(14 nodes) DEAD-like helicases superfamily network (Psychromicrobium lacuslunae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJT42644.1	Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
	AJT42117.1	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
	AJT40346.1	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1054 aa)
	mfd	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1204 aa)
	AJT40595.1	ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (681 aa)
	uvrB	Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (693 aa)
	AJT40846.1	DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (845 aa)
	AJT40939.1	RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (948 aa)
	AJT42909.1	DEAD/DEAH box helicase; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1031 aa)
	AJT41241.1	ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. (742 aa)
	AJT41543.1	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (555 aa)
	deaD	Cold-shock protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (645 aa)
	AJT41945.1	Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (777 aa)
	AJT43081.1	DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa)

Your Current Organism:

Psychromicrobium lacuslunae

NCBI taxonomy Id: 1618207
Other names: Arthrobacter sp. IHBB 11108, JCM 31143, KACC 19070, MCC 2780, MTCC 12460, P. lacuslunae, strain IHBB 11108

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJT40346.1	AJT40595.1	UM93_00035	UM93_01880	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.731
AJT40346.1	AJT41543.1	UM93_00035	UM93_08510	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.	0.719
AJT40346.1	AJT42117.1	UM93_00035	UM93_12475	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.722
AJT40346.1	AJT42644.1	UM93_00035	UM93_16305	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.593
AJT40346.1	AJT43081.1	UM93_00035	UM93_11595	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.719
AJT40346.1	deaD	UM93_00035	UM93_10320	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cold-shock protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	0.719
AJT40595.1	AJT40346.1	UM93_01880	UM93_00035	ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.731
AJT40595.1	AJT42117.1	UM93_01880	UM93_12475	ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.550
AJT40595.1	AJT42644.1	UM93_01880	UM93_16305	ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.830
AJT41241.1	uvrB	UM93_06375	UM93_03730	ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.487
AJT41543.1	AJT40346.1	UM93_08510	UM93_00035	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.719
AJT41543.1	AJT42117.1	UM93_08510	UM93_12475	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.533
AJT42117.1	AJT40346.1	UM93_12475	UM93_00035	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.722
AJT42117.1	AJT40595.1	UM93_12475	UM93_01880	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.550
AJT42117.1	AJT41543.1	UM93_12475	UM93_08510	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.	0.533
AJT42117.1	AJT43081.1	UM93_12475	UM93_11595	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.677
AJT42117.1	deaD	UM93_12475	UM93_10320	ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cold-shock protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	0.957
AJT42644.1	AJT40346.1	UM93_16305	UM93_00035	Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.593
AJT42644.1	AJT40595.1	UM93_16305	UM93_01880	Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.830
AJT42644.1	AJT42909.1	UM93_16305	UM93_05585	Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DEAD/DEAH box helicase; Subunit R is required for both nuclease and ATPase activities, but not for modification.	0.426