STRINGSTRING
ARJ03809.1 ARJ03809.1 ARJ03920.1 ARJ03920.1 ARJ03928.1 ARJ03928.1 ARJ03999.1 ARJ03999.1 ARJ04020.1 ARJ04020.1 ARJ04076.1 ARJ04076.1 ARJ04326.1 ARJ04326.1 serS serS ARJ07168.1 ARJ07168.1 upp upp ARJ04379.1 ARJ04379.1 ARJ04405.1 ARJ04405.1 ARJ04436.1 ARJ04436.1 ARJ04473.1 ARJ04473.1 ARJ04504.1 ARJ04504.1 tilS tilS ftsH ftsH folE folE B5808_04170 B5808_04170 ARJ04509.1 ARJ04509.1 ARJ04510.1 ARJ04510.1 ARJ04511.1 ARJ04511.1 ARJ04512.1 ARJ04512.1 ARJ04513.1 ARJ04513.1 ARJ04521.1 ARJ04521.1 cpdA cpdA ARJ04561.1 ARJ04561.1 thyA thyA guaB guaB ARJ04653.1 ARJ04653.1 guaA guaA purN purN purH purH purU purU glyA glyA folD folD cysS cysS ARJ04732.1 ARJ04732.1 apt apt cpdA-2 cpdA-2 dapA dapA dapF dapF hisC hisC hisB hisB hisH hisH hisA hisA ARJ04971.1 ARJ04971.1 argC argC argJ argJ argB argB argD argD ARJ04977.1 ARJ04977.1 argH argH ARJ04979.1 ARJ04979.1 ARJ05012.1 ARJ05012.1 ARJ05068.1 ARJ05068.1 ARJ05069.1 ARJ05069.1 ARJ05070.1 ARJ05070.1 ARJ05101.1 ARJ05101.1 ARJ05102.1 ARJ05102.1 def def ARJ05134.1 ARJ05134.1 hisD hisD pyrD pyrD trpD trpD ARJ07286.1 ARJ07286.1 ARJ05193.1 ARJ05193.1 rlmN rlmN ARJ05335.1 ARJ05335.1 lgt lgt trpA trpA trpB trpB ARJ05385.1 ARJ05385.1 ARJ05386.1 ARJ05386.1 trpE trpE hisI hisI hisF hisF hisG hisG hisE hisE ARJ05394.1 ARJ05394.1 ARJ05395.1 ARJ05395.1 fmt fmt priA priA metK metK gmk gmk ARJ05401.1 ARJ05401.1 carB carB carA carA ARJ05403.1 ARJ05403.1 pyrC pyrC pyrB pyrB pyrR pyrR ARJ05407.1 ARJ05407.1 aroQ aroQ aroB aroB aroK aroK aroC aroC ARJ05414.1 ARJ05414.1 mltG mltG ARJ05416.1 ARJ05416.1 alaS alaS ARJ05418.1 ARJ05418.1 ARJ05419.1 ARJ05419.1 dut dut dapB dapB aspA aspA thrB thrB ARJ07314.1 ARJ07314.1 ARJ05594.1 ARJ05594.1 lysA lysA ARJ05613.1 ARJ05613.1 metXA metXA ARJ05623.1 ARJ05623.1 aroA aroA ARJ07322.1 ARJ07322.1 ARJ05639.1 ARJ05639.1 ARJ05640.1 ARJ05640.1 rph rph murI murI ARJ05659.1 ARJ05659.1 ARJ05704.1 ARJ05704.1 dapD dapD ARJ05707.1 ARJ05707.1 ARJ05751.1 ARJ05751.1 ARJ05780.1 ARJ05780.1 ARJ05797.1 ARJ05797.1 ARJ05831.1 ARJ05831.1 ARJ05938.1 ARJ05938.1 ahcY ahcY purE purE purK purK ARJ06025.1 ARJ06025.1 ARJ06030.1 ARJ06030.1 ARJ06033.1 ARJ06033.1 rihB rihB ARJ06035.1 ARJ06035.1 ARJ06036.1 ARJ06036.1 ribH ribH ribA ribA ARJ06057.1 ARJ06057.1 ARJ06058.1 ARJ06058.1 tmk tmk ARJ06080.1 ARJ06080.1 asd asd ARJ06154.1 ARJ06154.1 ARJ06199.1 ARJ06199.1 ARJ06200.1 ARJ06200.1 B5808_13950 B5808_13950 ARJ06202.1 ARJ06202.1 ARJ06203.1 ARJ06203.1 ARJ06215.1 ARJ06215.1 ARJ06223.1 ARJ06223.1 argG argG purD purD purC purC aroQ-2 aroQ-2 purM purM purF purF psuG psuG ARJ06394.1 ARJ06394.1 purS purS purQ purQ ARJ07433.1 ARJ07433.1 ARJ06467.1 ARJ06467.1 ARJ06506.1 ARJ06506.1 ARJ07435.1 ARJ07435.1 ARJ06527.1 ARJ06527.1 ARJ06596.1 ARJ06596.1 purL purL ARJ06603.1 ARJ06603.1 purA purA ARJ06620.1 ARJ06620.1 pyrE pyrE ARJ06686.1 ARJ06686.1 ARJ06769.1 ARJ06769.1 ARJ06772.1 ARJ06772.1 ARJ06921.1 ARJ06921.1 trpF trpF ARJ07001.1 ARJ07001.1 ARJ07005.1 ARJ07005.1 ARJ07011.1 ARJ07011.1 dcd dcd pat pat ARJ07062.1 ARJ07062.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ARJ03809.1Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
ARJ03920.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa)
ARJ03928.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
ARJ03999.1Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
ARJ04020.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ARJ04076.1Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
ARJ04326.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa)
ARJ07168.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (210 aa)
ARJ04379.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
ARJ04405.1Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
ARJ04436.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
ARJ04473.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
ARJ04504.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa)
tilStRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (355 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (670 aa)
folEHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
B5808_04170Dihydropteroate synthase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (162 aa)
ARJ04509.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
ARJ04510.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
ARJ04511.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
ARJ04512.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
ARJ04513.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
ARJ04521.1N-acetylglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (173 aa)
cpdAPhosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (312 aa)
ARJ04561.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (159 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (268 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (499 aa)
ARJ04653.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (537 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (197 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (313 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (455 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (472 aa)
ARJ04732.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (371 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (236 aa)
cpdA-2Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (297 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (325 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (293 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (360 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa)
hisA1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
ARJ04971.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (266 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (348 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (386 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (302 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (384 aa)
ARJ04977.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (311 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
ARJ04979.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA glycosylase MPG family. (209 aa)
ARJ05012.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
ARJ05068.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
ARJ05069.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
ARJ05070.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (293 aa)
ARJ05101.1Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
ARJ05102.1Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (163 aa)
ARJ05134.13-deoxy-7-phosphoheptulonate synthase class II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (460 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (436 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (348 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (350 aa)
ARJ07286.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
ARJ05193.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
rlmN23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (399 aa)
ARJ05335.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (340 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (260 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (410 aa)
ARJ05385.1Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (257 aa)
ARJ05386.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (505 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (123 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (279 aa)
hisEphosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
ARJ05394.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (134 aa)
ARJ05395.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (477 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (305 aa)
priAHypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (697 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (302 aa)
ARJ05401.1Orotidine-5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1094 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (382 aa)
ARJ05403.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (172 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (446 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (316 aa)
pyrRBifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (180 aa)
ARJ05407.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (267 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa)
aroKHypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (189 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (399 aa)
ARJ05414.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
mltGHypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (394 aa)
ARJ05416.1Holliday junction resolvase RuvX; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (165 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (885 aa)
ARJ05418.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
ARJ05419.1DUF948 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (165 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (271 aa)
aspAAspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (312 aa)
ARJ07314.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (361 aa)
ARJ05594.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (485 aa)
ARJ05613.1Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (403 aa)
ARJ05623.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (452 aa)
ARJ07322.1Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
ARJ05639.1Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
ARJ05640.1Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (198 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (250 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (281 aa)
ARJ05659.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
ARJ05704.1Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (319 aa)
ARJ05707.1Succinyldiaminopimelate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
ARJ05751.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
ARJ05780.1YfcE family phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
ARJ05797.1Nucleoside triphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
ARJ05831.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ARJ05938.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (493 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (155 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (405 aa)
ARJ06025.1Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (277 aa)
ARJ06030.1Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
ARJ06033.1Adenosylhomocysteinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
rihBRibonucleoside hydrolase; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
ARJ06035.1Thymidine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
ARJ06036.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (140 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (168 aa)
ribABifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (409 aa)
ARJ06057.1Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
ARJ06058.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (358 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (211 aa)
ARJ06080.1Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (372 aa)
ARJ06154.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (444 aa)
ARJ06199.1Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (326 aa)
ARJ06200.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (753 aa)
B5808_13950Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
ARJ06202.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
ARJ06203.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
ARJ06215.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (461 aa)
ARJ06223.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (480 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (452 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (317 aa)
aroQ-2Hypothetical protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (485 aa)
psuGPseudouridine-5-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (301 aa)
ARJ06394.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2317 aa)
purSPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (89 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (232 aa)
ARJ07433.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
ARJ06467.1Cysteine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (312 aa)
ARJ06506.1Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
ARJ07435.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
ARJ06527.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
ARJ06596.1Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (465 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (791 aa)
ARJ06603.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa)
ARJ06620.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (182 aa)
ARJ06686.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
ARJ06769.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (310 aa)
ARJ06772.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (144 aa)
ARJ06921.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
trpFHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (202 aa)
ARJ07001.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
ARJ07005.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
ARJ07011.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
dcddCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (201 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (361 aa)
ARJ07062.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
Your Current Organism:
Cnuibacter physcomitrellae
NCBI taxonomy Id: 1619308
Other names: C. physcomitrellae, CGMCC 1.15041, Cnuibacter physcomitrellae Zhou et al. 2016, DSM 29843, Microbacteriaceae bacterium XA, strain XA
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