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kdgK_1 kdgK_1 AMV22831.1 AMV22831.1 AMV22856.1 AMV22856.1 gndA_1 gndA_1 tkt tkt nagC nagC pgl_1 pgl_1 mro mro glcK_1 glcK_1 pyk pyk rpe rpe ppdK ppdK tal_1 tal_1 pfkA1 pfkA1 rbsK rbsK nudF nudF lldD lldD gmuE gmuE glcK_2 glcK_2 pgk pgk gap1 gap1 deoC2 deoC2 zwf_1 zwf_1 gndA_2 gndA_2 pgcA pgcA cfiB cfiB galM galM tal_2 tal_2 pspB_1 pspB_1 eno eno aceF aceF aceE aceE garD garD AMV27373.1 AMV27373.1 zwf_2 zwf_2 pgm_2 pgm_2 ldh_2 ldh_2 xpkA xpkA serA_1 serA_1 rpiA rpiA prs prs serA_2 serA_2 yihX yihX kdgK_2 kdgK_2 kdgA kdgA pgi_1 pgi_1 AMV28574.1 AMV28574.1 pckG pckG serA_3 serA_3 pgl_2 pgl_2 pgk/tpi pgk/tpi ywlF ywlF gno gno pgi_2 pgi_2 korA korA korB korB gntK gntK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kdgK_12-dehydro-3-deoxygluconokinase. (361 aa)
AMV22831.1Cofactor-independent phosphoglycerate mutase. (404 aa)
AMV22856.1Hypothetical protein. (277 aa)
gndA_16-phosphogluconate dehydrogenase, NADP(+)-dependent, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (490 aa)
tktTransketolase; Belongs to the transketolase family. (683 aa)
nagCN-acetylglucosamine repressor. (388 aa)
pgl_16-phosphogluconolactonase. (400 aa)
mroAldose 1-epimerase precursor; Converts alpha-aldose to the beta-anomer. (386 aa)
glcK_1Glucokinase. (331 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (479 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (222 aa)
ppdKPyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (893 aa)
tal_1Transaldolase. (234 aa)
pfkA16-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (428 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (307 aa)
nudFADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (174 aa)
lldDL-lactate dehydrogenase. (391 aa)
gmuEPutative fructokinase. (318 aa)
glcK_2Glucokinase. (335 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa)
gap1Glyceraldehyde-3-phosphate dehydrogenase 1; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (349 aa)
deoC2Deoxyribose-phosphate aldolase 2; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (228 aa)
zwf_1Glucose-6-phosphate 1-dehydrogenase. (150 aa)
gndA_26-phosphogluconate dehydrogenase, NADP(+)-dependent, decarboxylating. (339 aa)
pgcAPhosphoglucomutase. (656 aa)
cfiB2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1157 aa)
galMAldose 1-epimerase. (344 aa)
tal_2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (363 aa)
pspB_1Putative phosphoserine phosphatase 2. (238 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa)
aceFDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. (545 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (923 aa)
garDD-galactarate dehydratase. (522 aa)
AMV27373.1Hypothetical protein. (157 aa)
zwf_2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (480 aa)
pgm_2Phosphoglucomutase. (548 aa)
ldh_2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (319 aa)
xpkAXylulose-5-phosphate phosphoketolase. (817 aa)
serA_1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa)
rpiARibose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (230 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (332 aa)
serA_2D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (539 aa)
yihXAlpha-D-glucose-1-phosphate phosphatase YihX. (205 aa)
kdgK_22-dehydro-3-deoxygluconokinase. (327 aa)
kdgAKHG/KDPG aldolase. (216 aa)
pgi_1Glucose-6-phosphate isomerase. (501 aa)
AMV28574.1Cofactor-independent phosphoglycerate mutase. (401 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
serA_3D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
pgl_26-phosphogluconolactonase. (370 aa)
pgk/tpiBifunctional PGK/TIM; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa)
ywlFPutative sugar phosphate isomerase YwlF. (155 aa)
gnoGluconate 5-dehydrogenase. (259 aa)
pgi_2Glucose-6-phosphate isomerase; Belongs to the GPI family. (544 aa)
korA2-oxoglutarate oxidoreductase subunit KorA. (658 aa)
korB2-oxoglutarate oxidoreductase subunit KorB. (344 aa)
gntKThermoresistant gluconokinase. (162 aa)
Your Current Organism:
Gemmata sp. SHPL17
NCBI taxonomy Id: 1630693
Other names: G. sp. SH-PL17, Gemmata sp. SH-PL17
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