STRINGSTRING
ENSAPEP00000026234 ENSAPEP00000026234 ENSAPEP00000000388 ENSAPEP00000000388 ENSAPEP00000000472 ENSAPEP00000000472 ENSAPEP00000001674 ENSAPEP00000001674 PPP3R1 PPP3R1 CTSH CTSH ENSAPEP00000002681 ENSAPEP00000002681 ENSAPEP00000004424 ENSAPEP00000004424 ENSAPEP00000004443 ENSAPEP00000004443 ENSAPEP00000004950 ENSAPEP00000004950 ENSAPEP00000005428 ENSAPEP00000005428 ENSAPEP00000007060 ENSAPEP00000007060 ENSAPEP00000009048 ENSAPEP00000009048 ENSAPEP00000009841 ENSAPEP00000009841 ENSAPEP00000009869 ENSAPEP00000009869 ENSAPEP00000010179 ENSAPEP00000010179 ENSAPEP00000010190 ENSAPEP00000010190 ENSAPEP00000010682 ENSAPEP00000010682 ENSAPEP00000010862 ENSAPEP00000010862 ILK ILK TGFBR2 TGFBR2 ENSAPEP00000011991 ENSAPEP00000011991 ENSAPEP00000012313 ENSAPEP00000012313 ENSAPEP00000012761 ENSAPEP00000012761 ENSAPEP00000013368 ENSAPEP00000013368 ENSAPEP00000013377 ENSAPEP00000013377 TGFBR2-2 TGFBR2-2 ENSAPEP00000014067 ENSAPEP00000014067 ENSAPEP00000014406 ENSAPEP00000014406 ENSAPEP00000015179 ENSAPEP00000015179 ENSAPEP00000015418 ENSAPEP00000015418 ENSAPEP00000015519 ENSAPEP00000015519 ENSAPEP00000016809 ENSAPEP00000016809 ENSAPEP00000017239 ENSAPEP00000017239 SMAD4 SMAD4 ENSAPEP00000017861 ENSAPEP00000017861 ENSAPEP00000018106 ENSAPEP00000018106 ENSAPEP00000018117 ENSAPEP00000018117 ENSAPEP00000018133 ENSAPEP00000018133 ENSAPEP00000018221 ENSAPEP00000018221 ENSAPEP00000018428 ENSAPEP00000018428 ENSAPEP00000019479 ENSAPEP00000019479 ENSAPEP00000019768 ENSAPEP00000019768 ENSAPEP00000021219 ENSAPEP00000021219 ENSAPEP00000021379 ENSAPEP00000021379 ENSAPEP00000021899 ENSAPEP00000021899 ENSAPEP00000022033 ENSAPEP00000022033 ENSAPEP00000024070 ENSAPEP00000024070 ENSAPEP00000024392 ENSAPEP00000024392 ENSAPEP00000024478 ENSAPEP00000024478 ENSAPEP00000025198 ENSAPEP00000025198 ENSAPEP00000025330 ENSAPEP00000025330 ENSAPEP00000034958 ENSAPEP00000034958 ENSAPEP00000034841 ENSAPEP00000034841 ENSAPEP00000034837 ENSAPEP00000034837 SRF SRF ENSAPEP00000033941 ENSAPEP00000033941 ENSAPEP00000033728 ENSAPEP00000033728 ENSAPEP00000033265 ENSAPEP00000033265 ENSAPEP00000032811 ENSAPEP00000032811 ENSAPEP00000032738 ENSAPEP00000032738 SOX10 SOX10 ENSAPEP00000032046 ENSAPEP00000032046 ENSAPEP00000031543 ENSAPEP00000031543 ENSAPEP00000030483 ENSAPEP00000030483 ENSAPEP00000029905 ENSAPEP00000029905 ENSAPEP00000029854 ENSAPEP00000029854 ENSAPEP00000028983 ENSAPEP00000028983 ENSAPEP00000028607 ENSAPEP00000028607 ENSAPEP00000027803 ENSAPEP00000027803 ENSAPEP00000027025 ENSAPEP00000027025 ENSAPEP00000026905 ENSAPEP00000026905 ENSAPEP00000026747 ENSAPEP00000026747 ENSAPEP00000025404 ENSAPEP00000025404 ENSAPEP00000025773 ENSAPEP00000025773 ENSAPEP00000026046 ENSAPEP00000026046 ENSAPEP00000026631 ENSAPEP00000026631
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSAPEP00000026234MADS-box domain-containing protein. (498 aa)
ENSAPEP00000000388Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
ENSAPEP00000000472Serine peptidase inhibitor, Kunitz type 1 a. (503 aa)
ENSAPEP00000001674Sprouty homolog 1, antagonist of FGF signaling (Drosophila). (362 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (309 aa)
ENSAPEP00000002681Secreted frizzled-related protein 2. (301 aa)
ENSAPEP00000004424Growth regulating estrogen receptor binding 1. (1736 aa)
ENSAPEP00000004443SRY-box transcription factor 9b. (478 aa)
ENSAPEP00000004950Mothers against decapentaplegic homolog. (508 aa)
ENSAPEP00000005428Suppressor of cytokine signaling 3a. (206 aa)
ENSAPEP00000007060Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (138 aa)
ENSAPEP00000009048Transmembrane protein 59-like. (339 aa)
ENSAPEP00000009841NOTCH regulated ankyrin repeat protein a. (112 aa)
ENSAPEP00000009869Gastrulation brain homeobox 2. (339 aa)
ENSAPEP00000010179Androgen receptor. (759 aa)
ENSAPEP00000010190Interleukin 10. (187 aa)
ENSAPEP00000010682WT1 transcription factor a. (422 aa)
ENSAPEP00000010862WT1 transcription factor b. (413 aa)
ILKIntegrin linked kinase. (492 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa)
ENSAPEP00000011991Transcription factor 21. (173 aa)
ENSAPEP00000012313Cathepsin Z; Belongs to the peptidase C1 family. (303 aa)
ENSAPEP00000012761Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (468 aa)
ENSAPEP00000013368Peptidase S72 domain-containing protein. (910 aa)
ENSAPEP00000013377Timeless circadian clock. (1152 aa)
TGFBR2-2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (549 aa)
ENSAPEP00000014067Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ENSAPEP00000014406Uncharacterized protein. (691 aa)
ENSAPEP00000015179Bone morphogenetic protein 16. (477 aa)
ENSAPEP00000015418Transmembrane p24 trafficking protein 2. (207 aa)
ENSAPEP00000015519Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2028 aa)
ENSAPEP00000016809Colony stimulating factor 1b (macrophage). (266 aa)
ENSAPEP00000017239Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (254 aa)
SMAD4Mothers against decapentaplegic homolog. (503 aa)
ENSAPEP00000017861Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (296 aa)
ENSAPEP00000018106Sprouty RTK signaling antagonist 2. (353 aa)
ENSAPEP00000018117Fem-1 homolog b (C. elegans). (627 aa)
ENSAPEP00000018133Polycystic kidney disease 1a. (4595 aa)
ENSAPEP00000018221SRY-box transcription factor 10. (511 aa)
ENSAPEP00000018428Mothers against decapentaplegic homolog. (510 aa)
ENSAPEP00000019479Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ENSAPEP00000019768Lymphoid enhancer-binding factor 1. (362 aa)
ENSAPEP00000021219Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1827 aa)
ENSAPEP00000021379Transforming growth factor beta; Belongs to the TGF-beta family. (384 aa)
ENSAPEP00000021899NK3 homeobox 1. (194 aa)
ENSAPEP00000022033Bone morphogenetic protein 4. (403 aa)
ENSAPEP00000024070Mothers against decapentaplegic homolog. (615 aa)
ENSAPEP00000024392Secreted frizzled-related protein 2 like. (341 aa)
ENSAPEP00000024478Bone morphogenetic protein 2b. (416 aa)
ENSAPEP00000025198Low density lipoprotein receptor-related protein 5. (1640 aa)
ENSAPEP00000025330Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
ENSAPEP00000034958Uncharacterized protein. (569 aa)
ENSAPEP00000034841Low density lipoprotein receptor-related protein 6. (447 aa)
ENSAPEP00000034837Uncharacterized protein. (468 aa)
SRFSerum response factor. (602 aa)
ENSAPEP00000033941Hedgehog interacting protein. (698 aa)
ENSAPEP00000033728Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (447 aa)
ENSAPEP00000033265BTB (POZ) domain containing 7. (1121 aa)
ENSAPEP00000032811Suppressor of cytokine signaling 3. (228 aa)
ENSAPEP00000032738Dystroglycan 1. (879 aa)
SOX10SRY-box transcription factor 10. (500 aa)
ENSAPEP00000032046GOLD domain-containing protein. (113 aa)
ENSAPEP00000031543Integrin linked kinase. (452 aa)
ENSAPEP00000030483Endothelin 1. (178 aa)
ENSAPEP00000029905Seryl-tRNA synthetase. (516 aa)
ENSAPEP00000029854MKS transition zone complex subunit 1. (563 aa)
ENSAPEP00000028983Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (737 aa)
ENSAPEP00000028607Nuclear factor of activated T cells 4. (838 aa)
ENSAPEP00000027803Polycystic kidney disease 1b. (2913 aa)
ENSAPEP00000027025SRY-box transcription factor 9a. (501 aa)
ENSAPEP00000026905Uncharacterized protein. (217 aa)
ENSAPEP00000026747TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (589 aa)
ENSAPEP00000025404Cathepsin H; Belongs to the peptidase C1 family. (323 aa)
ENSAPEP00000025773Serine peptidase inhibitor, Kunitz type 1 b. (498 aa)
ENSAPEP00000026046Catenin, beta interacting protein 1. (81 aa)
ENSAPEP00000026631Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (153 aa)
Your Current Organism:
Amphiprion percula
NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.