STRINGSTRING
AJT42753.1 AJT42753.1 AJT40555.1 AJT40555.1 panB panB dxs dxs ribB ribB ribA ribA ribH ribH AJT40833.1 AJT40833.1 pdxS pdxS pdxT pdxT AJT40996.1 AJT40996.1 thiC thiC thiL thiL AJT41485.1 AJT41485.1 kbl kbl thiG thiG AJT41541.1 AJT41541.1 AJT41570.1 AJT41570.1 AJT41601.1 AJT41601.1 AJT41646.1 AJT41646.1 AJT41648.1 AJT41648.1 bioD bioD AJT41794.1 AJT41794.1 AJT43031.1 AJT43031.1 bioB bioB AJT41836.1 AJT41836.1 AJT42004.1 AJT42004.1 AJT42041.1 AJT42041.1 panD panD AJT42171.1 AJT42171.1 thiM thiM thiE thiE AJT43123.1 AJT43123.1 AJT42355.1 AJT42355.1 AJT42356.1 AJT42356.1 AJT42357.1 AJT42357.1 panC panC AJT42482.1 AJT42482.1 AJT42647.1 AJT42647.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJT42753.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
AJT40555.1Riboflavin kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (321 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (288 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (661 aa)
ribBHypothetical protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (213 aa)
ribAGTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (218 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (153 aa)
AJT40833.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (302 aa)
pdxTGlutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (215 aa)
AJT40996.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (595 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (346 aa)
AJT41485.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
kbl2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (398 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa)
AJT41541.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
AJT41570.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AJT41601.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AJT41646.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
AJT41648.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
bioDHypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa)
AJT41794.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AJT43031.1Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (352 aa)
AJT41836.1Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
AJT42004.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AJT42041.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
panDAspartate 1-decarboxylase subunit alpha; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (138 aa)
AJT42171.13-demethylubiquinone-9 3-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (217 aa)
AJT43123.1Hydroxymethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
AJT42355.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (310 aa)
AJT42356.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa)
AJT42357.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (294 aa)
AJT42482.1FAD-linked oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
AJT42647.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (375 aa)
Your Current Organism:
Psychromicrobium lacuslunae
NCBI taxonomy Id: 1618207
Other names: Arthrobacter sp. IHBB 11108, JCM 31143, KACC 19070, MCC 2780, MTCC 12460, P. lacuslunae, strain IHBB 11108
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