STRINGSTRING
CL1_0205 CL1_0205 CL1_0451 CL1_0451 CL1_0496 CL1_0496 CL1_0542 CL1_0542 purQ purQ purF purF CL1_0800 CL1_0800 CL1_0909 CL1_0909 CL1_1122 CL1_1122 CL1_1144 CL1_1144 pyrI pyrI pyrB pyrB CL1_1333 CL1_1333 CL1_1359 CL1_1359 CL1_1439 CL1_1439 CL1_1601 CL1_1601 CL1_1777 CL1_1777 purA purA CL1_1883 CL1_1883 glmS glmS CL1_2035 CL1_2035
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CL1_02054-aminobutyrate aminotransferase 1; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (447 aa)
CL1_0451Putative aminotransferase 2; COG0436. (398 aa)
CL1_0496Putative aminotransferase 3; COG0436. (544 aa)
CL1_0542Glutamate dehydrogenase; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)
purQPhosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interac [...] (223 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (444 aa)
CL1_0800L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (465 aa)
CL1_0909Glutamine synthetase; COG0174; Belongs to the glutamine synthetase family. (440 aa)
CL1_11224-aminobutyrate aminotransferase 2; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
CL1_1144Putative glutamate synthase subunit beta; COG0493. (351 aa)
pyrIAspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (151 aa)
pyrBAspartate carbamoyltransferase catalytic subunit; COG0540. (311 aa)
CL1_1333L-asparaginase; COG1446. (306 aa)
CL1_1359Glutamate synthase small subunit-like protein; COG0493. (477 aa)
CL1_1439Putative oxidoreductase; COG0493. (480 aa)
CL1_1601Asparagine synthase; COG0367. (480 aa)
CL1_1777Adenylosuccinate lyase; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (451 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (339 aa)
CL1_1883Putative aspartate racemase 1; COG1794. (226 aa)
glmSGlucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa)
CL1_2035Putative aspartate racemase 2; COG1794. (235 aa)
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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