STRINGSTRING
ARJ07381.1 ARJ07381.1 ARJ03829.1 ARJ03829.1 ARJ07094.1 ARJ07094.1 ARJ07097.1 ARJ07097.1 ARJ03914.1 ARJ03914.1 ARJ03971.1 ARJ03971.1 ARJ04017.1 ARJ04017.1 ARJ04038.1 ARJ04038.1 ARJ04130.1 ARJ04130.1 ARJ04445.1 ARJ04445.1 thiE thiE guaB guaB ARJ04653.1 ARJ04653.1 ARJ04941.1 ARJ04941.1 dapA dapA hisA hisA deoC deoC leuA leuA ARJ05024.1 ARJ05024.1 ARJ05030.1 ARJ05030.1 ARJ05129.1 ARJ05129.1 ARJ05134.1 ARJ05134.1 pyrD pyrD rlmN rlmN tal tal tpiA tpiA ARJ05382.1 ARJ05382.1 trpA trpA ARJ05385.1 ARJ05385.1 hisF hisF ARJ05393.1 ARJ05393.1 ARJ05401.1 ARJ05401.1 pdxS pdxS ARJ05532.1 ARJ05532.1 leuA-2 leuA-2 ARJ05623.1 ARJ05623.1 ARJ05643.1 ARJ05643.1 ARJ05735.1 ARJ05735.1 ARJ05763.1 ARJ05763.1 ARJ05778.1 ARJ05778.1 moaA moaA ARJ06247.1 ARJ06247.1 ARJ07414.1 ARJ07414.1 ARJ06338.1 ARJ06338.1 ARJ06608.1 ARJ06608.1 ARJ06637.1 ARJ06637.1 ARJ06688.1 ARJ06688.1 ARJ06769.1 ARJ06769.1 trpF trpF ARJ07004.1 ARJ07004.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARJ07381.17,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG; Derived by automated computational analysis using gene prediction method: Protein Homology. (783 aa)
ARJ03829.1Lactate 2-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
ARJ07094.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
ARJ07097.1Fructose bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
ARJ03914.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
ARJ03971.13-keto-5-aminohexanoate cleavage protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ARJ04017.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
ARJ04038.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (333 aa)
ARJ04130.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
ARJ04445.1Alpha-hydroxy-acid oxidizing enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (217 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (499 aa)
ARJ04653.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
ARJ04941.1Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (406 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (325 aa)
hisA1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (223 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (580 aa)
ARJ05024.1Mycofactocin radical SAM maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
ARJ05030.1Alpha-hydroxy-acid oxidizing enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
ARJ05129.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1137 aa)
ARJ05134.13-deoxy-7-phosphoheptulonate synthase class II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (460 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (348 aa)
rlmN23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (399 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (370 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (262 aa)
ARJ05382.1Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1526 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (260 aa)
ARJ05385.1Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (257 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
ARJ05393.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa)
ARJ05401.1Orotidine-5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
pdxSPyridoxal 5'-phosphate synthase lyase subunit PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (301 aa)
ARJ05532.1tRNA dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (394 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (588 aa)
ARJ05623.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
ARJ05643.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (432 aa)
ARJ05735.1Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (341 aa)
ARJ05763.1Ketose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
ARJ05778.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
moaAGTP 3',8-cyclase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (373 aa)
ARJ06247.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
ARJ07414.12-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
ARJ06338.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
ARJ06608.1Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (236 aa)
ARJ06637.1Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (285 aa)
ARJ06688.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
ARJ06769.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (310 aa)
trpFHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (202 aa)
ARJ07004.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
Your Current Organism:
Cnuibacter physcomitrellae
NCBI taxonomy Id: 1619308
Other names: C. physcomitrellae, CGMCC 1.15041, Cnuibacter physcomitrellae Zhou et al. 2016, DSM 29843, Microbacteriaceae bacterium XA, strain XA
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