STRINGSTRING
accD accD accA accA ALS21025.1 ALS21025.1 ALS21096.1 ALS21096.1 ALS21160.1 ALS21160.1 leuC leuC leuD leuD ackA ackA ALS21523.1 ALS21523.1 ALS21717.1 ALS21717.1 ALS21718.1 ALS21718.1 ALS21719.1 ALS21719.1 ALS21770.1 ALS21770.1 ALS21790.1 ALS21790.1 ALS21873.1 ALS21873.1 ALS21885.1 ALS21885.1 ALS21927.1 ALS21927.1 ALS22033.1 ALS22033.1 ALS22034.1 ALS22034.1 ALS22061.1 ALS22061.1 ALS22593.1 ALS22593.1 ALS22600.1 ALS22600.1 ALS22794.1 ALS22794.1 ALS22795.1 ALS22795.1 ALS22814.1 ALS22814.1 ALS22915.1 ALS22915.1 ALS22941.1 ALS22941.1 ilvE ilvE ilvD ilvD ALS23573.1 ALS23573.1 leuB leuB leuA leuA ilvC ilvC ALS24071.1 ALS24071.1 ALS24072.1 ALS24072.1 ALS24184.1 ALS24184.1 ALS24287.1 ALS24287.1 ALS24304.1 ALS24304.1 ALS25278.1 ALS25278.1 ALS25402.1 ALS25402.1 ALS25407.1 ALS25407.1 ALS25426.1 ALS25426.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
accDSubunit beta of acetyl-CoA carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (308 aa)
accAacetyl-CoA carboxyltransferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (326 aa)
ALS21025.1Citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (540 aa)
ALS21096.1Branched-chain amino acid aminotransferase. (279 aa)
ALS21160.1Acetolactate synthase; Belongs to the TPP enzyme family. (583 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)
ALS21523.1acetyl-CoA synthetase. (574 aa)
ALS21717.1Subunit alpha of 2-oxoglutarate ferredoxin oxidoreductase. (583 aa)
ALS21718.12-oxoacid ferredoxin oxidoreductase. (288 aa)
ALS21719.1Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (189 aa)
ALS21770.1Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (715 aa)
ALS21790.13-isopropylmalate dehydrogenase. (366 aa)
ALS21873.1Lactate 2-monooxygenase. (383 aa)
ALS21885.12-hydroxy-3-oxopropionate reductase. (290 aa)
ALS21927.1Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (568 aa)
ALS22033.1Pyruvate synthase. (767 aa)
ALS22034.1Ferredoxin. (334 aa)
ALS22061.13-isopropylmalate dehydrogenase. (352 aa)
ALS22593.1Acetate CoA-transferase YdiF; Belongs to the 3-oxoacid CoA-transferase family. (531 aa)
ALS22600.1Acetate CoA-transferase YdiF; Belongs to the 3-oxoacid CoA-transferase family. (546 aa)
ALS22794.1Biotin carboxylase subunit of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa)
ALS22795.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa)
ALS22814.1Acetolactate synthase; Belongs to the TPP enzyme family. (557 aa)
ALS22915.1Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (897 aa)
ALS22941.1Acetate CoA-transferase YdiF; Belongs to the 3-oxoacid CoA-transferase family. (520 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (292 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (562 aa)
ALS23573.1Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (560 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (359 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
ALS24071.1Acetolactate synthase. (162 aa)
ALS24072.1Catalytic subunit of acetolactate synthase. (579 aa)
ALS24184.12-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Belongs to the alpha-IPM synthase/homocitrate synthase family. (531 aa)
ALS24287.1Quinone oxidoreductase. (337 aa)
ALS24304.1succinyl-CoA:coenzyme A transferase. (504 aa)
ALS25278.1Thiamine pyrophosphate domain-containing TPP-binding protein; Belongs to the TPP enzyme family. (546 aa)
ALS25402.1Catalytic subunit of acetolactate synthase; Belongs to the TPP enzyme family. (603 aa)
ALS25407.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (495 aa)
ALS25426.1acetyl-CoA synthetase. (575 aa)
Your Current Organism:
Paenibacillus naphthalenovorans
NCBI taxonomy Id: 162209
Other names: ATCC BAA-206, DSM 14203, P. naphthalenovorans, Paenibacillus naphthalenovorans Daane et al. 2002, Paenibacillus sp. PR-N1, Paenibacillus sp. PR-N16, Paenibacillus sp. PR-N5, Paenibacillus sp. PS-N1, Paenibacillus sp. PS-N6, Paenibacillus sp. SA-N1, strain PR-N1
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