(41 nodes) Autonomic nervous system development network (Amphiprion percula)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000009869	Gastrulation brain homeobox 2. (339 aa)
	ENSAPEP00000001631	Uncharacterized protein. (155 aa)
	ENSAPEP00000001716	Uncharacterized protein. (126 aa)
	ENSAPEP00000001860	Nicalin. (577 aa)
	ENSAPEP00000004725	Homeobox domain-containing protein. (307 aa)
	ENSAPEP00000005342	Phosphatase and actin regulator 4a. (1130 aa)
	ENSAPEP00000006932	Heart and neural crest derivatives expressed 2. (225 aa)
	ENSAPEP00000007042	Phosphatase and actin regulator. (557 aa)
	ENSAPEP00000007693	Mediator complex subunit 24. (985 aa)
	ENSAPEP00000009555	Kif1 binding protein. (635 aa)
	ENSAPEP00000010378	Neurofibromin 1b. (2763 aa)
	ENSAPEP00000013293	Neuropilin; Belongs to the neuropilin family. (876 aa)
	ENSAPEP00000013380	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (503 aa)
	ENSAPEP00000013808	Fibronectin 1a. (2237 aa)
	ENSAPEP00000013844	Fibronectin type-III domain-containing protein. (104 aa)
	ENSAPEP00000014195	H2.0-like homeo box 1 (Drosophila). (376 aa)
	ENSAPEP00000014257	Mab-21-like 1. (359 aa)
	ENSAPEP00000016151	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (682 aa)
	ENSAPEP00000017239	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (254 aa)
	ENSAPEP00000019028	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (808 aa)
	ENSAPEP00000019479	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	ENSAPEP00000023746	RAD21 cohesin complex component a. (632 aa)
	ENSAPEP00000023945	Uncharacterized protein. (188 aa)
	ENSAPEP00000023984	Phosphatase and actin regulator. (540 aa)
	ENSAPEP00000024658	Paired like homeobox 2A. (285 aa)
	ENSAPEP00000025969	RE1-silencing transcription factor. (911 aa)
	ENSAPEP00000026211	Phosphatase and actin regulator. (882 aa)
	RAD21	RAD21 cohesin complex component. (653 aa)
	ENSAPEP00000027189	Paired like homeobox 2Bb. (285 aa)
	ENSAPEP00000028661	Chromo domain-containing protein. (485 aa)
	ENSAPEP00000030542	Uncharacterized protein. (138 aa)
	ENSAPEP00000030806	Achaete-scute family bHLH transcription factor 1a. (200 aa)
	ENSAPEP00000031393	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (419 aa)
	ENSAPEP00000032243	Si:dkey-49n23.1; Belongs to the semaphorin family. (706 aa)
	ENSAPEP00000032326	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (699 aa)
	ENSAPEP00000032538	Aristaless related homeobox a. (467 aa)
	ENSAPEP00000033565	Mab-21-like 2. (359 aa)
	ENSAPEP00000033714	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (476 aa)
	ENSAPEP00000033728	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	ENSAPEP00000034258	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	ENSAPEP00000034872	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1109 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPEP00000004725	ENSAPEP00000006932	ENSAPEP00000004725	ENSAPEP00000006932	Homeobox domain-containing protein.	Heart and neural crest derivatives expressed 2.	0.424
ENSAPEP00000006932	ENSAPEP00000004725	ENSAPEP00000006932	ENSAPEP00000004725	Heart and neural crest derivatives expressed 2.	Homeobox domain-containing protein.	0.424
ENSAPEP00000006932	ENSAPEP00000024658	ENSAPEP00000006932	ENSAPEP00000024658	Heart and neural crest derivatives expressed 2.	Paired like homeobox 2A.	0.528
ENSAPEP00000006932	ENSAPEP00000027189	ENSAPEP00000006932	ENSAPEP00000027189	Heart and neural crest derivatives expressed 2.	Paired like homeobox 2Bb.	0.565
ENSAPEP00000010378	ENSAPEP00000034872	ENSAPEP00000010378	ENSAPEP00000034872	Neurofibromin 1b.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.480
ENSAPEP00000013293	ENSAPEP00000016151	ENSAPEP00000013293	ENSAPEP00000016151	Neuropilin; Belongs to the neuropilin family.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	0.621
ENSAPEP00000013293	ENSAPEP00000019028	ENSAPEP00000013293	ENSAPEP00000019028	Neuropilin; Belongs to the neuropilin family.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family.	0.442
ENSAPEP00000013293	ENSAPEP00000032243	ENSAPEP00000013293	ENSAPEP00000032243	Neuropilin; Belongs to the neuropilin family.	Si:dkey-49n23.1; Belongs to the semaphorin family.	0.442
ENSAPEP00000013293	ENSAPEP00000032326	ENSAPEP00000013293	ENSAPEP00000032326	Neuropilin; Belongs to the neuropilin family.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family.	0.621
ENSAPEP00000013293	ENSAPEP00000034872	ENSAPEP00000013293	ENSAPEP00000034872	Neuropilin; Belongs to the neuropilin family.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.475
ENSAPEP00000013380	ENSAPEP00000019479	ENSAPEP00000013380	ENSAPEP00000019479	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.843
ENSAPEP00000013380	ENSAPEP00000031393	ENSAPEP00000013380	ENSAPEP00000031393	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.897
ENSAPEP00000013380	ENSAPEP00000033714	ENSAPEP00000013380	ENSAPEP00000033714	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.899
ENSAPEP00000013380	ENSAPEP00000033728	ENSAPEP00000013380	ENSAPEP00000033728	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.858
ENSAPEP00000016151	ENSAPEP00000013293	ENSAPEP00000016151	ENSAPEP00000013293	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.621
ENSAPEP00000017239	ENSAPEP00000034872	ENSAPEP00000017239	ENSAPEP00000034872	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.975
ENSAPEP00000019028	ENSAPEP00000013293	ENSAPEP00000019028	ENSAPEP00000013293	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.442
ENSAPEP00000019479	ENSAPEP00000013380	ENSAPEP00000019479	ENSAPEP00000013380	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.843
ENSAPEP00000019479	ENSAPEP00000031393	ENSAPEP00000019479	ENSAPEP00000031393	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.	0.765
ENSAPEP00000019479	ENSAPEP00000033714	ENSAPEP00000019479	ENSAPEP00000033714	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.	0.765