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yhcM yhcM envC envC ftsN ftsN ftsE ftsE ftsL ftsL ftsI1 ftsI1 ftsW ftsW ftsQ ftsQ ftsZ ftsZ zapD zapD tolQ tolQ zapC zapC zipA zipA dapE dapE nlpD nlpD queE queE ftsI2 ftsI2 yraP yraP CUU25405.1 CUU25405.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yhcMPutative protein YhcM; Reduces the stability of FtsZ polymers in the presence of ATP. (381 aa)
envCMurein hydrolase activator EnvC. (462 aa)
ftsNHypothetical protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (299 aa)
ftsECell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. (222 aa)
ftsLCell division protein ftsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (106 aa)
ftsI1Division specific transpeptidase, penicillin-binding protein 3 re; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (588 aa)
ftsWCell division protein ftsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (404 aa)
ftsQCell division ftsQ-like protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (280 aa)
ftsZCell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (384 aa)
zapDCell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (246 aa)
tolQProtein tolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (225 aa)
zapCCell division protein ZapC; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (181 aa)
zipACell division zipA-like protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (331 aa)
dapEN-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa)
nlpDMurein hydrolase activator NlpD. (371 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (223 aa)
ftsI2Peptidoglycan synthetase ftsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (571 aa)
yraPPutative protein YraP. (190 aa)
CUU25405.1Hypothetical protein. (428 aa)
Your Current Organism:
Erwinia gerundensis
NCBI taxonomy Id: 1619313
Other names: CCOS 903, CCOS:903, E. gerundensis, Erwinia gerundensis Rezzonico et al. 2016, Erwinia sp. 08-046A, Erwinia sp. 08-069A, Erwinia sp. 08-085C, Erwinia sp. 6-RJ-7B, Erwinia sp. EM406, Erwinia sp. EM436, Erwinia sp. EM477, Erwinia sp. EM486, Erwinia sp. EM573, Erwinia sp. EM595, Erwinia sp. EM603, Erwinia sp. KAZ28, LMG 28990, LMG:28990, Pantoea sp. EM486, Pantoea sp. EM595, Pantoea sp. P10QLC, Pantoea sp. P8SAA, strain EM595
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