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| | ALO40630.1 | Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (604 aa) |
| | ALO41541.1 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (410 aa) |
| | cysI | Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (572 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (246 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (759 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (359 aa) |
| | ALO41615.1 | Hypothetical protein; Pfam:pfam00425 chorismate binding enzyme. (408 aa) |
| | ALO41766.1 | L-serine deaminase I; Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa) |
| | ALO41767.1 | NUDIX domain-containing protein; Pfam:pfam00293 NUDIX domain. (186 aa) |
| | ALO41768.1 | Aminodeoxychorismate synthase subunit I; Pfam:pfam00425 chorismate binding enzyme. (450 aa) |
| | ALO41825.1 | Isoaspartyl peptidase; Pfam:pfam01112 Asparaginase. (342 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (215 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Pfam:pfam02769 AIR synthase related protein, C-terminal domain. (350 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (384 aa) |
| | ALO41978.1 | Aspartokinase; Pfam:pfam00696 Amino acid kinase family; Belongs to the aspartokinase family. (448 aa) |
| | ALO41989.1 | Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa) |
| | ALO42030.1 | Ferredoxin; Pfam:pfam00111 2Fe-2S iron-sulfur cluster binding domain. (90 aa) |
| | ALO42031.1 | Ribonucleotide-diphosphate reductase subunit beta; Pfam:pfam00268 Ribonucleotide reductase, small chain. (390 aa) |
| | ALO42032.1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (761 aa) |
| | ALO42033.1 | Phosphoglycolate phosphatase; Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. (214 aa) |
| | serC | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (359 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa) |
| | ALO42041.1 | Pfam:pfam06305 Protein of unknown function (DUF1049). (88 aa) |
| | ALO42042.1 | Tetratricopeptide repeat protein. (378 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (160 aa) |
| | purK | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (379 aa) |
| | ALO42163.1 | Pfam:pfam00710 Asparaginase. (336 aa) |
| | pyrD | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa) |
| | cysQ | 3',5' adenosine diphosphate 3' phosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (256 aa) |
| | ALO42316.1 | Pfam:pfam00733 Asparagine synthase. (553 aa) |
| | cysC | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (198 aa) |
| | ALO40711.1 | Sodium/sulfate symporter; Pfam:pfam02080 TrkA-C domain. (574 aa) |
| | ALO42332.1 | Cystathionine beta-lyase, bacterial; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. (389 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (471 aa) |
| | cysD | Sulfate adenylyltransferase subunit 2; Pfam:pfam01507 Phosphoadenosine phosphosulfate reductase family. (299 aa) |
| | ALO42358.1 | Anthranilate synthase component 1; Pfam:pfam00425 chorismate binding enzyme. (528 aa) |
| | ALO42359.1 | Anthranilate synthase subunit II; Pfam:pfam00117 Glutamine amidotransferase class-I. (196 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (334 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Pfam:pfam00218 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (455 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (181 aa) |
| | ALO42547.1 | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (877 aa) |
| | ALO42548.1 | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Pfam:pfam02574 Homocysteine S-methyltransferase. (351 aa) |
| | metAS | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (315 aa) |
| | cysS | Cysteine--tRNA ligase; Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. (459 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (508 aa) |
| | ALO42575.1 | Pfam:pfam02674 Colicin V production protein. (164 aa) |
| | ALO42576.1 | DedD protein; Pfam:pfam05036 Sporulation related domain. (225 aa) |
| | ALO42577.1 | Bifunctional: folylpolyglutamate synthase dihydrofolate synthase; Pfam:pfam08245 Mur ligase middle domain; Belongs to the folylpolyglutamate synthase family. (420 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (265 aa) |
| | ALO42580.1 | FimV N-terminal domain protein. (1912 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (283 aa) |
| | ALO42597.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Pfam:pfam01717 Cobalamin-independent synthase, Catalytic domain. (342 aa) |
| | dapD | Pfam:pfam14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal; Belongs to the transferase hexapeptide repeat family. (275 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (153 aa) |
| | ALO42843.1 | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (322 aa) |
| | carB | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. (1072 aa) |
| | carA | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. (377 aa) |
| | dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (266 aa) |
| | ALO42894.1 | Dihydroorotase; Pfam:pfam13147 Amidohydrolase. (457 aa) |
| | ALO42932.1 | Peptidase M20D, amidohydrolase; Pfam:pfam01546 Peptidase family M20/M25/M40. (435 aa) |
| | ALO42974.1 | Hypothetical protein. (84 aa) |
| | ALO42975.1 | Phosphoserine phosphatase; Pfam:pfam00702 haloacid dehalogenase-like hydrolase. (356 aa) |
| | ALO42976.1 | Smp protein; Pfam:pfam10144 Bacterial virulence factor hemolysin. (206 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (524 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (489 aa) |
| | ALO42987.1 | Pfam:pfam06426 Serine acetyltransferase, N-terminal. (273 aa) |
| | ALO42988.1 | Pfam:pfam00155 Aminotransferase class I and II. (396 aa) |
| | ALO42994.1 | Bifunctional chorismate mutase/prephenate dehydratase; Pfam:pfam00800 Prephenate dehydratase. (383 aa) |
| | ALO42995.1 | Chorismate mutase; Pfam:pfam02153 Prephenate dehydrogenase. (378 aa) |
| | ALO43016.1 | Methionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. (392 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (367 aa) |
| | ALO43067.1 | Methylenetetrahydrofolate reductase. (334 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa) |
| | ALO43175.1 | Threonine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (427 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (312 aa) |
| | ALO43177.1 | Bifunctional aspartokinase I/homoserine dehydrogenase I; Pfam:pfam00742 Homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (804 aa) |
| | metK | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa) |
| | ALO43227.1 | Pfam:pfam02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (338 aa) |
| | ALO43233.1 | Carboxypeptidase; Pfam:pfam00450 Serine carboxypeptidase. (501 aa) |
| | ALO43234.1 | Hypothetical protein. (179 aa) |
| | ALO43235.1 | Carbon-nitrogen ligase; Pfam:pfam01812 5-formyltetrahydrofolate cyclo-ligase family; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (201 aa) |
| | ALO43237.1 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (409 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (155 aa) |
| | ALO43261.1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (163 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH; Pfam:pfam01808 AICARFT/IMPCHase bienzyme. (528 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. (427 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (438 aa) |
| | ALO43329.1 | Glutamate decarboxylase; Pfam:pfam00282 Pyridoxal-dependent decarboxylase conserved domain. (541 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa) |
| | ALO43352.1 | Pfam:pfam03590 Aspartate-ammonia ligase. (331 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | argH | Pfam:pfam00206 Lyase. (459 aa) |
| | argG | Pfam:pfam00764 Arginosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa) |
| | ALO43423.1 | Pfam:pfam02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain. (306 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (257 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (338 aa) |
| | ALO43426.1 | Acetylornithine deacetylase; Pfam:pfam01546 Peptidase family M20/M25/M40. (389 aa) |
| | ALO43433.1 | 3-mercaptopyruvate sulfurtransferase; Pfam:pfam00581 Rhodanese-like domain. (277 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Pfam:pfam01259 SAICAR synthetase. (366 aa) |
| | argD | Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (403 aa) |
| | ALO43472.1 | Pfam:pfam00117 Glutamine amidotransferase class-I. (195 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (356 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa) |
| | ALO43488.1 | Bifunctional aspartate kinase II/homoserine dehydrogenase II; Pfam:pfam00742 Homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (782 aa) |
| | ALO43489.1 | Cystathionine gamma-synthase, PLP-dependent; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. (407 aa) |
| | ALO43498.1 | Pfam:pfam00015 Methyl-accepting chemotaxis protein (MCP) signalling domain. (618 aa) |
| | ALO43499.1 | Hypothetical protein; Pfam:pfam13528 Glycosyl transferase family 1. (341 aa) |
| | rraA | 4-hydroxy-4-methyl-2-oxoglutarate aldolase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome. (169 aa) |
| | ALO43501.1 | Arginase/agmatinase/formiminoglutamase; Pfam:pfam00491 Arginase family; Belongs to the arginase family. (350 aa) |
| | cysQ-2 | 3''''-5''''-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (266 aa) |
| | ALO43555.1 | Hydrolase; Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. (220 aa) |
| | dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | ALO43618.1 | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (246 aa) |
| | ALO43619.1 | Pfam:pfam02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (401 aa) |
| | ALO43620.1 | Pfam:pfam04952 Succinylglutamate desuccinylase / Aspartoacylase family. (370 aa) |
| | argA | Amino-acid acetyltransferase; Pfam:pfam00696 Amino acid kinase family; Belongs to the acetyltransferase family. ArgA subfamily. (446 aa) |
| | ALO43957.1 | Aspartokinase; Pfam:pfam00696 Amino acid kinase family; Belongs to the aspartokinase family. (406 aa) |
| | ALO44049.1 | Racemase; Pfam:pfam01177 Asp/Glu/Hydantoin racemase. (236 aa) |
| | ALO44126.1 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (347 aa) |
| | ALO44141.1 | Flavodoxin; Pfam:pfam00258 Flavodoxin. (454 aa) |
| | ALO44227.1 | Pfam:pfam00733 Asparagine synthase. (556 aa) |
| | ALO40913.1 | dUMP phosphatase; Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. (228 aa) |
| | ALO44394.1 | Transporter; Pfam:pfam07662 Na+ dependent nucleoside transporter C-terminus; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (408 aa) |
| | ALO44395.1 | Uridine kinase; Pfam:pfam00485 Phosphoribulokinase / Uridine kinase family. (209 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (404 aa) |
| | deoD | Purine nucleoside phosphorylase DeoD-type; Pfam:pfam01048 Phosphorylase superfamily. (233 aa) |
| | tdk | Pfam:pfam00265 Thymidine kinase. (193 aa) |
| | ALO44587.1 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (286 aa) |
| | ALO44588.1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (255 aa) |
| | ALO44602.1 | Bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic; Pfam:pfam02872 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family. (521 aa) |
| | ALO44617.1 | Hypothetical protein. (217 aa) |
| | dapA-2 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (342 aa) |
| | argD-2 | Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa) |
| | ALO44651.1 | Decarboxylase family protein; Pfam:pfam11892 Domain of unknown function (DUF3412). (446 aa) |
| | hisI | Pfam:pfam01502 Phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. (203 aa) |
| | hisF | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Pfam:pfam00977 Histidine biosynthesis protein. (244 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa) |
| | hisB | Pfam:pfam00475 Imidazoleglycerol-phosphate dehydratase; In the N-terminal section; belongs to the histidinol- phosphatase family. (353 aa) |
| | ALO44659.1 | Histidinol phosphate aminotransferase; Pfam:pfam00155 Aminotransferase class I and II. (327 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (429 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (299 aa) |
| | ALO44662.1 | Hypothetical protein. (75 aa) |
| | asd-2 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (369 aa) |
| | ALO44695.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Pfam:pfam01474 Class-II DAHP synthetase family. (449 aa) |
| | ALO40954.1 | Asparagine synthetase; Pfam:pfam13537 Glutamine amidotransferase domain. (617 aa) |
| | ALO40990.1 | Bmp6; Pfam:pfam01947 Protein of unknown function (DUF98). (209 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (276 aa) |
| | ALO41116.1 | Hypothetical protein. (190 aa) |
| | gcvT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (360 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (963 aa) |
| | add | Pfam:pfam00962 Adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (332 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | PP2015_67 | FMN reductase; Pfam:pfam00175 Oxidoreductase NAD-binding domain. (237 aa) |
| | ALO41240.1 | 4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (174 aa) |
| | ubiA | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (291 aa) |
| | ALO41275.1 | Pfam:pfam00294 pfkB family carbohydrate kinase. (434 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1294 aa) |
