STRINGSTRING
glyA glyA fumC fumC lysC lysC AMV30695.1 AMV30695.1 AMV30696.1 AMV30696.1 atzA atzA AMV30698.1 AMV30698.1 AMV30699.1 AMV30699.1 AMV30700.1 AMV30700.1 AMV30701.1 AMV30701.1 aroH_1 aroH_1 dapF dapF AMV31207.1 AMV31207.1 AMV31208.1 AMV31208.1 dapA_1 dapA_1 dapB dapB astB astB dapA_2 dapA_2 astA astA ppc ppc argE_1 argE_1 argE_2 argE_2 aroA aroA AMV32763.1 AMV32763.1 gltB_2 gltB_2 AMV33170.1 AMV33170.1 AMV33403.1 AMV33403.1 AMV33544.1 AMV33544.1 aroB_1 aroB_1 aroB_2 aroB_2 asd asd dapA_3 dapA_3 aroL aroL folK folK dapA_4 dapA_4 nadA nadA cpg2 cpg2 aroC aroC folP folP AMV34753.1 AMV34753.1 AMV34797.1 AMV34797.1 pheA pheA yxeP yxeP lysA lysA AMV35571.1 AMV35571.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (505 aa)
lysCAspartokinase. (592 aa)
AMV30695.1Dihydroorotase. (928 aa)
AMV30696.1Hypothetical protein. (437 aa)
atzAAtrazine chlorohydrolase. (445 aa)
AMV30698.1Imidazolonepropionase. (905 aa)
AMV30699.1Hypothetical protein. (432 aa)
AMV30700.1Imidazolonepropionase. (437 aa)
AMV30701.1Imidazolonepropionase. (527 aa)
aroH_1Chorismate mutase AroH. (149 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (287 aa)
AMV31207.1Imidazolonepropionase. (1084 aa)
AMV31208.1Hypothetical protein. (442 aa)
dapA_14-hydroxy-tetrahydrodipicolinate synthase. (333 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (266 aa)
astBN-succinylarginine dihydrolase. (449 aa)
dapA_24-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (314 aa)
astAArginine N-succinyltransferase. (344 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (927 aa)
argE_1Acetylornithine deacetylase. (383 aa)
argE_2Acetylornithine deacetylase. (400 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (439 aa)
AMV32763.1Shikimate 5-dehydrogenase. (289 aa)
gltB_2Ferredoxin-dependent glutamate synthase 1. (1519 aa)
AMV33170.1Imidazolonepropionase. (463 aa)
AMV33403.1Hypothetical protein. (312 aa)
AMV33544.15-dehydro-4-deoxyglucarate dehydratase. (303 aa)
aroB_13-dehydroquinate synthase. (400 aa)
aroB_23-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
asdAspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (375 aa)
dapA_34-hydroxy-tetrahydrodipicolinate synthase; Belongs to the DapA family. (307 aa)
aroLShikimate kinase 2. (142 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (284 aa)
dapA_44-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa)
nadAQuinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (376 aa)
cpg2Carboxypeptidase G2 precursor. (410 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (382 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (284 aa)
AMV34753.1GXGXG motif protein. (216 aa)
AMV34797.1Hypothetical protein. (357 aa)
pheAPrephenate dehydratase. (353 aa)
yxePPutative hydrolase YxeP. (490 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (424 aa)
AMV35571.1Pterin binding enzyme. (472 aa)
Your Current Organism:
Pirellula sp. SHSr6A
NCBI taxonomy Id: 1632865
Other names: P. sp. SH-Sr6A, Pirellula sp. SH-Sr6A
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.