(128 nodes) Ubiquitin-like protein peptidase activity network (Amphiprion percula)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000008178	Ubiquitin carboxyl-terminal hydrolase. (827 aa)
	ENSAPEP00000007938	USP domain-containing protein; Belongs to the peptidase C19 family. (353 aa)
	ENSAPEP00000007815	Valosin containing protein (p97)/p47 complex interacting protein 1. (1184 aa)
	ENSAPEP00000007719	Ubiquitin specific peptidase 21; Belongs to the peptidase C19 family. (230 aa)
	ENSAPEP00000007661	MPN domain containing. (454 aa)
	ENSAPEP00000007593	ULP_PROTEASE domain-containing protein. (1014 aa)
	ENSAPEP00000007111	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (406 aa)
	ENSAPEP00000006786	Proteasome 26S subunit, non-ATPase 7. (328 aa)
	ENSAPEP00000001584	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (975 aa)
	ENSAPEP00000006309	Ubiquitin carboxyl-terminal hydrolase. (231 aa)
	ENSAPEP00000005994	Ubiquitin carboxyl-terminal hydrolase. (959 aa)
	ENSAPEP00000005299	Si:dkey-30h22.11. (693 aa)
	COPS6	COP9 signalosome subunit 6. (316 aa)
	ENSAPEP00000005167	Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1134 aa)
	ENSAPEP00000005068	Tumor necrosis factor, alpha-induced protein 3. (825 aa)
	ENSAPEP00000005016	Si:dkey-21c19.3. (690 aa)
	ENSAPEP00000005014	ULP_PROTEASE domain-containing protein. (535 aa)
	ENSAPEP00000004884	Ubiquitin specific peptidase 2a; Belongs to the peptidase C19 family. (336 aa)
	ENSAPEP00000004369	Ubiquitin carboxyl-terminal hydrolase. (522 aa)
	ENSAPEP00000004240	Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2551 aa)
	ENSAPEP00000003649	SUMO peptidase family member, NEDD8 specific. (221 aa)
	ENSAPEP00000003421	Ubiquitin specific peptidase 11; Belongs to the peptidase C19 family. (1013 aa)
	ENSAPEP00000002916	Uncharacterized protein. (354 aa)
	DESI1	Desumoylating isopeptidase 1. (168 aa)
	ENSAPEP00000032979	Ubiquitin carboxyl-terminal hydrolase. (220 aa)
	ENSAPEP00000032241	Ubiquitin specific peptidase 54b. (292 aa)
	ENSAPEP00000032168	OTU deubiquitinase 5a. (551 aa)
	ENSAPEP00000032141	OTU deubiquitinase 7B. (923 aa)
	USP53	Ubiquitin specific peptidase 53. (1045 aa)
	ENSAPEP00000016824	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1289 aa)
	ENSAPEP00000016709	Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1171 aa)
	ENSAPEP00000016672	Ubiquitin carboxyl-terminal hydrolase. (403 aa)
	ENSAPEP00000016648	Centrosomal protein 112. (912 aa)
	ENSAPEP00000016376	Ubiquitin carboxyl-terminal hydrolase. (880 aa)
	ENSAPEP00000016261	MINDY lysine 48 deubiquitinase 1. (593 aa)
	ENSAPEP00000016219	Ubiquitin carboxyl-terminal hydrolase. (829 aa)
	ENSAPEP00000016158	Ubiquitin carboxyl-terminal hydrolase. (815 aa)
	USP16	Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (846 aa)
	ENSAPEP00000015790	Ubiquitin specific peptidase 38; Belongs to the peptidase C19 family. (1036 aa)
	ENSAPEP00000015306	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1364 aa)
	ENSAPEP00000014341	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (956 aa)
	ENSAPEP00000013618	SUMO specific peptidase 5. (257 aa)
	ENSAPEP00000027065	MINDY family member 4B. (330 aa)
	EIF3F	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (270 aa)
	ENSAPEP00000026552	UFM1-specific peptidase 1 (non-functional). (244 aa)
	ENSAPEP00000026334	Uncharacterized protein. (290 aa)
	ENSAPEP00000026322	STAM binding protein b. (435 aa)
	ENSAPEP00000001405	Ubiquitin carboxyl-terminal hydrolase. (491 aa)
	ENSAPEP00000001174	Ubiquitin specific peptidase 43a; Belongs to the peptidase C19 family. (1164 aa)
	USP42	Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family. (977 aa)
	ENSAPEP00000000737	USP domain-containing protein; Belongs to the peptidase C19 family. (219 aa)
	SENP6	SUMO specific peptidase 6. (1081 aa)
	ENSAPEP00000031849	Ubiquitin carboxyl-terminal hydrolase. (941 aa)
	ENSAPEP00000031197	Ubiquitin carboxyl-terminal hydrolase. (744 aa)
	ENSAPEP00000030659	Si:dkey-206d17.12. (259 aa)
	ENSAPEP00000029307	COP9 signalosome subunit 5. (334 aa)
	ENSAPEP00000029182	Desumoylating isopeptidase 1b. (164 aa)
	ENSAPEP00000029139	Ubiquitin carboxyl-terminal hydrolase. (809 aa)
	ENSAPEP00000029105	Josephin domain containing 1. (257 aa)
	ZRANB1	Zinc finger RANBP2-type containing 1. (361 aa)
	ENSAPEP00000028902	Uncharacterized protein. (294 aa)
	ENSAPEP00000028705	BRCA1/BRCA2-containing complex, subunit 3. (265 aa)
	ENSAPEP00000028257	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family. (754 aa)
	ENSAPEP00000028044	Ubiquitin specific peptidase 12a; Belongs to the peptidase C19 family. (372 aa)
	ENSAPEP00000026070	Ubiquitin carboxyl-terminal hydrolase. (478 aa)
	ENSAPEP00000025915	Ubiquitin specific peptidase 4 (proto-oncogene); Belongs to the peptidase C19 family. (1034 aa)
	ENSAPEP00000025854	Ubiquitin specific peptidase 19. (1307 aa)
	EIF3H	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (341 aa)
	ENSAPEP00000023621	Uncharacterized protein. (929 aa)
	ENSAPEP00000023342	Ubiquitin specific peptidase 53b. (321 aa)
	ENSAPEP00000023277	Ubiquitin thioesterase. (280 aa)
	ENSAPEP00000022954	Ubiquitin carboxyl-terminal hydrolase. (329 aa)
	ENSAPEP00000022911	OTU deubiquitinase 1. (402 aa)
	ENSAPEP00000022852	Ufm1-specific peptidase 2. (469 aa)
	ENSAPEP00000021638	Ubiquitin carboxyl-terminal hydrolase. (405 aa)
	ENSAPEP00000021037	USP domain-containing protein; Belongs to the peptidase C19 family. (321 aa)
	ENSAPEP00000021002	Uncharacterized protein. (367 aa)
	ENSAPEP00000021000	Ubiquitin carboxyl-terminal hydrolase. (743 aa)
	ENSAPEP00000020911	Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1312 aa)
	ENSAPEP00000020721	Ubiquitin carboxyl-terminal hydrolase. (677 aa)
	ENSAPEP00000020599	Ubiquitin specific peptidase 12b; Belongs to the peptidase C19 family. (336 aa)
	USP15	Ubiquitin specific peptidase 15; Belongs to the peptidase C19 family. (1009 aa)
	ENSAPEP00000020081	SUMO specific peptidase 2. (526 aa)
	ENSAPEP00000019692	Uncharacterized protein. (1274 aa)
	ENSAPEP00000019616	Ubiquitin carboxyl-terminal hydrolase. (634 aa)
	ENSAPEP00000018705	OTU domain containing 6B. (297 aa)
	ENSAPEP00000018666	Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (2597 aa)
	ENSAPEP00000018665	Si:ch73-302o18.2. (338 aa)
	ENSAPEP00000018484	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
	ENSAPEP00000018140	Proline-rich transmembrane protein 4. (850 aa)
	ENSAPEP00000018130	Myb-like, SWIRM and MPN domains 1. (835 aa)
	ENSAPEP00000018076	Uncharacterized protein. (1060 aa)
	ENSAPEP00000017904	OTU deubiquitinase with linear linkage specificity a. (731 aa)
	ENSAPEP00000017618	Cytochrome c oxidase assembly factor COX20. (115 aa)
	ENSAPEP00000034889	Ubiquitin carboxyl-terminal hydrolase. (904 aa)
	USP50	Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (306 aa)
	ENSAPEP00000034453	Ubiquitin specific peptidase 39. (499 aa)
	ENSAPEP00000034279	Cylindromatosis (turban tumor syndrome), b. (707 aa)
	ENSAPEP00000034168	Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (1050 aa)
	ENSAPEP00000033570	YOD1 deubiquitinase. (324 aa)
	ENSAPEP00000033488	Ataxin 3. (354 aa)
	OTUB2	OTU deubiquitinase, ubiquitin aldehyde binding 2. (229 aa)
	ENSAPEP00000033459	DUF862 domain-containing protein. (211 aa)
	ENSAPEP00000033328	Proteasome 26S subunit, non-ATPase 14. (324 aa)
	ENSAPEP00000033081	Ubiquitin carboxyl-terminal hydrolase. (503 aa)
	OTUD7A	OTU deubiquitinase 7A. (975 aa)
	ENSAPEP00000027191	Ubiquitin specific peptidase like 1. (1170 aa)
	USP22	Ubiquitin carboxyl-terminal hydrolase. (506 aa)
	ENSAPEP00000027860	Ubiquitin specific peptidase 18; Belongs to the peptidase C19 family. (371 aa)
	ENSAPEP00000027937	Ubiquitin carboxyl-terminal hydrolase. (623 aa)
	ENSAPEP00000012637	OTU deubiquitinase 3. (358 aa)
	ENSAPEP00000012660	Uncharacterized protein. (148 aa)
	ENSAPEP00000013119	DUF862 domain-containing protein. (197 aa)
	ENSAPEP00000013284	STAM binding protein-like 1. (429 aa)
	ENSAPEP00000013498	USP domain-containing protein. (344 aa)
	ENSAPEP00000013530	SUMO specific peptidase 3b. (552 aa)
	ENSAPEP00000031914	MINDY lysine 48 deubiquitinase 3. (504 aa)
	ENSAPEP00000017336	MINDY lysine 48 deubiquitinase 2. (662 aa)
	ENSAPEP00000016990	Ubiquitin carboxyl-terminal hydrolase. (949 aa)
	ENSAPEP00000011875	Josephin domain containing 2. (182 aa)
	ENSAPEP00000011282	annotation not available (316 aa)
	ENSAPEP00000010133	Si:dkey-31f5.11. (1085 aa)
	ENSAPEP00000009978	Zinc finger, RAN-binding domain containing 1b. (761 aa)
	ENSAPEP00000009730	USP domain-containing protein; Belongs to the peptidase C19 family. (518 aa)
	ENSAPEP00000009601	Ubiquitin carboxyl-terminal hydrolase. (938 aa)
	USP34	Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (2939 aa)
	ENSAPEP00000008410	Zinc finger CCCH-type containing 12A. (631 aa)
	ENSAPEP00000008189	Ubiquitin specific peptidase 32; Belongs to the peptidase C19 family. (1585 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS6	EIF3H	ENSAPEP00000005197	ENSAPEP00000023675	COP9 signalosome subunit 6.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.935
COPS6	ENSAPEP00000001405	ENSAPEP00000005197	ENSAPEP00000001405	COP9 signalosome subunit 6.	Ubiquitin carboxyl-terminal hydrolase.	0.839
COPS6	ENSAPEP00000003649	ENSAPEP00000005197	ENSAPEP00000003649	COP9 signalosome subunit 6.	SUMO peptidase family member, NEDD8 specific.	0.618
COPS6	ENSAPEP00000006309	ENSAPEP00000005197	ENSAPEP00000006309	COP9 signalosome subunit 6.	Ubiquitin carboxyl-terminal hydrolase.	0.465
COPS6	ENSAPEP00000006786	ENSAPEP00000005197	ENSAPEP00000006786	COP9 signalosome subunit 6.	Proteasome 26S subunit, non-ATPase 7.	0.423
COPS6	ENSAPEP00000007111	ENSAPEP00000005197	ENSAPEP00000007111	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).	0.994
COPS6	ENSAPEP00000010133	ENSAPEP00000005197	ENSAPEP00000010133	COP9 signalosome subunit 6.	Si:dkey-31f5.11.	0.465
COPS6	ENSAPEP00000016648	ENSAPEP00000005197	ENSAPEP00000016648	COP9 signalosome subunit 6.	Centrosomal protein 112.	0.465
COPS6	ENSAPEP00000018076	ENSAPEP00000005197	ENSAPEP00000018076	COP9 signalosome subunit 6.	Uncharacterized protein.	0.465
COPS6	ENSAPEP00000018130	ENSAPEP00000005197	ENSAPEP00000018130	COP9 signalosome subunit 6.	Myb-like, SWIRM and MPN domains 1.	0.483
COPS6	ENSAPEP00000018140	ENSAPEP00000005197	ENSAPEP00000018140	COP9 signalosome subunit 6.	Proline-rich transmembrane protein 4.	0.465
COPS6	ENSAPEP00000021000	ENSAPEP00000005197	ENSAPEP00000021000	COP9 signalosome subunit 6.	Ubiquitin carboxyl-terminal hydrolase.	0.835
COPS6	ENSAPEP00000022954	ENSAPEP00000005197	ENSAPEP00000022954	COP9 signalosome subunit 6.	Ubiquitin carboxyl-terminal hydrolase.	0.835
COPS6	ENSAPEP00000029307	ENSAPEP00000005197	ENSAPEP00000029307	COP9 signalosome subunit 6.	COP9 signalosome subunit 5.	0.995
COPS6	ENSAPEP00000032979	ENSAPEP00000005197	ENSAPEP00000032979	COP9 signalosome subunit 6.	Ubiquitin carboxyl-terminal hydrolase.	0.465
COPS6	ENSAPEP00000033328	ENSAPEP00000005197	ENSAPEP00000033328	COP9 signalosome subunit 6.	Proteasome 26S subunit, non-ATPase 14.	0.485
DESI1	ENSAPEP00000027191	ENSAPEP00000002593	ENSAPEP00000027191	Desumoylating isopeptidase 1.	Ubiquitin specific peptidase like 1.	0.461
EIF3F	EIF3H	ENSAPEP00000026902	ENSAPEP00000023675	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
EIF3F	ENSAPEP00000001405	ENSAPEP00000026902	ENSAPEP00000001405	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Ubiquitin carboxyl-terminal hydrolase.	0.838
EIF3F	ENSAPEP00000003649	ENSAPEP00000026902	ENSAPEP00000003649	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	SUMO peptidase family member, NEDD8 specific.	0.611