STRINGSTRING
OMJ33866.1 OMJ33866.1 OMJ33927.1 OMJ33927.1 OMJ33976.1 OMJ33976.1 OMJ33846.1 OMJ33846.1 OMJ33754.1 OMJ33754.1 OMJ33755.1 OMJ33755.1 purD purD purK purK purE purE OMJ33613.1 OMJ33613.1 nrdR nrdR OMJ33457.1 OMJ33457.1 OMJ33535.1 OMJ33535.1 rph rph OMJ33545.1 OMJ33545.1 gmk gmk OMJ33346.1 OMJ33346.1 OMJ33389.1 OMJ33389.1 OMJ33185.1 OMJ33185.1 OMJ33196.1 OMJ33196.1 OMJ33251.1 OMJ33251.1 OMJ33252.1 OMJ33252.1 OMJ33035.1 OMJ33035.1 purL purL OMJ32948.1 OMJ32948.1 OMJ32831.1 OMJ32831.1 OMJ32851.1 OMJ32851.1 OMJ32713.1 OMJ32713.1 OMJ32726.1 OMJ32726.1 OMJ32727.1 OMJ32727.1 OMJ32728.1 OMJ32728.1 purH purH OMJ32592.1 OMJ32592.1 OMJ32491.1 OMJ32491.1 OMJ32499.1 OMJ32499.1 OMJ32363.1 OMJ32363.1 OMJ32272.1 OMJ32272.1 purA purA adk adk BSZ14_09330 BSZ14_09330 OMJ32238.1 OMJ32238.1 purM purM purN purN ndk ndk guaB guaB OMJ32105.1 OMJ32105.1 OMJ32124.1 OMJ32124.1 OMJ32058.1 OMJ32058.1 ihfA ihfA OMJ31934.1 OMJ31934.1 OMJ31959.1 OMJ31959.1 cysN cysN cysD cysD OMJ31776.1 OMJ31776.1 purF purF OMJ31587.1 OMJ31587.1 OMJ31575.1 OMJ31575.1 OMJ31494.1 OMJ31494.1 tilS tilS OMJ31398.1 OMJ31398.1 OMJ31426.1 OMJ31426.1 OMJ31374.1 OMJ31374.1 OMJ31307.1 OMJ31307.1 prs prs OMJ31282.1 OMJ31282.1 apt apt ychF ychF OMJ31229.1 OMJ31229.1 OMJ31164.1 OMJ31164.1 OMJ31140.1 OMJ31140.1 OMJ31076.1 OMJ31076.1 OMJ31079.1 OMJ31079.1 guaA guaA purQ purQ purS purS purC purC truA truA OMJ30779.1 OMJ30779.1 OMJ30750.1 OMJ30750.1 OMJ30667.1 OMJ30667.1 surE surE OMJ30525.1 OMJ30525.1 tadA tadA BSZ14_18775 BSZ14_18775 OMJ30456.1 OMJ30456.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OMJ33866.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
OMJ33927.1AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
OMJ33976.1Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
OMJ33846.1Aldehyde dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
OMJ33754.1Molybdopterin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
OMJ33755.1Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (736 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (425 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (351 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (159 aa)
OMJ33613.1BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (94 aa)
nrdRTranscriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (155 aa)
OMJ33457.1AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
OMJ33535.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (438 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
OMJ33545.1Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (208 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (201 aa)
OMJ33346.1Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
OMJ33389.1Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
OMJ33185.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
OMJ33196.1DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
OMJ33251.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
OMJ33252.1Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
OMJ33035.1tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (741 aa)
OMJ32948.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
OMJ32831.1AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
OMJ32851.1Bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (699 aa)
OMJ32713.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (488 aa)
OMJ32726.1Aldehyde dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
OMJ32727.1Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
OMJ32728.1Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (745 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa)
OMJ32592.1Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family. (193 aa)
OMJ32491.1Polysaccharide deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
OMJ32499.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
OMJ32363.1Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
OMJ32272.1Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family. (295 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa)
BSZ14_09330Multidrug transporter AcrB; Frameshifted; incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
OMJ32238.1Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (197 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
OMJ32105.1AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
OMJ32124.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
OMJ32058.1Magnesium transporter; Acts as a magnesium transporter. (452 aa)
ihfAIntegration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (99 aa)
OMJ31934.1alpha-D-glucose phosphate-specific phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (541 aa)
OMJ31959.1Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
cysNAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (637 aa)
cysDSulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
OMJ31776.1Histidine triad nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (499 aa)
OMJ31587.1Transthyretin family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (46 aa)
OMJ31575.1Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
OMJ31494.1Polysaccharide deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
tilStRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (330 aa)
OMJ31398.1AMP nucleosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
OMJ31426.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (193 aa)
OMJ31374.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
OMJ31307.1Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
prsPhosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa)
OMJ31282.1Magnesium transporter; Acts as a magnesium transporter. (470 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (178 aa)
ychFRedox-regulated ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
OMJ31229.1NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
OMJ31164.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (640 aa)
OMJ31140.1Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (351 aa)
OMJ31076.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
OMJ31079.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (517 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (222 aa)
purSPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (76 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (259 aa)
truAtRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (249 aa)
OMJ30779.1Integration host factor subunit beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (95 aa)
OMJ30750.1BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (78 aa)
OMJ30667.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (254 aa)
OMJ30525.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (142 aa)
BSZ14_18775IS256 family transposase; Frameshifted; incomplete; partial in the middle of a contig; missing start and stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
OMJ30456.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa)
Your Current Organism:
Sphingomonas sp. Sph1
NCBI taxonomy Id: 1628084
Other names: S. sp. Sph1(2015), Sphingomonas sp. Sph1(2015)
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