(24 nodes) Receptor signaling pathway via JAK-STAT network (Amphiprion percula)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000016127	Interleukin; Belongs to the IL-15/IL-21 family. (170 aa)
	ENSAPEP00000034362	Suppressor of cytokine signaling 2. (197 aa)
	ENSAPEP00000032811	Suppressor of cytokine signaling 3. (228 aa)
	ENSAPEP00000027803	Polycystic kidney disease 1b. (2913 aa)
	ENSAPEP00000026167	Signal transducer and activator of transcription. (711 aa)
	ENSAPEP00000026140	Signal transducer and activator of transcription. (786 aa)
	ENSAPEP00000025897	Signal transducer and activator of transcription. (790 aa)
	ENSAPEP00000024426	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (434 aa)
	ENSAPEP00000022369	Signal transducer and activator of transcription. (815 aa)
	ENSAPEP00000021803	Signal transducer and activator of transcription. (786 aa)
	ENSAPEP00000018939	Suppressor of cytokine signaling 1a. (199 aa)
	ENSAPEP00000018555	Tyrosine-protein kinase. (1113 aa)
	ENSAPEP00000018198	Uncharacterized protein. (161 aa)
	ENSAPEP00000018133	Polycystic kidney disease 1a. (4595 aa)
	ENSAPEP00000015177	Tyrosine-protein kinase. (1171 aa)
	ENSAPEP00000015139	Tyrosine-protein kinase. (1179 aa)
	ENSAPEP00000014565	CTR9 homolog, Paf1/RNA polymerase II complex component. (1162 aa)
	ENSAPEP00000010977	Tyrosine-protein kinase. (1134 aa)
	ENSAPEP00000007066	Signal transducer and activator of transcription. (764 aa)
	ENSAPEP00000006096	Tyrosine-protein kinase. (1114 aa)
	ENSAPEP00000005428	Suppressor of cytokine signaling 3a. (206 aa)
	ENSAPEP00000005328	Signal transducer and activator of transcription. (778 aa)
	ENSAPEP00000005286	Signal transducer and activator of transcription. (734 aa)
	ENSAPEP00000001529	Uncharacterized protein. (702 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ENSAPEP00000001529	ENSAPEP00000005286	Uncharacterized protein.	Signal transducer and activator of transcription.	0.539
ENSAPEP00000001529	ENSAPEP00000005328	Uncharacterized protein.	Signal transducer and activator of transcription.	0.511
ENSAPEP00000001529	ENSAPEP00000006096	Uncharacterized protein.	Tyrosine-protein kinase.	0.852
ENSAPEP00000001529	ENSAPEP00000007066	Uncharacterized protein.	Signal transducer and activator of transcription.	0.560
ENSAPEP00000001529	ENSAPEP00000010977	Uncharacterized protein.	Tyrosine-protein kinase.	0.852
ENSAPEP00000001529	ENSAPEP00000015139	Uncharacterized protein.	Tyrosine-protein kinase.	0.852
ENSAPEP00000001529	ENSAPEP00000015177	Uncharacterized protein.	Tyrosine-protein kinase.	0.852
ENSAPEP00000001529	ENSAPEP00000016127	Uncharacterized protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.885
ENSAPEP00000001529	ENSAPEP00000018555	Uncharacterized protein.	Tyrosine-protein kinase.	0.852
ENSAPEP00000001529	ENSAPEP00000021803	Uncharacterized protein.	Signal transducer and activator of transcription.	0.653
ENSAPEP00000001529	ENSAPEP00000022369	Uncharacterized protein.	Signal transducer and activator of transcription.	0.539
ENSAPEP00000001529	ENSAPEP00000025897	Uncharacterized protein.	Signal transducer and activator of transcription.	0.550
ENSAPEP00000001529	ENSAPEP00000026140	Uncharacterized protein.	Signal transducer and activator of transcription.	0.653
ENSAPEP00000001529	ENSAPEP00000026167	Uncharacterized protein.	Signal transducer and activator of transcription.	0.653
ENSAPEP00000005286	ENSAPEP00000001529	Signal transducer and activator of transcription.	Uncharacterized protein.	0.539
ENSAPEP00000005286	ENSAPEP00000005328	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.784
ENSAPEP00000005286	ENSAPEP00000005428	Signal transducer and activator of transcription.	Suppressor of cytokine signaling 3a.	0.766
ENSAPEP00000005286	ENSAPEP00000006096	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.944
ENSAPEP00000005286	ENSAPEP00000010977	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.942
ENSAPEP00000005286	ENSAPEP00000015139	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.946