(10 nodes) Single hybrid motif network (Gemmata sp. SHPL17)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	aceF	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. (545 aa)
	AMV27213.1	Branched-chain alpha-keto acid dehydrogenase subunit E2. (80 aa)
	accB	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (177 aa)
	gcvH_2	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (137 aa)
	sucB	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (406 aa)
	odhB	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex. (403 aa)
	bkdB	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (443 aa)
	AMV25266.1	Hypothetical protein. (343 aa)
	cfiB	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1157 aa)
	gcvH_1	Glycine cleavage system H protein. (170 aa)

Your Current Organism:

Gemmata sp. SHPL17

NCBI taxonomy Id: 1630693
Other names: G. sp. SH-PL17, Gemmata sp. SH-PL17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMV27213.1	gcvH_1	VT84_22620	VT84_20560	Branched-chain alpha-keto acid dehydrogenase subunit E2.	Glycine cleavage system H protein.	0.490
AMV27213.1	gcvH_2	VT84_22620	VT84_25725	Branched-chain alpha-keto acid dehydrogenase subunit E2.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.490
accB	aceF	VT84_38860	VT84_22340	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.912
accB	odhB	VT84_38860	VT84_03180	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex.	0.912
aceF	accB	VT84_22340	VT84_38860	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.912
aceF	cfiB	VT84_22340	VT84_19040	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.829
aceF	gcvH_1	VT84_22340	VT84_20560	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	Glycine cleavage system H protein.	0.490
aceF	gcvH_2	VT84_22340	VT84_25725	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.490
aceF	odhB	VT84_22340	VT84_03180	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex.	0.923
bkdB	gcvH_1	VT84_03810	VT84_20560	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.	Glycine cleavage system H protein.	0.490
bkdB	gcvH_2	VT84_03810	VT84_25725	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.490
cfiB	aceF	VT84_19040	VT84_22340	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.829
cfiB	odhB	VT84_19040	VT84_03180	2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex.	0.829
gcvH_1	AMV27213.1	VT84_20560	VT84_22620	Glycine cleavage system H protein.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.490
gcvH_1	aceF	VT84_20560	VT84_22340	Glycine cleavage system H protein.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.490
gcvH_1	bkdB	VT84_20560	VT84_03810	Glycine cleavage system H protein.	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.	0.490
gcvH_1	gcvH_2	VT84_20560	VT84_25725	Glycine cleavage system H protein.	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	0.921
gcvH_1	odhB	VT84_20560	VT84_03180	Glycine cleavage system H protein.	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex.	0.490
gcvH_1	sucB	VT84_20560	VT84_00925	Glycine cleavage system H protein.	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.490
gcvH_2	AMV27213.1	VT84_25725	VT84_22620	Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.490