	Cni-mgl-3	G_PROTEIN_RECEP_F3_4 domain-containing protein. (1041 aa)
	Cni-unc-77	Uncharacterized protein. (1867 aa)
	Cni-snpn-1	Uncharacterized protein. (123 aa)

Your Current Organism:

Caenorhabditis nigoni

NCBI taxonomy Id: 1611254
Other names: C. nigoni, Caenorhabditis nigoni Felix, Braendle & Cutter, 2014, Caenorhabditis sp. 9 JU1325, Caenorhabditis sp. 9 JU1422, Caenorhabditis sp. 9 KK-2011, Caenorhabditis sp. 9 MAF-2010

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B9Z55_000706	B9Z55_003533	A0A2G5VV38	A0A2G5VRA3	Dystrobrevin.	Calponin-homology (CH) domain-containing protein.	0.714
B9Z55_000706	Cni-dys-1	A0A2G5VV38	A0A2G5VQQ7	Dystrobrevin.	Uncharacterized protein.	0.864
B9Z55_000706	Cni-slo-1	A0A2G5VV38	A0A2G5TTG7	Dystrobrevin.	Uncharacterized protein.	0.560
B9Z55_000817	B9Z55_000819	A0A2G5VVC8	A0A2G5VVD0	Lgl_C domain-containing protein.	LLGL domain-containing protein.	0.900
B9Z55_000817	B9Z55_012148	A0A2G5VVC8	A0A2G5TVX4	Lgl_C domain-containing protein.	Uncharacterized protein.	0.444
B9Z55_000817	B9Z55_012190	A0A2G5VVC8	A0A2G5TWL7	Lgl_C domain-containing protein.	Uncharacterized protein.	0.444
B9Z55_000817	Cni-daf-2	A0A2G5VVC8	A0A2G5UNT9	Lgl_C domain-containing protein.	Uncharacterized protein.	0.406
B9Z55_000817	Cni-unc-10	A0A2G5VVC8	A0A2G5SW33	Lgl_C domain-containing protein.	Uncharacterized protein.	0.580
B9Z55_000817	Cni-unc-18	A0A2G5VVC8	A0A2G5SWD6	Lgl_C domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.581
B9Z55_000819	B9Z55_000817	A0A2G5VVD0	A0A2G5VVC8	LLGL domain-containing protein.	Lgl_C domain-containing protein.	0.900
B9Z55_000819	B9Z55_012148	A0A2G5VVD0	A0A2G5TVX4	LLGL domain-containing protein.	Uncharacterized protein.	0.444
B9Z55_000819	B9Z55_012190	A0A2G5VVD0	A0A2G5TWL7	LLGL domain-containing protein.	Uncharacterized protein.	0.444
B9Z55_000819	Cni-daf-2	A0A2G5VVD0	A0A2G5UNT9	LLGL domain-containing protein.	Uncharacterized protein.	0.406
B9Z55_000819	Cni-unc-10	A0A2G5VVD0	A0A2G5SW33	LLGL domain-containing protein.	Uncharacterized protein.	0.580
B9Z55_000819	Cni-unc-18	A0A2G5VVD0	A0A2G5SWD6	LLGL domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.581
B9Z55_000912	B9Z55_003533	A0A2G5VVG2	A0A2G5VRA3	ZZ-type domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.714
B9Z55_000912	Cni-dys-1	A0A2G5VVG2	A0A2G5VQQ7	ZZ-type domain-containing protein.	Uncharacterized protein.	0.864
B9Z55_000912	Cni-slo-1	A0A2G5VVG2	A0A2G5TTG7	ZZ-type domain-containing protein.	Uncharacterized protein.	0.560
B9Z55_000926	B9Z55_003533	A0A2G5VVH7	A0A2G5VRA3	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.714
B9Z55_000926	Cni-dys-1	A0A2G5VVH7	A0A2G5VQQ7	Uncharacterized protein.	Uncharacterized protein.	0.797

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