(79 nodes) Regulation of peptide transport network (Amphiprion percula)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000025181	Fibrinogen beta chain. (494 aa)
	ENSAPEP00000022807	RBR-type E3 ubiquitin transferase. (490 aa)
	ENSAPEP00000021923	Mitochondrial calcium uniporter. (377 aa)
	ENSAPEP00000021904	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1. (522 aa)
	ENSAPEP00000021610	Synaptotagmin VIIb. (562 aa)
	ENSAPEP00000020057	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1a. (308 aa)
	CCN3	Cellular communication network factor 3. (350 aa)
	ENSAPEP00000019780	Hydroxyacyl-CoA dehydrogenase. (309 aa)
	ENSAPEP00000019733	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (331 aa)
	MCUB	Mitochondrial calcium uniporter dominant negative beta subunit. (333 aa)
	ENSAPEP00000018906	Ubiquinol-cytochrome c reductase complex assembly factor 2. (164 aa)
	ENSAPEP00000018869	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (310 aa)
	ENSAPEP00000018769	Acetoacetyl-CoA synthetase. (676 aa)
	ENSAPEP00000018198	Uncharacterized protein. (161 aa)
	ENSAPEP00000018187	Urotensin 1. (148 aa)
	ENSAPEP00000018035	Sirtuin 6. (349 aa)
	ENSAPEP00000017932	Kruppel like factor 7. (301 aa)
	ENSAPEP00000017783	Regulatory factor X, 3 (influences HLA class II expression). (723 aa)
	ENSAPEP00000017705	Protein interacting with prkca 1. (452 aa)
	FFAR4	Free fatty acid receptor 4. (345 aa)
	ENSAPEP00000016854	Ubiquitin-like domain-containing protein. (413 aa)
	ENSAPEP00000016807	Regulatory factor X, 6. (882 aa)
	ENSAPEP00000016321	Interleukin-1; Belongs to the IL-1 family. (259 aa)
	ENSAPEP00000016265	tRNA-binding domain-containing protein. (305 aa)
	ENSAPEP00000015322	Potassium inwardly-rectifying channel, subfamily J, member 11. (369 aa)
	ENSAPEP00000015232	Uncharacterized protein. (240 aa)
	ENSAPEP00000014799	Calpain 10; Belongs to the peptidase C2 family. (666 aa)
	ENSAPEP00000014467	Nuclear receptor subfamily 1, group D, member 4b. (566 aa)
	ENSAPEP00000023042	Uncharacterized protein. (227 aa)
	ENSAPEP00000013523	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (312 aa)
	ENSAPEP00000013464	PAS domain containing serine/threonine kinase. (846 aa)
	ENSAPEP00000013028	Phospholipase A2, group VI (cytosolic, calcium-independent). (801 aa)
	ENSAPEP00000012895	Uncharacterized protein. (234 aa)
	ENSAPEP00000028950	Corticotropin releasing hormone b. (168 aa)
	ENSAPEP00000028834	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (307 aa)
	ENSAPEP00000028490	Si:dkey-211g8.6. (306 aa)
	ENSAPEP00000028239	Pancreatic and duodenal homeobox 1. (276 aa)
	ENSAPEP00000026629	Nuclear receptor subfamily 0, group B, member 2a. (255 aa)
	ENSAPEP00000026204	Potassium inwardly-rectifying channel, subfamily J, member 8. (419 aa)
	ENSAPEP00000026128	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1b. (383 aa)
	ENSAPEP00000026060	MCU domain-containing protein. (315 aa)
	ENSAPEP00000026029	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
	ENSAPEP00000023575	High mobility group nucleosomal binding domain 3. (118 aa)
	ENSAPEP00000023447	Motilin_assoc domain-containing protein. (107 aa)
	ENSAPEP00000023182	Thyrotropin-releasing hormone. (277 aa)
	ENSAPEP00000012264	Nuclear receptor subfamily 1, group H, member 5. (488 aa)
	ENSAPEP00000011528	Midnolin. (544 aa)
	ENSAPEP00000011441	Synaptotagmin IXa. (490 aa)
	ENSAPEP00000011219	Nuclear receptor subfamily 1, group d, member 1. (613 aa)
	SYT9	Synaptotagmin 9. (508 aa)
	ENSAPEP00000010828	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (126 aa)
	ENSAPEP00000010016	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	ENSAPEP00000006557	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1156 aa)
	ENSAPEP00000006402	Nuclear receptor subfamily 0, group B, member 2b. (292 aa)
	ENSAPEP00000006322	Uncharacterized protein. (101 aa)
	ENSAPEP00000006287	NADH:ubiquinone oxidoreductase complex assembly factor 2. (175 aa)
	ENSAPEP00000006024	G_PROTEIN_RECEP_F1_2 domain-containing protein. (336 aa)
	ENSAPEP00000005792	Si:ch211-231m23.4. (279 aa)
	ENSAPEP00000000642	Chromogranin A. (372 aa)
	ENSAPEP00000001125	Baculoviral IAP repeat containing 5a. (142 aa)
	ENSAPEP00000001621	CRF domain-containing protein. (143 aa)
	ENSAPEP00000002880	C2cd2 like. (693 aa)
	ENSAPEP00000003008	Kruppel-like factor 7b. (309 aa)
	ENSAPEP00000004451	Uncharacterized protein. (184 aa)
	SLC35F5	Solute carrier family 35 member F5. (482 aa)
	ENSAPEP00000004927	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1108 aa)
	ENSAPEP00000005716	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
	ENSAPEP00000029439	BCL2 associated agonist of cell death b. (167 aa)
	ENSAPEP00000030264	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (250 aa)
	ENSAPEP00000030308	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
	ENSAPEP00000030318	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
	ENSAPEP00000031154	Transmembrane 7 superfamily member 3. (566 aa)
	ENSAPEP00000031155	Synaptotagmin VIIa. (498 aa)
	ENSAPEP00000031254	Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (592 aa)
	ENSAPEP00000032706	RabBD domain-containing protein. (117 aa)
	ENSAPEP00000032709	Rab_eff_C domain-containing protein. (523 aa)
	ENSAPEP00000033744	RabBD domain-containing protein. (111 aa)
	ENSAPEP00000033748	Rab_eff_C domain-containing protein. (623 aa)
	ENSAPEP00000034840	Proteasome 26S subunit, non-ATPase 9. (212 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPEP00000000642	ENSAPEP00000023447	ENSAPEP00000000642	ENSAPEP00000023447	Chromogranin A.	Motilin_assoc domain-containing protein.	0.538
ENSAPEP00000001125	ENSAPEP00000013464	ENSAPEP00000001125	ENSAPEP00000013464	Baculoviral IAP repeat containing 5a.	PAS domain containing serine/threonine kinase.	0.445
ENSAPEP00000001125	ENSAPEP00000034840	ENSAPEP00000001125	ENSAPEP00000034840	Baculoviral IAP repeat containing 5a.	Proteasome 26S subunit, non-ATPase 9.	0.679
ENSAPEP00000001621	ENSAPEP00000005716	ENSAPEP00000001621	ENSAPEP00000005716	CRF domain-containing protein.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.806
ENSAPEP00000001621	ENSAPEP00000018187	ENSAPEP00000001621	ENSAPEP00000018187	CRF domain-containing protein.	Urotensin 1.	0.907
ENSAPEP00000001621	ENSAPEP00000023182	ENSAPEP00000001621	ENSAPEP00000023182	CRF domain-containing protein.	Thyrotropin-releasing hormone.	0.461
ENSAPEP00000001621	ENSAPEP00000023447	ENSAPEP00000001621	ENSAPEP00000023447	CRF domain-containing protein.	Motilin_assoc domain-containing protein.	0.560
ENSAPEP00000001621	ENSAPEP00000026029	ENSAPEP00000001621	ENSAPEP00000026029	CRF domain-containing protein.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.806
ENSAPEP00000001621	ENSAPEP00000028950	ENSAPEP00000001621	ENSAPEP00000028950	CRF domain-containing protein.	Corticotropin releasing hormone b.	0.903
ENSAPEP00000004451	ENSAPEP00000014799	ENSAPEP00000004451	ENSAPEP00000014799	Uncharacterized protein.	Calpain 10; Belongs to the peptidase C2 family.	0.545
ENSAPEP00000005716	ENSAPEP00000001621	ENSAPEP00000005716	ENSAPEP00000001621	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	CRF domain-containing protein.	0.806
ENSAPEP00000005716	ENSAPEP00000018187	ENSAPEP00000005716	ENSAPEP00000018187	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urotensin 1.	0.787
ENSAPEP00000005716	ENSAPEP00000028950	ENSAPEP00000005716	ENSAPEP00000028950	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Corticotropin releasing hormone b.	0.806
ENSAPEP00000005792	ENSAPEP00000023447	ENSAPEP00000005792	ENSAPEP00000023447	Si:ch211-231m23.4.	Motilin_assoc domain-containing protein.	0.849
ENSAPEP00000005792	FFAR4	ENSAPEP00000005792	ENSAPEP00000017383	Si:ch211-231m23.4.	Free fatty acid receptor 4.	0.602
ENSAPEP00000006024	ENSAPEP00000018198	ENSAPEP00000006024	ENSAPEP00000018198	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.409
ENSAPEP00000006024	ENSAPEP00000023447	ENSAPEP00000006024	ENSAPEP00000023447	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Motilin_assoc domain-containing protein.	0.816
ENSAPEP00000006024	FFAR4	ENSAPEP00000006024	ENSAPEP00000017383	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Free fatty acid receptor 4.	0.416
ENSAPEP00000006287	ENSAPEP00000018906	ENSAPEP00000006287	ENSAPEP00000018906	NADH:ubiquinone oxidoreductase complex assembly factor 2.	Ubiquinol-cytochrome c reductase complex assembly factor 2.	0.504
ENSAPEP00000006322	ENSAPEP00000023447	ENSAPEP00000006322	ENSAPEP00000023447	Uncharacterized protein.	Motilin_assoc domain-containing protein.	0.624