(25 nodes) Butanoate metabolism network (Psychromicrobium lacuslunae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJT40375.1	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
	AJT40376.1	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
	AJT40377.1	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
	AJT40378.1	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
	AJT40430.1	Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (492 aa)
	AJT40529.1	succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
	AJT40530.1	succinyl-CoA:3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	AJT42872.1	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa)
	AJT41197.1	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
	AJT41266.1	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
	AJT42932.1	Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
	AJT41269.1	Arylmalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
	AJT42942.1	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
	AJT41744.1	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	AJT41855.1	4-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
	AJT41913.1	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	AJT41914.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
	AJT41971.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
	AJT43079.1	3-hydroxyisobutyryl-CoA hydrolase; Catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
	AJT42450.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (721 aa)
	AJT42451.1	acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
	AJT42477.1	3-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
	AJT42579.1	enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
	AJT42588.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
	AJT42690.1	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (561 aa)

Your Current Organism:

Psychromicrobium lacuslunae

NCBI taxonomy Id: 1618207
Other names: Arthrobacter sp. IHBB 11108, JCM 31143, KACC 19070, MCC 2780, MTCC 12460, P. lacuslunae, strain IHBB 11108

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJT40375.1	AJT40376.1	UM93_00260	UM93_00265	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40375.1	AJT40377.1	UM93_00260	UM93_00270	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40375.1	AJT40378.1	UM93_00260	UM93_00275	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40375.1	AJT40430.1	UM93_00260	UM93_00645	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	0.916
AJT40375.1	AJT41197.1	UM93_00260	UM93_06100	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40375.1	AJT41269.1	UM93_00260	UM93_06555	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Arylmalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AJT40375.1	AJT41913.1	UM93_00260	UM93_11020	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.417
AJT40376.1	AJT40375.1	UM93_00265	UM93_00260	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40376.1	AJT40377.1	UM93_00265	UM93_00270	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40376.1	AJT40378.1	UM93_00265	UM93_00275	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40376.1	AJT40430.1	UM93_00265	UM93_00645	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	0.920
AJT40376.1	AJT41197.1	UM93_00265	UM93_06100	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
AJT40376.1	AJT41269.1	UM93_00265	UM93_06555	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	Arylmalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AJT40377.1	AJT40375.1	UM93_00270	UM93_00260	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40377.1	AJT40376.1	UM93_00270	UM93_00265	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40377.1	AJT40378.1	UM93_00270	UM93_00275	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AJT40377.1	AJT40430.1	UM93_00270	UM93_00645	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.	0.903
AJT40377.1	AJT41197.1	UM93_00270	UM93_06100	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
AJT40377.1	AJT41269.1	UM93_00270	UM93_06555	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Arylmalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AJT40378.1	AJT40375.1	UM93_00275	UM93_00260	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999