(49 nodes) Positive regulation of innate immune response network (Amphiprion percula)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000012117	Transmembrane protein 173. (409 aa)
	ENSAPEP00000034845	TANK-binding kinase 1. (716 aa)
	ENSAPEP00000033491	CARD domain-containing protein. (531 aa)
	ENSAPEP00000032452	Uncharacterized protein. (384 aa)
	ENSAPEP00000031688	Lysosomal associated membrane protein 1a. (415 aa)
	ENSAPEP00000031514	CD226 molecule. (317 aa)
	ENSAPEP00000031356	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (225 aa)
	ENSAPEP00000030203	Polyglutamine binding protein 1. (233 aa)
	ENSAPEP00000029683	Transcription elongation factor SPT5. (1014 aa)
	ENSAPEP00000029447	Zinc finger, NFX1-type containing 1. (1982 aa)
	ENSAPEP00000029150	Interferon-induced protein 35. (374 aa)
	ENSAPEP00000029147	X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa)
	ENSAPEP00000028490	Si:dkey-211g8.6. (306 aa)
	ENSAPEP00000027184	Akirin 2. (202 aa)
	ENSAPEP00000027131	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
	ENSAPEP00000024953	Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (578 aa)
	ENSAPEP00000024426	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (434 aa)
	ENSAPEP00000024365	Uncharacterized protein. (345 aa)
	ENSAPEP00000024288	RNA binding motif protein 4.3. (340 aa)
	ENSAPEP00000024077	Uncharacterized protein. (197 aa)
	ENSAPEP00000023273	Splicing factor proline/glutamine-rich. (698 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (291 aa)
	ENSAPEP00000022132	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (723 aa)
	ENSAPEP00000021868	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
	ENSAPEP00000021390	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
	ENSAPEP00000021305	EGF-like domain-containing protein. (155 aa)
	ENSAPEP00000021219	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1827 aa)
	ENSAPEP00000019670	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (284 aa)
	ENSAPEP00000019626	Uncharacterized protein. (107 aa)
	ENSAPEP00000019255	Polymerase (RNA) III (DNA directed) polypeptide D. (386 aa)
	ENSAPEP00000017063	LSM14A mRNA processing body assembly factor a. (439 aa)
	IL12B-2	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (355 aa)
	ENSAPEP00000015979	Non-POU domain containing, octamer-binding. (407 aa)
	ENSAPEP00000015499	Ring finger protein 185. (193 aa)
	ENSAPEP00000015372	LSM14A mRNA processing body assembly factor b. (446 aa)
	ENSAPEP00000013959	SH2 domain containing 1A duplicate b. (156 aa)
	ENSAPEP00000013904	Interferon regulatory factor 3. (464 aa)
	ENSAPEP00000012409	Akirin 2. (179 aa)
	ENSAPEP00000010532	Cell adhesion molecule 1b. (420 aa)
	ENSAPEP00000009947	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (721 aa)
	ENSAPEP00000009613	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1059 aa)
	CXorf21	Uncharacterized protein. (357 aa)
	ENSAPEP00000007718	SH2 domain-containing protein. (154 aa)
	ENSAPEP00000006024	G_PROTEIN_RECEP_F1_2 domain-containing protein. (336 aa)
	ENSAPEP00000005747	Tripartite motif containing 62, tandem duplicate 1. (475 aa)
	ENSAPEP00000005624	Uncharacterized protein. (191 aa)
	ENSAPEP00000005289	Matrin 3-like 1.1. (1122 aa)
	ENSAPEP00000003554	Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (510 aa)
	ENSAPEP00000001067	Cell adhesion molecule 1a. (424 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPEP00000001067	ENSAPEP00000010532	ENSAPEP00000001067	ENSAPEP00000010532	Cell adhesion molecule 1a.	Cell adhesion molecule 1b.	0.826
ENSAPEP00000001067	ENSAPEP00000019626	ENSAPEP00000001067	ENSAPEP00000019626	Cell adhesion molecule 1a.	Uncharacterized protein.	0.428
ENSAPEP00000005289	ENSAPEP00000009947	ENSAPEP00000005289	ENSAPEP00000009947	Matrin 3-like 1.1.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.418
ENSAPEP00000005289	ENSAPEP00000015979	ENSAPEP00000005289	ENSAPEP00000015979	Matrin 3-like 1.1.	Non-POU domain containing, octamer-binding.	0.633
ENSAPEP00000005289	ENSAPEP00000022132	ENSAPEP00000005289	ENSAPEP00000022132	Matrin 3-like 1.1.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.410
ENSAPEP00000005289	ENSAPEP00000023273	ENSAPEP00000005289	ENSAPEP00000023273	Matrin 3-like 1.1.	Splicing factor proline/glutamine-rich.	0.507
ENSAPEP00000005289	ENSAPEP00000024288	ENSAPEP00000005289	ENSAPEP00000024288	Matrin 3-like 1.1.	RNA binding motif protein 4.3.	0.492
ENSAPEP00000005289	ENSAPEP00000024365	ENSAPEP00000005289	ENSAPEP00000024365	Matrin 3-like 1.1.	Uncharacterized protein.	0.492
ENSAPEP00000005289	ENSAPEP00000034845	ENSAPEP00000005289	ENSAPEP00000034845	Matrin 3-like 1.1.	TANK-binding kinase 1.	0.418
ENSAPEP00000005624	ENSAPEP00000009947	ENSAPEP00000005624	ENSAPEP00000009947	Uncharacterized protein.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.664
ENSAPEP00000005624	ENSAPEP00000012117	ENSAPEP00000005624	ENSAPEP00000012117	Uncharacterized protein.	Transmembrane protein 173.	0.500
ENSAPEP00000005624	ENSAPEP00000013904	ENSAPEP00000005624	ENSAPEP00000013904	Uncharacterized protein.	Interferon regulatory factor 3.	0.533
ENSAPEP00000005624	ENSAPEP00000019626	ENSAPEP00000005624	ENSAPEP00000019626	Uncharacterized protein.	Uncharacterized protein.	0.665
ENSAPEP00000005624	ENSAPEP00000019670	ENSAPEP00000005624	ENSAPEP00000019670	Uncharacterized protein.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.686
ENSAPEP00000005624	ENSAPEP00000024077	ENSAPEP00000005624	ENSAPEP00000024077	Uncharacterized protein.	Uncharacterized protein.	0.525
ENSAPEP00000005624	ENSAPEP00000031356	ENSAPEP00000005624	ENSAPEP00000031356	Uncharacterized protein.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.865
ENSAPEP00000005624	ENSAPEP00000033491	ENSAPEP00000005624	ENSAPEP00000033491	Uncharacterized protein.	CARD domain-containing protein.	0.525
ENSAPEP00000005624	ENSAPEP00000034845	ENSAPEP00000005624	ENSAPEP00000034845	Uncharacterized protein.	TANK-binding kinase 1.	0.664
ENSAPEP00000005747	ENSAPEP00000012117	ENSAPEP00000005747	ENSAPEP00000012117	Tripartite motif containing 62, tandem duplicate 1.	Transmembrane protein 173.	0.455
ENSAPEP00000005747	ENSAPEP00000013904	ENSAPEP00000005747	ENSAPEP00000013904	Tripartite motif containing 62, tandem duplicate 1.	Interferon regulatory factor 3.	0.657