(50 nodes) Positive regulation of endocytosis network (Amphiprion percula)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000013463	Tumor susceptibility 101a. (390 aa)
	ENSAPEP00000013216	Abelson helper integration site 1. (872 aa)
	ENSAPEP00000012311	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (550 aa)
	ENSAPEP00000011061	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (664 aa)
	SCYL2	SCY1 like pseudokinase 2. (925 aa)
	ENSAPEP00000010017	Gremlin 1a, DAN family BMP antagonist. (179 aa)
	ENSAPEP00000009988	Uncharacterized protein. (91 aa)
	ENSAPEP00000009708	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (237 aa)
	ENSAPEP00000009387	Clusterin; Belongs to the clusterin family. (504 aa)
	ENSAPEP00000008058	Cell division cycle 42, like. (203 aa)
	ENSAPEP00000007849	PDZ domain-containing protein. (137 aa)
	ENSAPEP00000007819	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1133 aa)
	ENSAPEP00000007560	Calcyon neuron-specific vesicular protein. (178 aa)
	ENSAPEP00000004296	Low density lipoprotein receptor adaptor protein 1a. (310 aa)
	ENSAPEP00000003909	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (642 aa)
	ENSAPEP00000002373	Uncharacterized protein. (191 aa)
	ENSAPEP00000002067	DAB adaptor protein 2. (582 aa)
	GREM1	Gremlin; Belongs to the DAN family. (172 aa)
	ENSAPEP00000001146	Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase. (515 aa)
	ENSAPEP00000000293	Uncharacterized protein. (56 aa)
	ENSAPEP00000000292	Uncharacterized protein. (63 aa)
	ENSAPEP00000015044	Protein tyrosine phosphatase non-receptor type 5. (367 aa)
	ENSAPEP00000013406	Zgc:123278. (192 aa)
	ENSAPEP00000034178	Clusterin; Belongs to the clusterin family. (462 aa)
	ENSAPEP00000033322	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	ENSAPEP00000032695	Eukaryotic elongation factor 2 kinase. (748 aa)
	ENSAPEP00000032203	Tetraspanin. (240 aa)
	ENSAPEP00000031567	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (598 aa)
	ENSAPEP00000031131	Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (303 aa)
	ENSAPEP00000030371	annotation not available (260 aa)
	ENSAPEP00000029997	Battenin. (435 aa)
	ENSAPEP00000029233	Apolipoprotein Ea. (260 aa)
	ENSAPEP00000028737	PDZ domain-containing protein. (155 aa)
	ENSAPEP00000028673	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1146 aa)
	CDC42	Cell division cycle 42. (221 aa)
	ENSAPEP00000027350	Anoctamin. (948 aa)
	ENSAPEP00000026613	TBC1 domain family, member 5. (920 aa)
	ENSAPEP00000026312	Low density lipoprotein receptor adaptor protein 1b. (312 aa)
	ENSAPEP00000023725	Vitronectin b. (445 aa)
	ENSAPEP00000021742	Cell division cycle 42. (191 aa)
	ENSAPEP00000021487	Fragile X mental retardation 1. (605 aa)
	CLUL1	Clusterin; Belongs to the clusterin family. (462 aa)
	ENSAPEP00000020502	Leucine-rich repeat kinase 2. (2406 aa)
	ENSAPEP00000020431	Vitronectin a. (561 aa)
	ENSAPEP00000019965	Ankyrin repeat and FYVE domain containing 1. (1166 aa)
	ENSAPEP00000018720	Proprotein convertase subtilisin/kexin type 9. (658 aa)
	ENSAPEP00000017705	Protein interacting with prkca 1. (452 aa)
	ENSAPEP00000017218	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa)
	ENSAPEP00000016135	Uncharacterized protein. (393 aa)
	ENSAPEP00000015316	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (391 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSAPEP00000002373	ENSAPEP00000028432	ENSAPEP00000002373	Cell division cycle 42.	Uncharacterized protein.	0.770
CDC42	ENSAPEP00000003909	ENSAPEP00000028432	ENSAPEP00000003909	Cell division cycle 42.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.417
CDC42	ENSAPEP00000007819	ENSAPEP00000028432	ENSAPEP00000007819	Cell division cycle 42.	Membrane associated guanylate kinase, WW and PDZ domain containing 2b.	0.589
CDC42	ENSAPEP00000007849	ENSAPEP00000028432	ENSAPEP00000007849	Cell division cycle 42.	PDZ domain-containing protein.	0.589
CDC42	ENSAPEP00000008058	ENSAPEP00000028432	ENSAPEP00000008058	Cell division cycle 42.	Cell division cycle 42, like.	0.771
CDC42	ENSAPEP00000011061	ENSAPEP00000028432	ENSAPEP00000011061	Cell division cycle 42.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.417
CDC42	ENSAPEP00000019965	ENSAPEP00000028432	ENSAPEP00000019965	Cell division cycle 42.	Ankyrin repeat and FYVE domain containing 1.	0.657
CDC42	ENSAPEP00000028673	ENSAPEP00000028432	ENSAPEP00000028673	Cell division cycle 42.	Membrane associated guanylate kinase, WW and PDZ domain containing 2a.	0.589
CDC42	ENSAPEP00000028737	ENSAPEP00000028432	ENSAPEP00000028737	Cell division cycle 42.	PDZ domain-containing protein.	0.589
CLUL1	ENSAPEP00000002067	ENSAPEP00000020965	ENSAPEP00000002067	Clusterin; Belongs to the clusterin family.	DAB adaptor protein 2.	0.458
ENSAPEP00000000292	ENSAPEP00000029997	ENSAPEP00000000292	ENSAPEP00000029997	Uncharacterized protein.	Battenin.	0.443
ENSAPEP00000000293	ENSAPEP00000029997	ENSAPEP00000000293	ENSAPEP00000029997	Uncharacterized protein.	Battenin.	0.443
ENSAPEP00000002067	CLUL1	ENSAPEP00000002067	ENSAPEP00000020965	DAB adaptor protein 2.	Clusterin; Belongs to the clusterin family.	0.458
ENSAPEP00000002067	ENSAPEP00000003909	ENSAPEP00000002067	ENSAPEP00000003909	DAB adaptor protein 2.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.	0.611
ENSAPEP00000002067	ENSAPEP00000004296	ENSAPEP00000002067	ENSAPEP00000004296	DAB adaptor protein 2.	Low density lipoprotein receptor adaptor protein 1a.	0.860
ENSAPEP00000002067	ENSAPEP00000009387	ENSAPEP00000002067	ENSAPEP00000009387	DAB adaptor protein 2.	Clusterin; Belongs to the clusterin family.	0.458
ENSAPEP00000002067	ENSAPEP00000011061	ENSAPEP00000002067	ENSAPEP00000011061	DAB adaptor protein 2.	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.	0.611
ENSAPEP00000002067	ENSAPEP00000026312	ENSAPEP00000002067	ENSAPEP00000026312	DAB adaptor protein 2.	Low density lipoprotein receptor adaptor protein 1b.	0.880
ENSAPEP00000002067	ENSAPEP00000034178	ENSAPEP00000002067	ENSAPEP00000034178	DAB adaptor protein 2.	Clusterin; Belongs to the clusterin family.	0.458
ENSAPEP00000002373	CDC42	ENSAPEP00000002373	ENSAPEP00000028432	Uncharacterized protein.	Cell division cycle 42.	0.770