STRINGSTRING
ENSAPEP00000028701 ENSAPEP00000028701 ENSAPEP00000015272 ENSAPEP00000015272 ENSAPEP00000015753 ENSAPEP00000015753 ENSAPEP00000015808 ENSAPEP00000015808 ENSAPEP00000015906 ENSAPEP00000015906 ENSAPEP00000015971 ENSAPEP00000015971 ENSAPEP00000016081 ENSAPEP00000016081 LSM1 LSM1 ENSAPEP00000016439 ENSAPEP00000016439 DXO DXO ENSAPEP00000017864 ENSAPEP00000017864 ENSAPEP00000018765 ENSAPEP00000018765 ENSAPEP00000019615 ENSAPEP00000019615 ENSAPEP00000019747 ENSAPEP00000019747 ENSAPEP00000019877 ENSAPEP00000019877 ENSAPEP00000020104 ENSAPEP00000020104 ENSAPEP00000020195 ENSAPEP00000020195 ENSAPEP00000020823 ENSAPEP00000020823 ENSAPEP00000020942 ENSAPEP00000020942 ENSAPEP00000020977 ENSAPEP00000020977 ENSAPEP00000021007 ENSAPEP00000021007 ENSAPEP00000021024 ENSAPEP00000021024 ENSAPEP00000021216 ENSAPEP00000021216 ENSAPEP00000021318 ENSAPEP00000021318 ENSAPEP00000021659 ENSAPEP00000021659 ENSAPEP00000021700 ENSAPEP00000021700 ENSAPEP00000023845 ENSAPEP00000023845 ENSAPEP00000023081 ENSAPEP00000023081 ENSAPEP00000023048 ENSAPEP00000023048 ENSAPEP00000021785 ENSAPEP00000021785 ENSAPEP00000021716 ENSAPEP00000021716 ENSAPEP00000013489 ENSAPEP00000013489 ENSAPEP00000013033 ENSAPEP00000013033 ENSAPEP00000011998 ENSAPEP00000011998 SAMD4B SAMD4B ENSAPEP00000011141 ENSAPEP00000011141 ENSAPEP00000011025 ENSAPEP00000011025 ENSAPEP00000010917 ENSAPEP00000010917 ENSAPEP00000010798 ENSAPEP00000010798 ENSAPEP00000010671 ENSAPEP00000010671 ENSAPEP00000009957 ENSAPEP00000009957 ENSAPEP00000009572 ENSAPEP00000009572 ENSAPEP00000009471 ENSAPEP00000009471 ENSAPEP00000009442 ENSAPEP00000009442 ENSAPEP00000009283 ENSAPEP00000009283 ENSAPEP00000009248 ENSAPEP00000009248 ENSAPEP00000009239 ENSAPEP00000009239 UPF1 UPF1 ENSAPEP00000008687 ENSAPEP00000008687 LSM4 LSM4 ENSAPEP00000008558 ENSAPEP00000008558 ENSAPEP00000008410 ENSAPEP00000008410 ENSAPEP00000008124 ENSAPEP00000008124 ENSAPEP00000007724 ENSAPEP00000007724 ENSAPEP00000007713 ENSAPEP00000007713 ENSAPEP00000007490 ENSAPEP00000007490 ENSAPEP00000007455 ENSAPEP00000007455 ENSAPEP00000006888 ENSAPEP00000006888 ENSAPEP00000006815 ENSAPEP00000006815 ENSAPEP00000006270 ENSAPEP00000006270 ENSAPEP00000006193 ENSAPEP00000006193 EIF2C3 EIF2C3 CNOT9 CNOT9 ENSAPEP00000005527 ENSAPEP00000005527 ENSAPEP00000004881 ENSAPEP00000004881 ENSAPEP00000004387 ENSAPEP00000004387 ENSAPEP00000003918 ENSAPEP00000003918 PNPT1 PNPT1 ENSAPEP00000003032 ENSAPEP00000003032 ENSAPEP00000002928 ENSAPEP00000002928 NCBP1 NCBP1 ENSAPEP00000001573 ENSAPEP00000001573 ENSAPEP00000001305 ENSAPEP00000001305 ENSAPEP00000001018 ENSAPEP00000001018 ENSAPEP00000000941 ENSAPEP00000000941 ENSAPEP00000000215 ENSAPEP00000000215 ENSAPEP00000034732 ENSAPEP00000034732 ENSAPEP00000034416 ENSAPEP00000034416 CNOT2 CNOT2 ENSAPEP00000033764 ENSAPEP00000033764 ENSAPEP00000033543 ENSAPEP00000033543 ENSAPEP00000032945 ENSAPEP00000032945 ENSAPEP00000032364 ENSAPEP00000032364 ENSAPEP00000032292 ENSAPEP00000032292 ENSAPEP00000032171 ENSAPEP00000032171 PAN2 PAN2 ENSAPEP00000031939 ENSAPEP00000031939 dis3l2 dis3l2 ENSAPEP00000031589 ENSAPEP00000031589 ENSAPEP00000031572 ENSAPEP00000031572 ENSAPEP00000030659 ENSAPEP00000030659 ENSAPEP00000030573 ENSAPEP00000030573 ENSAPEP00000030111 ENSAPEP00000030111 ENSAPEP00000030067 ENSAPEP00000030067 ENSAPEP00000029039 ENSAPEP00000029039 ENSAPEP00000028733 ENSAPEP00000028733 ENSAPEP00000028712 ENSAPEP00000028712 ENSAPEP00000015059 ENSAPEP00000015059 EIF2C3-2 EIF2C3-2 ENSAPEP00000028412 ENSAPEP00000028412 PAN3 PAN3 ENSAPEP00000028243 ENSAPEP00000028243 TUT4 TUT4 ENSAPEP00000027140 ENSAPEP00000027140 ENSAPEP00000026933 ENSAPEP00000026933 UPF2 UPF2 ENSAPEP00000026872 ENSAPEP00000026872 ENSAPEP00000026331 ENSAPEP00000026331 ENSAPEP00000026294 ENSAPEP00000026294 ENSAPEP00000025993 ENSAPEP00000025993 AGO2 AGO2 ENSAPEP00000025411 ENSAPEP00000025411 ENSAPEP00000025078 ENSAPEP00000025078 ENSAPEP00000024832 ENSAPEP00000024832 ENSAPEP00000024233 ENSAPEP00000024233 ENSAPEP00000023862 ENSAPEP00000023862 ENSAPEP00000013631 ENSAPEP00000013631 ENSAPEP00000014362 ENSAPEP00000014362 ENSAPEP00000015053 ENSAPEP00000015053
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSAPEP00000028701U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (108 aa)
ENSAPEP00000015272Reactive intermediate imine deaminase A homolog. (135 aa)
ENSAPEP00000015753Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
ENSAPEP00000015808Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
ENSAPEP00000015906PAT1 homolog 2. (598 aa)
ENSAPEP00000015971CCR4-NOT transcription complex, subunit 2. (523 aa)
ENSAPEP00000016081Uncharacterized protein. (495 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
ENSAPEP00000016439CCR4-NOT transcription complex subunit 9. (310 aa)
DXODecapping exoribonuclease. (426 aa)
ENSAPEP00000017864Decapping mRNA 1A. (506 aa)
ENSAPEP00000018765Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (184 aa)
ENSAPEP00000019615U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (594 aa)
ENSAPEP00000019747Exosome component 2. (293 aa)
ENSAPEP00000019877Exosome component 5. (219 aa)
ENSAPEP00000020104Uncharacterized protein; Belongs to the MT-A70-like family. (406 aa)
ENSAPEP00000020195Exosome component 9. (427 aa)
ENSAPEP000000208235'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (973 aa)
ENSAPEP00000020942Uncharacterized protein. (331 aa)
ENSAPEP00000020977Uncharacterized protein. (155 aa)
ENSAPEP00000021007C2H2-type domain-containing protein. (160 aa)
ENSAPEP00000021024Decapping mRNA 2. (390 aa)
ENSAPEP00000021216Eukaryotic translation termination factor 1b. (443 aa)
ENSAPEP00000021318Decapping enzyme, scavenger. (327 aa)
ENSAPEP00000021659SMG9 nonsense mediated mRNA decay factor. (518 aa)
ENSAPEP00000021700Zgc:162730. (406 aa)
ENSAPEP00000023845CBP80/20-dependent translation initiation factor. (688 aa)
ENSAPEP00000023081Uncharacterized protein. (117 aa)
ENSAPEP00000023048Uncharacterized protein. (1113 aa)
ENSAPEP00000021785Nocturnin. (388 aa)
ENSAPEP00000021716Zgc:114130. (437 aa)
ENSAPEP00000013489SWT1 RNA endoribonuclease homolog. (966 aa)
ENSAPEP00000013033CCR4-NOT transcription complex, subunit 7. (286 aa)
ENSAPEP00000011998Ring finger and CCCH-type domains 1b. (1132 aa)
SAMD4BSterile alpha motif domain containing 4B. (671 aa)
ENSAPEP00000011141Neuroblastoma amplified sequence. (2234 aa)
ENSAPEP00000011025SMG7 nonsense mediated mRNA decay factor. (1196 aa)
ENSAPEP00000010917Enhancer of mRNA decapping 3. (474 aa)
ENSAPEP00000010798Ring finger and CCCH-type domains 2. (1153 aa)
ENSAPEP00000010671Reactive intermediate imine deaminase A homolog. (136 aa)
ENSAPEP00000009957Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa)
ENSAPEP00000009572Zinc finger protein 36, C3H type-like 2. (429 aa)
ENSAPEP00000009471SUV3-like helicase. (782 aa)
ENSAPEP00000009442Casc3 exon junction complex subunit. (755 aa)
ENSAPEP00000009283Methyltransferase like 3; Belongs to the MT-A70-like family. (592 aa)
ENSAPEP000000092485'-3' exoribonuclease 1. (1717 aa)
ENSAPEP00000009239CCR4-NOT transcription complex, subunit 3a. (899 aa)
UPF1UPF1 RNA helicase and ATPase. (1101 aa)
ENSAPEP00000008687CCR4-NOT transcription complex, subunit 8. (285 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (149 aa)
ENSAPEP00000008558Uncharacterized protein. (337 aa)
ENSAPEP00000008410Zinc finger CCCH-type containing 12A. (631 aa)
ENSAPEP00000008124TATA box binding protein. (281 aa)
ENSAPEP00000007724UPF3B regulator of nonsense mediated mRNA decay. (457 aa)
ENSAPEP00000007713TATA box binding protein. (300 aa)
ENSAPEP00000007490Uncharacterized protein. (111 aa)
ENSAPEP00000007455CCR4-NOT transcription complex, subunit 10. (746 aa)
ENSAPEP00000006888Proline-rich nuclear receptor coactivator 2. (156 aa)
ENSAPEP00000006815Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (235 aa)
ENSAPEP00000006270Decapping mRNA 1B. (659 aa)
ENSAPEP00000006193Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
EIF2C3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
ENSAPEP00000005527Exosome component 4. (279 aa)
ENSAPEP00000004881UPF3A regulator of nonsense mediated mRNA decay. (463 aa)
ENSAPEP00000004387Mitochondrial poly(A) polymerase. (593 aa)
ENSAPEP00000003918CCR4-NOT transcription complex, subunit 3b. (849 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (729 aa)
ENSAPEP00000003032Uncharacterized protein. (2902 aa)
ENSAPEP00000002928SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3577 aa)
NCBP1Nuclear cap binding protein subunit 1. (795 aa)
ENSAPEP00000001573SKI2 homolog, superkiller viralicidic activity 2-like. (1243 aa)
ENSAPEP00000001305Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
ENSAPEP00000001018Phosphodiesterase 12. (586 aa)
ENSAPEP00000000941LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (177 aa)
ENSAPEP00000000215Sterile alpha motif domain containing 4A. (471 aa)
ENSAPEP00000034732MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (728 aa)
ENSAPEP00000034416LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (125 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (958 aa)
ENSAPEP00000033764LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
ENSAPEP00000033543Enhancer of mRNA decapping 4. (1390 aa)
ENSAPEP00000032945Mago homolog, exon junction complex subunit. (161 aa)
ENSAPEP00000032364SMG5 nonsense mediated mRNA decay factor. (1123 aa)
ENSAPEP00000032292Exosome component 6. (274 aa)
ENSAPEP00000032171RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (207 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1210 aa)
ENSAPEP00000031939PYM homolog 1, exon junction complex associated factor. (210 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1060 aa)
ENSAPEP00000031589CCR4-NOT transcription complex, subunit 1. (2332 aa)
ENSAPEP00000031572Sb:cb81. (376 aa)
ENSAPEP00000030659Si:dkey-206d17.12. (259 aa)
ENSAPEP00000030573SMG8 nonsense mediated mRNA decay factor. (924 aa)
ENSAPEP00000030111PAT1 homolog 1, processing body mRNA decay factor. (844 aa)
ENSAPEP00000030067Nudix (nucleoside diphosphate linked moiety X)-type motif 12. (452 aa)
ENSAPEP00000029039Non-specific serine/threonine protein kinase. (3038 aa)
ENSAPEP00000028733Exosome component 8. (268 aa)
ENSAPEP00000028712Small RNA binding exonuclease protection factor La. (397 aa)
ENSAPEP00000015059Uncharacterized protein. (96 aa)
EIF2C3-2Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
ENSAPEP00000028412Zinc finger, CCHC domain containing 7. (655 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (793 aa)
ENSAPEP00000028243CCR4-NOT transcription complex, subunit 6-like. (533 aa)
TUT4Terminal uridylyl transferase 4. (1536 aa)
ENSAPEP00000027140CCR4-NOT transcription complex, subunit 11. (393 aa)
ENSAPEP00000026933Nanos homolog 2; Belongs to the nanos family. (159 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1276 aa)
ENSAPEP00000026872SMG6 nonsense mediated mRNA decay factor. (1647 aa)
ENSAPEP00000026331Polymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
ENSAPEP00000026294Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa)
ENSAPEP00000025993Exosome component 3. (275 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (875 aa)
ENSAPEP00000025411Nocturnin. (449 aa)
ENSAPEP00000025078Exosome component 10. (901 aa)
ENSAPEP00000024832YTH N(6)-methyladenosine RNA binding protein 2. (639 aa)
ENSAPEP00000024233Tetratricopeptide repeat domain 37. (1484 aa)
ENSAPEP00000023862CCR4-NOT transcription complex, subunit 6a. (570 aa)
ENSAPEP00000013631Exosome component 7. (291 aa)
ENSAPEP00000014362Zinc finger protein 36, C3H type-like 1a. (372 aa)
ENSAPEP00000015053Poly(A)-specific ribonuclease (deadenylation nuclease). (521 aa)
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
Server load: low (26%) [HD]