(72 nodes) Negative regulation of immune response network (Amphiprion percula)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000028650	YTH N(6)-methyladenosine RNA binding protein 3. (603 aa)
	ENSAPEP00000001577	THO complex 1. (656 aa)
	ENSAPEP00000001859	Sulfhydryl oxidase. (196 aa)
	ENSAPEP00000002154	Peptidoglycan recognition protein 2. (482 aa)
	ENSAPEP00000002520	Ly1 antibody reactive homolog (mouse). (345 aa)
	OTOP1	Otopetrin 1. (596 aa)
	ENSAPEP00000003038	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	ENSAPEP00000004823	Granulin b. (841 aa)
	ENSAPEP00000005007	Proteasome subunit beta; Belongs to the peptidase T1B family. (258 aa)
	ENSAPEP00000005068	Tumor necrosis factor, alpha-induced protein 3. (825 aa)
	ENSAPEP00000005234	Si:ch211-203k16.3. (472 aa)
	ENSAPEP00000005552	Fibronectin type-III domain-containing protein. (265 aa)
	ENSAPEP00000005597	Aryl hydrocarbon receptor 1b. (910 aa)
	ENSAPEP00000005612	Aryl hydrocarbon receptor 2. (1025 aa)
	ENSAPEP00000006523	Aconitate decarboxylase 1. (484 aa)
	ENSAPEP00000006644	Adenosine deaminase RNA specific. (1338 aa)
	ENSAPEP00000006719	DEXH (Asp-Glu-X-His) box polypeptide 58. (681 aa)
	ENSAPEP00000007055	T-box transcription factor 21. (618 aa)
	ENSAPEP00000008410	Zinc finger CCCH-type containing 12A. (631 aa)
	ENSAPEP00000008590	Poly [ADP-ribose] polymerase. (1813 aa)
	ENSAPEP00000009283	Methyltransferase like 3; Belongs to the MT-A70-like family. (592 aa)
	ENSAPEP00000009660	Protein inhibitor of activated STAT, 4a. (497 aa)
	ENSAPEP00000010000	Protein tyrosine phosphatase receptor type C. (1264 aa)
	ENSAPEP00000010190	Interleukin 10. (187 aa)
	ENSAPEP00000010598	HD_domain domain-containing protein. (529 aa)
	ENSAPEP00000010618	SAM domain and HD domain 1. (626 aa)
	ENSAPEP00000010662	Arginase. (350 aa)
	ENSAPEP00000010756	NLR family member X1. (971 aa)
	ENSAPEP00000010798	Ring finger and CCCH-type domains 2. (1153 aa)
	ENSAPEP00000010989	CD59 molecule (CD59 blood group). (117 aa)
	ENSAPEP00000011998	Ring finger and CCCH-type domains 1b. (1132 aa)
	ENSAPEP00000013126	Si:dkey-175m17.7. (872 aa)
	ENSAPEP00000013381	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (73 aa)
	ENSAPEP00000014178	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
	ENSAPEP00000014195	H2.0-like homeo box 1 (Drosophila). (376 aa)
	ENSAPEP00000014401	Arginase. (339 aa)
	ENSAPEP00000014468	Insulin-like growth factor 2b. (215 aa)
	ENSAPEP00000015045	Fibrinogen C-terminal domain-containing protein. (216 aa)
	IL12B-2	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (355 aa)
	ENSAPEP00000018100	Cactin. (872 aa)
	ENSAPEP00000020104	Uncharacterized protein; Belongs to the MT-A70-like family. (406 aa)
	ENSAPEP00000020642	Immunoresponsive gene 1, like. (495 aa)
	ENSAPEP00000022313	Uncharacterized protein. (299 aa)
	ENSAPEP00000022362	TNFR-Cys domain-containing protein. (258 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (291 aa)
	ENSAPEP00000022447	Uncharacterized protein. (984 aa)
	ENSAPEP00000023184	Uncharacterized protein. (952 aa)
	ENSAPEP00000023856	Poly [ADP-ribose] polymerase. (538 aa)
	ENSAPEP00000024082	Uncharacterized protein. (313 aa)
	ENSAPEP00000024169	Si:ch211-157b11.8. (319 aa)
	ENSAPEP00000024832	YTH N(6)-methyladenosine RNA binding protein 2. (639 aa)
	ENSAPEP00000024946	Uncharacterized protein. (346 aa)
	ENSAPEP00000024957	Uncharacterized protein. (465 aa)
	ENSAPEP00000025434	Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family. (596 aa)
	ENSAPEP00000025563	Fibrinogen-like 2a. (508 aa)
	ENSAPEP00000028960	Inositol polyphosphate-5-phosphatase D. (1084 aa)
	ENSAPEP00000028972	G protein-coupled receptor 17. (338 aa)
	ENSAPEP00000029049	Uncharacterized protein. (803 aa)
	ENSAPEP00000030963	Uncharacterized protein. (118 aa)
	ENSAPEP00000031313	Uncharacterized protein. (574 aa)
	ENSAPEP00000032063	SAM domain, SH3 domain and nuclear localisation signals 1a. (546 aa)
	ENSAPEP00000032452	Uncharacterized protein. (384 aa)
	ENSAPEP00000033308	Uncharacterized protein. (285 aa)
	ENSAPEP00000033448	Tubulin tyrosine ligase-like family, member 12. (633 aa)
	ENSAPEP00000034171	Fibronectin type-III domain-containing protein. (389 aa)
	ENSAPEP00000034544	TRAF-type zinc finger domain containing 1. (577 aa)
	ENSAPEP00000034635	RAB guanine nucleotide exchange factor (GEF) 1, like. (507 aa)
	ENSAPEP00000034787	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	ENSAPEP00000029108	GRANULINS domain-containing protein. (142 aa)
	ENSAPEP00000029583	DC-STAMP domain containing 1. (440 aa)
	ENSAPEP00000030659	Si:dkey-206d17.12. (259 aa)
	ENSAPEP00000030718	Uncharacterized protein. (512 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPEP00000003038	ENSAPEP00000006719	ENSAPEP00000003038	ENSAPEP00000006719	Autophagy protein 5; Involved in autophagic vesicle formation.	DEXH (Asp-Glu-X-His) box polypeptide 58.	0.882
ENSAPEP00000003038	ENSAPEP00000010756	ENSAPEP00000003038	ENSAPEP00000010756	Autophagy protein 5; Involved in autophagic vesicle formation.	NLR family member X1.	0.750
ENSAPEP00000003038	ENSAPEP00000013381	ENSAPEP00000003038	ENSAPEP00000013381	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ENSAPEP00000005068	ENSAPEP00000008410	ENSAPEP00000005068	ENSAPEP00000008410	Tumor necrosis factor, alpha-induced protein 3.	Zinc finger CCCH-type containing 12A.	0.430
ENSAPEP00000005068	ENSAPEP00000030659	ENSAPEP00000005068	ENSAPEP00000030659	Tumor necrosis factor, alpha-induced protein 3.	Si:dkey-206d17.12.	0.430
ENSAPEP00000005234	ENSAPEP00000010000	ENSAPEP00000005234	ENSAPEP00000010000	Si:ch211-203k16.3.	Protein tyrosine phosphatase receptor type C.	0.423
ENSAPEP00000005552	ENSAPEP00000010190	ENSAPEP00000005552	ENSAPEP00000010190	Fibronectin type-III domain-containing protein.	Interleukin 10.	0.872
ENSAPEP00000005552	ENSAPEP00000030718	ENSAPEP00000005552	ENSAPEP00000030718	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.442
ENSAPEP00000005552	ENSAPEP00000034635	ENSAPEP00000005552	ENSAPEP00000034635	Fibronectin type-III domain-containing protein.	RAB guanine nucleotide exchange factor (GEF) 1, like.	0.442
ENSAPEP00000006523	ENSAPEP00000020642	ENSAPEP00000006523	ENSAPEP00000020642	Aconitate decarboxylase 1.	Immunoresponsive gene 1, like.	0.899
ENSAPEP00000006644	ENSAPEP00000006719	ENSAPEP00000006644	ENSAPEP00000006719	Adenosine deaminase RNA specific.	DEXH (Asp-Glu-X-His) box polypeptide 58.	0.442
ENSAPEP00000006644	ENSAPEP00000010598	ENSAPEP00000006644	ENSAPEP00000010598	Adenosine deaminase RNA specific.	HD_domain domain-containing protein.	0.446
ENSAPEP00000006644	ENSAPEP00000010618	ENSAPEP00000006644	ENSAPEP00000010618	Adenosine deaminase RNA specific.	SAM domain and HD domain 1.	0.446
ENSAPEP00000006719	ENSAPEP00000003038	ENSAPEP00000006719	ENSAPEP00000003038	DEXH (Asp-Glu-X-His) box polypeptide 58.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.882
ENSAPEP00000006719	ENSAPEP00000006644	ENSAPEP00000006719	ENSAPEP00000006644	DEXH (Asp-Glu-X-His) box polypeptide 58.	Adenosine deaminase RNA specific.	0.442
ENSAPEP00000006719	ENSAPEP00000008590	ENSAPEP00000006719	ENSAPEP00000008590	DEXH (Asp-Glu-X-His) box polypeptide 58.	Poly [ADP-ribose] polymerase.	0.506
ENSAPEP00000006719	ENSAPEP00000010756	ENSAPEP00000006719	ENSAPEP00000010756	DEXH (Asp-Glu-X-His) box polypeptide 58.	NLR family member X1.	0.460
ENSAPEP00000006719	ENSAPEP00000013381	ENSAPEP00000006719	ENSAPEP00000013381	DEXH (Asp-Glu-X-His) box polypeptide 58.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.883
ENSAPEP00000007055	ENSAPEP00000010000	ENSAPEP00000007055	ENSAPEP00000010000	T-box transcription factor 21.	Protein tyrosine phosphatase receptor type C.	0.404
ENSAPEP00000007055	ENSAPEP00000010190	ENSAPEP00000007055	ENSAPEP00000010190	T-box transcription factor 21.	Interleukin 10.	0.519