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purK purK purE purE purB purB purT purT purF purF purC purC purM purM purN purN purL purL purH purH purD purD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Your Input:
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (356 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa)
purBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (392 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (505 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (237 aa)
purMPhosphoribosylaminoimidazole synthetase. (346 aa)
purNPhosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (212 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1296 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase. (529 aa)
purDPhosphoribosylamine-glycine ligase; Belongs to the GARS family. (426 aa)
Your Current Organism:
Erwinia gerundensis
NCBI taxonomy Id: 1619313
Other names: CCOS 903, CCOS:903, E. gerundensis, Erwinia gerundensis Rezzonico et al. 2016, Erwinia sp. 08-046A, Erwinia sp. 08-069A, Erwinia sp. 08-085C, Erwinia sp. 6-RJ-7B, Erwinia sp. EM406, Erwinia sp. EM436, Erwinia sp. EM477, Erwinia sp. EM486, Erwinia sp. EM573, Erwinia sp. EM595, Erwinia sp. EM603, Erwinia sp. KAZ28, LMG 28990, LMG:28990, Pantoea sp. EM486, Pantoea sp. EM595, Pantoea sp. P10QLC, Pantoea sp. P8SAA, strain EM595
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