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apgM apgM pfkA1 pfkA1 rpe rpe ppdK ppdK PSM36_0474 PSM36_0474 pgk pgk nifJ nifJ pyk pyk PSM36_0621 PSM36_0621 serC serC fbaB fbaB sucD sucD sucC sucC PSM36_0697 PSM36_0697 PSM36_0706 PSM36_0706 PSM36_0711 PSM36_0711 vorB vorB vorA vorA PSM36_0715 PSM36_0715 PSM36_0887 PSM36_0887 icd icd PSM36_0889 PSM36_0889 PSM36_0890 PSM36_0890 PSM36_0958 PSM36_0958 gcvT gcvT folD folD pdhA pdhA pdhB pdhB PSM36_1042 PSM36_1042 PSM36_1043 PSM36_1043 PSM36_1073 PSM36_1073 PSM36_1170 PSM36_1170 PSM36_1171 PSM36_1171 PSM36_1267 PSM36_1267 fhs fhs PSM36_1295 PSM36_1295 PSM36_1308 PSM36_1308 mutB mutB PSM36_1318 PSM36_1318 PSM36_1434 PSM36_1434 PSM36_1521 PSM36_1521 PSM36_1818 PSM36_1818 PSM36_1820 PSM36_1820 prs prs gcvP gcvP fba fba PSM36_1936 PSM36_1936 gcvH gcvH PSM36_2015 PSM36_2015 PSM36_2049 PSM36_2049 pfkA3 pfkA3 PSM36_2140 PSM36_2140 tal tal PSM36_2183 PSM36_2183 korA korA korB korB maeB maeB tpiA tpiA acn acn PSM36_2445 PSM36_2445 acoC acoC PSM36_2447 PSM36_2447 acoA acoA mdh mdh glyA glyA pta pta PSM36_2749 PSM36_2749 ackA ackA zwf zwf pgl pgl katA katA eno eno PSM36_2950 PSM36_2950 PSM36_2994 PSM36_2994 odhA odhA pgi pgi acsA acsA fumA fumA fumC fumC PSM36_3199 PSM36_3199 PSM36_3246 PSM36_3246 sdhA sdhA PSM36_3248 PSM36_3248 gpmA gpmA pckA pckA gnd gnd PSM36_3418 PSM36_3418 PSM36_3439 PSM36_3439 PSM36_3440 PSM36_3440 PSM36_3467 PSM36_3467
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query proteins and first shell of interactors
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proteins of unknown 3D structure
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apgMThis family represents 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (iPGAM), it is a metalloenzyme found particularly in archaea and some eubacteria. It is responsble for the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; High confidence in function and specificity. (401 aa)
pfkA16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (338 aa)
rpeRibulose-phosphate 3-epimerase; D-ribulose 5-phosphate = D-xylulose 5-phosphate; High confidence in function and specificity; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa)
ppdKPyruvate, phosphate dikinase; ATP + pyruvate + phosphate <=> AMP + phosphoenolpyruvate + diphosphate; High confidence in function and specificity; Belongs to the PEP-utilizing enzyme family. (906 aa)
PSM36_0474Putative D-isomer specific 2-hydroxyacid dehydrogenases; 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrange [...] (298 aa)
pgkPhosphoglycerate kinase; ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate; High confidence in function and specificity; Belongs to the phosphoglycerate kinase family. (419 aa)
nifJPyruvate dehydrogenase (NADP(+)); Pyruvate + CoA + NADP(+) <=> acetyl-CoA + CO(2) + NADPH; High confidence in function and specificity. (1194 aa)
pykATP + pyruvate = ADP + phosphoenolpyruvate; High confidence in function and specificity; Belongs to the pyruvate kinase family. (490 aa)
PSM36_0621Putative D-3-Phosphoglycerate Dehydrogenases; Phosphoglycerate dehydrogenases (PGDHs) catalyze the initial step in the biosynthesis of L-serine from D-3-phosphoglycerate. PGDHs come in 3 distinct structural forms, with this first group being related to 2-hydroxy acid dehydrogenases, sharing structural similarity to formate and glycerate dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily, which also include groups such as L-alanine dehydrogenase and S-adenosylhomocysteine hydrolase; High confidence in function and specificity. (309 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (359 aa)
fbaBFructose-bisphosphate aldolase class 1; D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate; High confidence in function and specificity. (352 aa)
sucDSuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (288 aa)
sucCSuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (376 aa)
PSM36_0697Phosphoserine phosphatase; The ACT_PSP_2 CD includes the second of the two ACT domains found N-terminal of phosphoserine phosphatase (PSP, SerB). PSPs belong to the L-2-haloacid dehalogenase-like protein superfamily. PSP is involved in serine metabolism; serine is synthesized from phosphoglycerate through sequential reactions catalyzed by 3-phosphoglycerate dehydrogenase (SerA), 3-phosphoserine aminotransferase (SerC), and SerB. Members of this CD belong to the superfamily of ACT regulatory domains, Links, ?; High confidence in function and specificity. (410 aa)
PSM36_0706The enzyme activities methylenetetrahydrofolate reductase and 5,10-methylenetetrahydrofolate reductase (FADH) differ in that 1.5.1.20 (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while 1.7.99.5 (assigned in many bacteria) is flexible with respect to the acceptor; both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as 1.5.1.20 and 1.7.99.5, this model describes the subset of proteins found in bacteria, and currently designated 1.7.99.5. This protein is an FAD-containing flavoprotein. [Amino acid biosynt [...] (316 aa)
PSM36_07112-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Hypothetical protein. (76 aa)
vorBKetoisovalerate oxidoreductase subunit VorB; 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin <=> S-(2-methylpropanoyl)-CoA + CO(2) + 2 reduced ferredoxin + H(+); High confidence in function and specificity. (360 aa)
vorAKetoisovalerate oxidoreductase subunit VorA; 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+; High confidence in function and specificity. (253 aa)
PSM36_0715This family includes a region of the large protein pyruvate-flavodoxin oxidoreductase and the whole pyruvate ferredoxin oxidoreductase gamma subunit protein. It is not known whether the gamma subunit has a catalytic or regulatory role. Pyruvate oxidoreductase (POR) catalyses the final step in the fermentation of carbohydrates in anaerobic microorganisms. This involves the oxidative decarboxylation of pyruvate with the participation of thiamine followed by the transfer of an acetyl moiety to coenzyme A for the synthesis of acetyl-CoA. The family also includes pyruvate flavodoxin oxidore [...] (184 aa)
PSM36_0887Aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate; High confidence in function and specificity. (750 aa)
icdIsocitrate dehydrogenase [NADP]; Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH; High confidence in function and specificity. (419 aa)
PSM36_0889Citrate synthaseis a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle, namely the conversion of oxaloacetate and acetyl-coenzyme A into citrate and coenzyme A. This reaction is important for energy generation and for carbon assimilation; High confidence in function and specificity. (451 aa)
PSM36_0890Isocitrate dehydrogenase [NADP], chloroplastic; Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH; High confidence in function and specificity; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
PSM36_0958Pyruvate carboxylase subunit B; High confidence in function and specificity. (639 aa)
gcvTGlycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (361 aa)
folDBifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (304 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (369 aa)
pdhBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3); High confidence in function and specificity. (325 aa)
PSM36_1042Branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; High confidence in function and specificity. (442 aa)
PSM36_1043Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]; High confidence in function and specificity. (277 aa)
PSM36_1073Glycerate-2-kinase; High confidence in function and specificity. (450 aa)
PSM36_1170Transketolase; This model is designed to capture orthologs of bacterial transketolases. The group includes two from the yeast Saccharomyces cerevisiae but excludes dihydroxyactetone synthases (formaldehyde transketolases) from various yeasts and the even more distant mammalian transketolases. Among the family of thiamine diphosphate-dependent enzymes that includes transketolases, dihydroxyacetone synthases, pyruvate dehydrogenase E1-beta subunits, and deoxyxylulose-5-phosphate synthases, mammalian and bacterial transketolases seem not to be orthologous. [Energy metabolism, Pentose phos [...] (675 aa)
PSM36_1171Ribose-5-phosphate isomerase B; D-ribose 5-phosphate <=> D-ribulose 5-phosphate; High confidence in function and specificity. (151 aa)
PSM36_1267L-serine dehydratase, iron-sulfur-dependent, single chain form; This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme re [...] (404 aa)
fhsFormate-tetrahydrofolate ligase; ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate; High confidence in function and specificity; Belongs to the formate--tetrahydrofolate ligase family. (554 aa)
PSM36_1295This model models one branch of the ROK superfamily of proteins. The three members of the seed alignment for this model all have experimental evidence for activity as glucokinase, but the set of related proteins is crowded with paralogs of different or unknown function. Proteins scoring above the trusted_cutoff will show strong similarity to at least one known glucokinase and may be designated as putative glucokinases. However, definitive identification of glucokinases should be done only with extreme caution. [Unknown function, General]; High confidence in function and specificity. (321 aa)
PSM36_1308methylmalonyl-CoA mutase; The adenosylcobalamin-binding, catalytic chain of methylmalonyl-CoA mutase may form homodimers, as in mitochondrion and E. coli, or heterodimers with a shorter, homologous chain that does not bind adenosylcobalamin. This model describes this non-catalytic beta chain, as found in the enzyme from Propionibacterium freudenreichii, for which the 3-dimensional structure has been solved. [Central intermediary metabolism, Other]; High confidence in function and specificity. (632 aa)
mutBMethylmalonyl-CoA mutase large subunit; Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates; High confidence in function and specificity. (715 aa)
PSM36_1318Medium-chain acyl-CoA synthetase (MACS) of AAE_MA like; MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. This family of MACS enzymes is found in archaea and bacteria. It is represented by the acyl-adenylating enzyme from Methanosarcina acetivorans (AAE_MA). AAE_MA is most active with propionate, butyrate, and the branched analogs: 2-methyl-propionate, butyrate, and pentanoate. The specific activity [...] (554 aa)
PSM36_1434Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second; High confidence in function and specificity. (647 aa)
PSM36_1521Glyceraldehyde-3-phosphate dehydrogenase, cytosolic; D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
PSM36_1818Propionyl-CoA carboxylase beta chain, mitochondrial; ATP + propanoyl-CoA + HCO3-= ADP + phosphate + (S)-methylmalonyl-CoA; High confidence in function and specificity. (510 aa)
PSM36_1820Acetyl/propionyl-CoA carboxylase, alpha subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (502 aa)
prsRibose-phosphate pyrophosphokinase; ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate; High confidence in function and specificity. (311 aa)
gcvPThe glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; High confidence in function and specificity; Belongs to the GcvP family. (950 aa)
fbaFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; High confidence in function and specificity. (330 aa)
PSM36_1936Cysteine synthase; O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate; High confidence in function and specificity. (315 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
PSM36_2015Sugar kinase of the NBD/HSP70 family; High confidence in function and specificity. (319 aa)
PSM36_2049Lactonase; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase and muconate cycloisomerase, which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold; High confidence in function and specificity. (394 aa)
pfkA36-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)
PSM36_2140MMCE, also called methylmalonyl-CoA racemase interconverts (2R)-methylmalonyl-CoA and (2S)-methylmalonyl-CoA. MMCE has been found in bacteria, archaea, and in animals. In eukaryotes, MMCE is an essential enzyme in a pathway that converts propionyl-CoA to succinyl-CoA, and is important in the breakdown of odd-chain length fatty acids, branched-chain amino acids, and other metabolites. In bacteria, MMCE participates in the reverse pathway for propionate fermentation, glyoxylate regeneration, and the biosynthesis of polyketide antibiotics. MMCE is closely related to glyoxalase I and type [...] (135 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (318 aa)
PSM36_2183This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide; High confidenc [...] (450 aa)
korA2-oxoglutarate oxidoreductase subunit KorA; Component of KG oxidoreductase (KOR) that catalyzes the CoA-dependent oxidative decarboxylation of 2-oxoglutarate (alpha-ketoglutarate, KG) to succinyl-CoA. Methyl viologen can act as electron acceptor in vitro; the physiologic electron acceptor is unknown. Is involved in the alternative TCA pathway that functions concurrently with fatty acid beta-oxidation. Since a growing body of evidence indicates that lipids (for example cholesterol and fatty acids) are a predominant growth substrate for M.tuberculosis during infection, flux through KOR l [...] (621 aa)
korB2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed; High confidence in function and specificity. (349 aa)
maeBBifunctional malic enzyme oxidoreductase/phosphotransacetylase; (S)-malate + NADP(+) <=> pyruvate + CO(2) + NADPH, Oxaloacetate <=> pyruvate + CO(2); High confidence in function and specificity. (767 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
acnAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (925 aa)
PSM36_2445This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide; High confidenc [...] (569 aa)
acoCDihydrolipoamide acetyltransferase; High confidence in function and specificity. (371 aa)
PSM36_2447Pyruvate dehydrogenase (acetyl-transferring); Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine <=> [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2); High confidence in function and specificity. (333 aa)
acoATPP-dependent pyruvate or acetoin dehydrogenase subunit alpha [Energy production and conversion]; High confidence in function and specificity. (330 aa)
mdh(S)-malate + NAD(+) <=> oxaloacetate + NADH; High confidence in function and specificity; Belongs to the LDH/MDH superfamily. (332 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa)
ptaAcetyl-CoA + phosphate = CoA + acetyl phosphate; High confidence in function and specificity. (337 aa)
PSM36_27493-hydroxyacyl-CoA dehydrogenase; S)-3-hydroxybutanoyl-CoA + NADP(+) <=> 3-acetoacetyl-CoA + NADPH; High confidence in function and specificity. (325 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (509 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (242 aa)
katACatalase; Hydrogen peroxide is produced as a consequence of oxidative cellular metabolism and can be converted to the highly reactive hydroxyl radical via transition metals, this radical being able to damage a wide variety of molecules within a cell, leading to oxidative stress and cell death. Catalases act to neutralise hydrogen peroxide toxicity, and are produced by all aerobic organisms ranging from bacteria to man. Most catalases are mono-functional, haem-containing enzymes, although there are also bifunctional haem-containing peroxidase/catalases that are closely related to plant [...] (502 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
PSM36_2950Putative serine O-acetyltransferase; Serine acetyltransferase [Amino acid transport and metabolism]; High confidence in function and specificity. (273 aa)
PSM36_2994Dihydrolipoamide succinyltransferase; Succinyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine <=> CoA + enzyme N(6)-(S-succinyldihydrolipoyl)lysine; High confidence in function and specificity. (449 aa)
odhA2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]; High confidence in function and specificity. (907 aa)
pgiGlucose-6-phosphate isomerase; D-glucose 6-phosphate = D-fructose 6-phosphate; High confidence in function and specificity; Belongs to the GPI family. (449 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
fumAFumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (546 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
PSM36_3199Sugar lactone lactonase YvrE; High confidence in function and specificity. (293 aa)
PSM36_3246This family consists of the succinate dehydrogenase subunit C of Bacillus subtilis, designated cytochrome b-558, and related sequences that include a fumarate reductase subunit C. This subfamily is only weakly; High confidence in function and specificity. (224 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Succinate + a quinone <=> fumarate + a quinol; High confidence in function and specificity. (647 aa)
PSM36_3248Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Succinate + a quinone <=> fumarate + a quinol; High confidence in function and specificity. (251 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa)
gnd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa)
PSM36_34182-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources; High confidence in function and specificity. (359 aa)
PSM36_34392-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources; High confidence in function and specificity. (345 aa)
PSM36_3440Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; High confidence in function and specificity. (259 aa)
PSM36_3467Sugar kinase; High confidence in function and specificity. (363 aa)
Your Current Organism:
Proteiniphilum saccharofermentans
NCBI taxonomy Id: 1642647
Other names: CECT 8610, DSM 28694, LMG 28299, LMG:28299, P. saccharofermentans, Proteiniphilum saccharofermentans Hahnke et al. 2016, Proteiniphilum sp. M3/6, strain M3/6
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