(83 nodes) Positive regulation of small molecule metabolic process network (Amphiprion percula)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000027536	annotation not available (144 aa)
	ENSAPEP00000000123	Damage-specific DNA binding protein 1. (1140 aa)
	ENSAPEP00000000133	Nuclear receptor subfamily 1, group H, member 3. (461 aa)
	ENSAPEP00000000775	Uncharacterized protein. (531 aa)
	ENSAPEP00000000990	Zinc finger and BTB domain containing 20. (680 aa)
	ENSAPEP00000001230	ATP-binding cassette, sub-family G (WHITE), member 1. (636 aa)
	ENSAPEP00000001304	Malonyl-CoA decarboxylase. (498 aa)
	ENSAPEP00000001504	BEN domain containing 3. (820 aa)
	ENSAPEP00000002067	DAB adaptor protein 2. (582 aa)
	ENSAPEP00000002079	SREBF chaperone. (1357 aa)
	ENSAPEP00000002734	ATP-binding cassette, sub-family G (WHITE), member 4a. (639 aa)
	ENSAPEP00000003613	Lysophosphatidylglycerol acyltransferase 1. (372 aa)
	ENSAPEP00000004586	Uncharacterized protein. (563 aa)
	ENSAPEP00000005751	Citrate lyase beta like. (367 aa)
	ENSAPEP00000005936	Uncharacterized protein. (1540 aa)
	PPARG	Peroxisome proliferator activated receptor gamma. (567 aa)
	ENSAPEP00000007375	ABC transporter domain-containing protein. (652 aa)
	ENSAPEP00000008099	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (442 aa)
	ENSAPEP00000008701	Peroxiredoxin like 2C. (225 aa)
	ENSAPEP00000009415	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (392 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (469 aa)
	ENSAPEP00000010016	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	MTLN	Mitoregulin. (56 aa)
	ENSAPEP00000011219	Nuclear receptor subfamily 1, group d, member 1. (613 aa)
	ENSAPEP00000012264	Nuclear receptor subfamily 1, group H, member 5. (488 aa)
	ENSAPEP00000012481	Prostaglandin-endoperoxide synthase 2b. (608 aa)
	ENSAPEP00000013289	ATP-binding cassette, sub-family D (ALD), member 2. (737 aa)
	ENSAPEP00000013578	Neuronal calcium sensor 1a. (190 aa)
	ENSAPEP00000013592	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
	ENSAPEP00000013911	Sterol regulatory element binding transcription factor 1. (1177 aa)
	ENSAPEP00000014467	Nuclear receptor subfamily 1, group D, member 4b. (566 aa)
	ENSAPEP00000014468	Insulin-like growth factor 2b. (215 aa)
	ENSAPEP00000015546	Si:dkey-6n21.13; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	ENSAPEP00000016321	Interleukin-1; Belongs to the IL-1 family. (259 aa)
	ENSAPEP00000017739	Dimer_Tnp_hAT domain-containing protein. (551 aa)
	ENSAPEP00000018254	Non-specific serine/threonine protein kinase. (557 aa)
	ENSAPEP00000018848	Sterol regulatory element binding transcription factor 2. (1181 aa)
	ENSAPEP00000020611	Ig-like domain-containing protein. (230 aa)
	ENSAPEP00000020909	Peroxisome proliferator-activated receptor alpha a. (482 aa)
	P2RY6	Pyrimidinergic receptor P2Y6. (383 aa)
	ENSAPEP00000023121	Si:ch211-103a14.5. (189 aa)
	ENSAPEP00000023537	Uncharacterized protein. (539 aa)
	ENSAPEP00000025330	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
	ENSAPEP00000026077	Guanylate cyclase activator 1B. (197 aa)
	ENSAPEP00000026526	Phosphotyrosine interaction domain containing 1. (225 aa)
	ENSAPEP00000026631	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (153 aa)
	ENSAPEP00000027157	Peroxisome proliferator-activated receptor delta b. (439 aa)
	ENSAPEP00000027389	Uncharacterized protein. (144 aa)
	ENSAPEP00000027410	Uncharacterized protein. (128 aa)
	ENSAPEP00000027494	Uncharacterized protein. (106 aa)
	ENSAPEP00000027540	5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (492 aa)
	ENSAPEP00000027557	Uncharacterized protein. (133 aa)
	ENSAPEP00000027580	annotation not available (133 aa)
	ENSAPEP00000027588	annotation not available (144 aa)
	ENSAPEP00000027611	annotation not available (133 aa)
	ENSAPEP00000027632	Uncharacterized protein. (115 aa)
	ENSAPEP00000027648	Uncharacterized protein. (162 aa)
	ENSAPEP00000027664	Uncharacterized protein. (128 aa)
	ENSAPEP00000027682	annotation not available (133 aa)
	ENSAPEP00000027689	annotation not available (162 aa)
	ENSAPEP00000027715	Uncharacterized protein. (145 aa)
	ENSAPEP00000027722	annotation not available (162 aa)
	ENSAPEP00000027777	annotation not available (145 aa)
	ENSAPEP00000027802	annotation not available (133 aa)
	ENSAPEP00000027815	Uncharacterized protein. (115 aa)
	ENSAPEP00000027840	Uncharacterized protein. (146 aa)
	ENSAPEP00000027872	Si:ch211-220m17.4. (105 aa)
	ENSAPEP00000027913	Uncharacterized protein. (108 aa)
	ENSAPEP00000028003	Uncharacterized protein. (123 aa)
	ENSAPEP00000028032	Uncharacterized protein. (108 aa)
	ENSAPEP00000028095	annotation not available (123 aa)
	ENSAPEP00000028098	Guanylate cyclase activator 1A. (208 aa)
	ENSAPEP00000029175	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (565 aa)
	ENSAPEP00000029233	Apolipoprotein Ea. (260 aa)
	ENSAPEP00000029658	Guanylate cyclase activator 1d. (185 aa)
	ENSAPEP00000030051	Ig-like domain-containing protein. (231 aa)
	ENSAPEP00000030371	annotation not available (260 aa)
	ENSAPEP00000031817	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (816 aa)
	ENSAPEP00000032353	Non-specific serine/threonine protein kinase. (573 aa)
	ENSAPEP00000032867	Podocan. (593 aa)
	ENSAPEP00000034094	Uncharacterized protein. (235 aa)
	ENSAPEP00000034786	Sirtuin 1. (659 aa)
	ENSAPEP00000034803	Sirtuin 1. (695 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPEP00000000123	ENSAPEP00000020611	ENSAPEP00000000123	ENSAPEP00000020611	Damage-specific DNA binding protein 1.	Ig-like domain-containing protein.	0.497
ENSAPEP00000000123	ENSAPEP00000030051	ENSAPEP00000000123	ENSAPEP00000030051	Damage-specific DNA binding protein 1.	Ig-like domain-containing protein.	0.497
ENSAPEP00000000123	ENSAPEP00000034786	ENSAPEP00000000123	ENSAPEP00000034786	Damage-specific DNA binding protein 1.	Sirtuin 1.	0.502
ENSAPEP00000000123	ENSAPEP00000034803	ENSAPEP00000000123	ENSAPEP00000034803	Damage-specific DNA binding protein 1.	Sirtuin 1.	0.502
ENSAPEP00000000133	ENSAPEP00000001230	ENSAPEP00000000133	ENSAPEP00000001230	Nuclear receptor subfamily 1, group H, member 3.	ATP-binding cassette, sub-family G (WHITE), member 1.	0.632
ENSAPEP00000000133	ENSAPEP00000002734	ENSAPEP00000000133	ENSAPEP00000002734	Nuclear receptor subfamily 1, group H, member 3.	ATP-binding cassette, sub-family G (WHITE), member 4a.	0.468
ENSAPEP00000000133	ENSAPEP00000007375	ENSAPEP00000000133	ENSAPEP00000007375	Nuclear receptor subfamily 1, group H, member 3.	ABC transporter domain-containing protein.	0.468
ENSAPEP00000000133	ENSAPEP00000011219	ENSAPEP00000000133	ENSAPEP00000011219	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 1, group d, member 1.	0.405
ENSAPEP00000000133	ENSAPEP00000013911	ENSAPEP00000000133	ENSAPEP00000013911	Nuclear receptor subfamily 1, group H, member 3.	Sterol regulatory element binding transcription factor 1.	0.620
ENSAPEP00000000133	ENSAPEP00000014467	ENSAPEP00000000133	ENSAPEP00000014467	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 1, group D, member 4b.	0.405
ENSAPEP00000000133	ENSAPEP00000018848	ENSAPEP00000000133	ENSAPEP00000018848	Nuclear receptor subfamily 1, group H, member 3.	Sterol regulatory element binding transcription factor 2.	0.561
ENSAPEP00000000133	ENSAPEP00000020909	ENSAPEP00000000133	ENSAPEP00000020909	Nuclear receptor subfamily 1, group H, member 3.	Peroxisome proliferator-activated receptor alpha a.	0.430
ENSAPEP00000000133	ENSAPEP00000031817	ENSAPEP00000000133	ENSAPEP00000031817	Nuclear receptor subfamily 1, group H, member 3.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.853
ENSAPEP00000000133	ENSAPEP00000034786	ENSAPEP00000000133	ENSAPEP00000034786	Nuclear receptor subfamily 1, group H, member 3.	Sirtuin 1.	0.538
ENSAPEP00000000133	ENSAPEP00000034803	ENSAPEP00000000133	ENSAPEP00000034803	Nuclear receptor subfamily 1, group H, member 3.	Sirtuin 1.	0.538
ENSAPEP00000000133	PPARA	ENSAPEP00000000133	ENSAPEP00000009647	Nuclear receptor subfamily 1, group H, member 3.	Peroxisome proliferator-activated receptor alpha b.	0.634
ENSAPEP00000000133	PPARG	ENSAPEP00000000133	ENSAPEP00000006947	Nuclear receptor subfamily 1, group H, member 3.	Peroxisome proliferator activated receptor gamma.	0.756
ENSAPEP00000001230	ENSAPEP00000000133	ENSAPEP00000001230	ENSAPEP00000000133	ATP-binding cassette, sub-family G (WHITE), member 1.	Nuclear receptor subfamily 1, group H, member 3.	0.632
ENSAPEP00000001230	ENSAPEP00000018848	ENSAPEP00000001230	ENSAPEP00000018848	ATP-binding cassette, sub-family G (WHITE), member 1.	Sterol regulatory element binding transcription factor 2.	0.509
ENSAPEP00000001230	ENSAPEP00000034094	ENSAPEP00000001230	ENSAPEP00000034094	ATP-binding cassette, sub-family G (WHITE), member 1.	Uncharacterized protein.	0.738