(78 nodes) Nuclear hormone receptor network (Amphiprion percula)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPEP00000000133	Nuclear receptor subfamily 1, group H, member 3. (461 aa)
	NR2E3	Nuclear receptor subfamily 2 group E member 3. (437 aa)
	ENSAPEP00000000286	Uncharacterized protein. (485 aa)
	ENSAPEP00000000671	Nuclear receptor subfamily 1, group I, member 2. (439 aa)
	ENSAPEP00000001280	Uncharacterized protein. (433 aa)
	ENSAPEP00000001576	Nuclear receptor subfamily 4, group A, member 3. (601 aa)
	ENSAPEP00000002464	Uncharacterized protein. (435 aa)
	ENSAPEP00000002848	Hepatocyte nuclear factor 4, alpha. (454 aa)
	ENSAPEP00000003911	Nuclear receptor subfamily 2, group C, member 1. (610 aa)
	ENSAPEP00000004031	RAR-related orphan receptor C. (505 aa)
	ENSAPEP00000004246	Estrogen receptor 2b. (567 aa)
	ENSAPEP00000004594	Nuclear receptor subfamily 5, group A, member 2. (468 aa)
	ENSAPEP00000004597	Estrogen-related receptor gamma a. (460 aa)
	RARG	Retinoic acid receptor gamma. (510 aa)
	ENSAPEP00000005285	Nuclear receptor subfamily 1, group D, member 4a. (576 aa)
	ENSAPEP00000006402	Nuclear receptor subfamily 0, group B, member 2b. (292 aa)
	ENSAPEP00000006795	Vitamin D receptor b. (425 aa)
	PPARG	Peroxisome proliferator activated receptor gamma. (567 aa)
	ENSAPEP00000007327	Retinoic acid receptor, alpha a. (455 aa)
	ENSAPEP00000007756	Uncharacterized protein. (420 aa)
	ENSAPEP00000007781	Uncharacterized protein. (409 aa)
	ENSAPEP00000007833	RAR-related orphan receptor C a. (496 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (294 aa)
	ENSAPEP00000008904	Estrogen receptor 2a. (559 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (469 aa)
	RARB	Retinoic acid receptor beta. (443 aa)
	ENSAPEP00000009954	Thyroid hormone receptor beta. (509 aa)
	ENSAPEP00000009970	Nuclear receptor subfamily 1, group D, member 2b. (592 aa)
	ENSAPEP00000010016	Nuclear receptor subfamily 1, group H, member 4. (485 aa)
	ENSAPEP00000010171	Estrogen-related receptor gamma b. (460 aa)
	ENSAPEP00000010179	Androgen receptor. (759 aa)
	ENSAPEP00000010550	Nuclear receptor subfamily 2, group F, member 6b. (406 aa)
	ENSAPEP00000011219	Nuclear receptor subfamily 1, group d, member 1. (613 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (590 aa)
	ENSAPEP00000012264	Nuclear receptor subfamily 1, group H, member 5. (488 aa)
	ENSAPEP00000012982	Estrogen-related receptor alpha. (433 aa)
	ENSAPEP00000013910	Nuclear receptor subfamily 5, group A, member 5. (543 aa)
	ENSAPEP00000014406	Uncharacterized protein. (691 aa)
	ENSAPEP00000014416	Retinoic acid receptor, gamma b. (430 aa)
	ENSAPEP00000014467	Nuclear receptor subfamily 1, group D, member 4b. (566 aa)
	ENSAPEP00000016218	Uncharacterized protein. (420 aa)
	ENSAPEP00000016849	RAR-related orphan receptor B. (500 aa)
	ESRRB	Estrogen-related receptor beta. (454 aa)
	ENSAPEP00000017612	Progesterone receptor. (658 aa)
	ENSAPEP00000018292	RAR-related orphan receptor C b. (503 aa)
	ENSAPEP00000018471	Retinoid x receptor, beta b. (444 aa)
	ENSAPEP00000018845	NR LBD domain-containing protein. (261 aa)
	RXRB	Retinoid X receptor beta. (470 aa)
	ENSAPEP00000019745	Uncharacterized protein. (461 aa)
	ENSAPEP00000020102	Nuclear receptor subfamily 6, group A, member 1a. (460 aa)
	ENSAPEP00000020158	Nuclear receptor subfamily 5, group A, member 1a. (486 aa)
	ENSAPEP00000020909	Peroxisome proliferator-activated receptor alpha a. (482 aa)
	ENSAPEP00000021495	Retinoid X receptor, alpha a. (496 aa)
	ENSAPEP00000021777	Nuclear receptor subfamily 2, group E, member 1. (370 aa)
	ENSAPEP00000022107	Nuclear receptor subfamily 2, group F, member 6a. (405 aa)
	ENSAPEP00000023084	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (613 aa)
	ENSAPEP00000023283	Nuclear receptor subfamily 2, group F, member 2. (417 aa)
	ENSAPEP00000023380	Nuclear receptor subfamily 2, group C, member 2. (629 aa)
	ENSAPEP00000023828	Nuclear receptor subfamily 4, group A, member 2b. (600 aa)
	ENSAPEP00000024677	Nuclear receptor subfamily 2, group F, member 1a. (411 aa)
	NR3C1	Nuclear receptor subfamily 3 group C member 1. (792 aa)
	ENSAPEP00000026464	Uncharacterized protein. (582 aa)
	ENSAPEP00000026629	Nuclear receptor subfamily 0, group B, member 2a. (255 aa)
	ENSAPEP00000026667	Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor). (782 aa)
	ENSAPEP00000026771	RAR-related orphan receptor A, paralog a. (519 aa)
	ENSAPEP00000027157	Peroxisome proliferator-activated receptor delta b. (439 aa)
	ENSAPEP00000027349	Uncharacterized protein. (341 aa)
	THRA	Thyroid hormone receptor alpha. (416 aa)
	ENSAPEP00000027786	Uncharacterized protein. (441 aa)
	ENSAPEP00000028541	Nuclear receptor subfamily 2, group E, member 3. (411 aa)
	ENSAPEP00000029127	Estrogen-related receptor delta. (436 aa)
	ENSAPEP00000031885	Nuclear receptor subfamily 2, group F, member 5. (404 aa)
	ENSAPEP00000032282	Nuclear receptor subfamily 4, group A, member 1. (591 aa)
	ENSAPEP00000033368	Nuclear receptor subfamily 1, group D, member 2a. (600 aa)
	ENSAPEP00000033542	Uncharacterized protein. (484 aa)
	ENSAPEP00000033621	Nuclear receptor subfamily 3, group C, member 2. (994 aa)
	ENSAPEP00000034060	Hepatocyte nuclear factor 4, gamma. (422 aa)
	ENSAPEP00000034081	Uncharacterized protein. (465 aa)

Your Current Organism:

Amphiprion percula

NCBI taxonomy Id: 161767
Other names: A. percula, Picasso clownfish, orange clownfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPEP00000000133	ENSAPEP00000000671	ENSAPEP00000000133	ENSAPEP00000000671	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 1, group I, member 2.	0.579
ENSAPEP00000000133	ENSAPEP00000001576	ENSAPEP00000000133	ENSAPEP00000001576	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 4, group A, member 3.	0.418
ENSAPEP00000000133	ENSAPEP00000002848	ENSAPEP00000000133	ENSAPEP00000002848	Nuclear receptor subfamily 1, group H, member 3.	Hepatocyte nuclear factor 4, alpha.	0.514
ENSAPEP00000000133	ENSAPEP00000004594	ENSAPEP00000000133	ENSAPEP00000004594	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 5, group A, member 2.	0.573
ENSAPEP00000000133	ENSAPEP00000005285	ENSAPEP00000000133	ENSAPEP00000005285	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 1, group D, member 4a.	0.888
ENSAPEP00000000133	ENSAPEP00000006402	ENSAPEP00000000133	ENSAPEP00000006402	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 0, group B, member 2b.	0.590
ENSAPEP00000000133	ENSAPEP00000007781	ENSAPEP00000000133	ENSAPEP00000007781	Nuclear receptor subfamily 1, group H, member 3.	Uncharacterized protein.	0.509
ENSAPEP00000000133	ENSAPEP00000009954	ENSAPEP00000000133	ENSAPEP00000009954	Nuclear receptor subfamily 1, group H, member 3.	Thyroid hormone receptor beta.	0.506
ENSAPEP00000000133	ENSAPEP00000009970	ENSAPEP00000000133	ENSAPEP00000009970	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 1, group D, member 2b.	0.888
ENSAPEP00000000133	ENSAPEP00000011219	ENSAPEP00000000133	ENSAPEP00000011219	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 1, group d, member 1.	0.405
ENSAPEP00000000133	ENSAPEP00000013910	ENSAPEP00000000133	ENSAPEP00000013910	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 5, group A, member 5.	0.532
ENSAPEP00000000133	ENSAPEP00000014467	ENSAPEP00000000133	ENSAPEP00000014467	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 1, group D, member 4b.	0.405
ENSAPEP00000000133	ENSAPEP00000018471	ENSAPEP00000000133	ENSAPEP00000018471	Nuclear receptor subfamily 1, group H, member 3.	Retinoid x receptor, beta b.	0.971
ENSAPEP00000000133	ENSAPEP00000019745	ENSAPEP00000000133	ENSAPEP00000019745	Nuclear receptor subfamily 1, group H, member 3.	Uncharacterized protein.	0.474
ENSAPEP00000000133	ENSAPEP00000020158	ENSAPEP00000000133	ENSAPEP00000020158	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 5, group A, member 1a.	0.573
ENSAPEP00000000133	ENSAPEP00000020909	ENSAPEP00000000133	ENSAPEP00000020909	Nuclear receptor subfamily 1, group H, member 3.	Peroxisome proliferator-activated receptor alpha a.	0.430
ENSAPEP00000000133	ENSAPEP00000021495	ENSAPEP00000000133	ENSAPEP00000021495	Nuclear receptor subfamily 1, group H, member 3.	Retinoid X receptor, alpha a.	0.971
ENSAPEP00000000133	ENSAPEP00000023828	ENSAPEP00000000133	ENSAPEP00000023828	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 4, group A, member 2b.	0.418
ENSAPEP00000000133	ENSAPEP00000026464	ENSAPEP00000000133	ENSAPEP00000026464	Nuclear receptor subfamily 1, group H, member 3.	Uncharacterized protein.	0.418
ENSAPEP00000000133	ENSAPEP00000026629	ENSAPEP00000000133	ENSAPEP00000026629	Nuclear receptor subfamily 1, group H, member 3.	Nuclear receptor subfamily 0, group B, member 2a.	0.590