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AMV22831.1 AMV22831.1 fae_1 fae_1 mtdA mtdA fhcD_1 fhcD_1 AMV23890.1 AMV23890.1 pfkA1 pfkA1 AMV24387.1 AMV24387.1 nqo1_1 nqo1_1 ackA ackA mch mch ttuD ttuD mdh mdh fdnH fdnH fdnG_1 fdnG_1 fdhA fdhA xylB_1 xylB_1 fhcD_2 fhcD_2 pucG pucG AMV25954.1 AMV25954.1 pspB_1 pspB_1 fhcC fhcC eno eno fae_2 fae_2 acsA acsA serA_1 serA_1 serA_2 serA_2 fhcA fhcA glyA glyA AMV28415.1 AMV28415.1 AMV28574.1 AMV28574.1 serA_3 serA_3 AMV29045.1 AMV29045.1 AMV29046.1 AMV29046.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMV22831.1Cofactor-independent phosphoglycerate mutase. (404 aa)
fae_1Formaldehyde-activating enzyme. (165 aa)
mtdABifunctional protein MdtA. (291 aa)
fhcD_1Formyltransferase/hydrolase complex subunit D. (316 aa)
AMV23890.1Hypothetical protein. (482 aa)
pfkA16-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (428 aa)
AMV24387.1Hypothetical protein. (237 aa)
nqo1_1NADH-quinone oxidoreductase subunit 1. (682 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (365 aa)
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family. (315 aa)
ttuDPutative hydroxypyruvate reductase. (432 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
fdnHFormate dehydrogenase, nitrate-inducible, iron-sulfur subunit. (322 aa)
fdnG_1Formate dehydrogenase, nitrate-inducible, major subunit precursor; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (904 aa)
fdhAFormate dehydrogenase subunit alpha precursor. (173 aa)
xylB_1Aryl-alcohol dehydrogenase. (346 aa)
fhcD_2Formyltransferase/hydrolase complex subunit D; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family. (299 aa)
pucGPurine catabolism protein PucG. (392 aa)
AMV25954.1Carbamoyl phosphate synthase-like protein. (323 aa)
pspB_1Putative phosphoserine phosphatase 2. (238 aa)
fhcCFormyltransferase/hydrolase complex Fhc subunit C. (269 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa)
fae_2Formaldehyde-activating enzyme. (149 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa)
serA_1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa)
serA_2D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (539 aa)
fhcAFormyltransferase/hydrolase complex Fhc subunit A. (552 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
AMV28415.1Hypothetical protein; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. (160 aa)
AMV28574.1Cofactor-independent phosphoglycerate mutase. (401 aa)
serA_3D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
AMV29045.1Hydantoinase/oxoprolinase. (370 aa)
AMV29046.1Hypothetical protein. (204 aa)
Your Current Organism:
Gemmata sp. SHPL17
NCBI taxonomy Id: 1630693
Other names: G. sp. SH-PL17, Gemmata sp. SH-PL17
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