STRINGSTRING
murE murE ALS20486.1 ALS20486.1 ddl ddl ALS20673.1 ALS20673.1 ALS20723.1 ALS20723.1 uppP uppP ALS20944.1 ALS20944.1 murI murI ALS21212.1 ALS21212.1 mraY mraY murD murD murG murG murB murB murA murA ALS21469.1 ALS21469.1 ALS21601.1 ALS21601.1 ALS21664.1 ALS21664.1 ALS21698.1 ALS21698.1 ALS21848.1 ALS21848.1 ALS21882.1 ALS21882.1 uppP-2 uppP-2 ALS25266.1 ALS25266.1 ALS25162.1 ALS25162.1 ALS25109.1 ALS25109.1 ALS25045.1 ALS25045.1 glmU glmU murA-4 murA-4 ALS24746.1 ALS24746.1 ALS24695.1 ALS24695.1 ALS24578.1 ALS24578.1 ALS24564.1 ALS24564.1 ALS24535.1 ALS24535.1 murA-3 murA-3 ALS24499.1 ALS24499.1 ALS24498.1 ALS24498.1 ALS24364.1 ALS24364.1 ALS24353.1 ALS24353.1 ALS24291.1 ALS24291.1 ALS24196.1 ALS24196.1 ALS24159.1 ALS24159.1 ALS24078.1 ALS24078.1 ALS23623.1 ALS23623.1 amj amj murC murC mltG mltG ALS23149.1 ALS23149.1 murA-2 murA-2 ALS22909.1 ALS22909.1 ALS22775.1 ALS22775.1 ALS22752.1 ALS22752.1 ALS22731.1 ALS22731.1 ALS22690.1 ALS22690.1 ALS21886.1 ALS21886.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (504 aa)
ALS20486.1Mur ligase. (526 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (392 aa)
ALS20673.1Cell division protein FtsI. (684 aa)
ALS20723.1UDP-glucose 6-dehydrogenase. (445 aa)
uppPUDP pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa)
ALS20944.1Transcriptional regulator. (366 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (269 aa)
ALS21212.1Histidine kinase. (535 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (320 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (472 aa)
murGUDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (357 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (301 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (422 aa)
ALS21469.1Cell wall hydrolase. (142 aa)
ALS21601.1KH domain-containing; Belongs to the UPF0109 family. (76 aa)
ALS21664.1Hypothetical protein. (164 aa)
ALS21698.1Hydrolase. (270 aa)
ALS21848.1Spore cortex-lytic protein. (216 aa)
ALS21882.1Spore cortex-lytic protein. (214 aa)
uppP-2UDP pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (265 aa)
ALS25266.1Putative L,D-transpeptidase YkuD. (111 aa)
ALS25162.1Glycosidase. (349 aa)
ALS25109.1Zinc-binding alcohol dehydrogenase. (365 aa)
ALS25045.1Histidine kinase. (1027 aa)
glmUN-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (465 aa)
murA-4UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
ALS24746.1Carboxypeptidase. (690 aa)
ALS24695.1Membrane protein. (499 aa)
ALS24578.1DNA-binding protein. (206 aa)
ALS24564.1Peptidase M15; Belongs to the peptidase S11 family. (428 aa)
ALS24535.1UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (380 aa)
murA-3UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (442 aa)
ALS24499.1N-acetylmannosaminyltransferase; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. (247 aa)
ALS24498.1UDP-phosphate N-acetylglucosaminyl 1-phosphate transferase. (386 aa)
ALS24364.1Transcriptional regulator. (500 aa)
ALS24353.1Histidine kinase. (563 aa)
ALS24291.1Histidine kinase. (579 aa)
ALS24196.1Transcriptional regulator. (345 aa)
ALS24159.1UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (359 aa)
ALS24078.1Phosphatidic acid phosphatase. (176 aa)
ALS23623.1Peptidase M23. (354 aa)
amjMembrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (263 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (445 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (352 aa)
ALS23149.1Penicillin-binding protein. (601 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (431 aa)
ALS22909.1UDP-phosphate N-acetylgalactosaminyl-1-phosphate transferase. (311 aa)
ALS22775.1Hypothetical protein. (286 aa)
ALS22752.1D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (413 aa)
ALS22731.1Peptidase M15; Belongs to the peptidase S11 family. (411 aa)
ALS22690.1Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)
ALS21886.1Histidine kinase. (596 aa)
Your Current Organism:
Paenibacillus naphthalenovorans
NCBI taxonomy Id: 162209
Other names: ATCC BAA-206, DSM 14203, P. naphthalenovorans, Paenibacillus naphthalenovorans Daane et al. 2002, Paenibacillus sp. PR-N1, Paenibacillus sp. PR-N16, Paenibacillus sp. PR-N5, Paenibacillus sp. PS-N1, Paenibacillus sp. PS-N6, Paenibacillus sp. SA-N1, strain PR-N1
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