(30 nodes) Homologous DNA Pairing and Strand Exchange, and Checkpoint clamp complex network (Phytophthora ramorum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3G4Y9_PHYRM	Uncharacterized protein. (569 aa)
	H3G560_PHYRM	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (418 aa)
	H3G6X5_PHYRM	Uncharacterized protein. (352 aa)
	H3G7G4_PHYRM	HELICc2 domain-containing protein. (288 aa)
	H3G7Y5_PHYRM	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (628 aa)
	H3G8Y8_PHYRM	Uncharacterized protein; Belongs to the RecA family. (447 aa)
	H3GCB9_PHYRM	Replication protein A subunit. (622 aa)
	H3GED1_PHYRM	Uncharacterized protein. (332 aa)
	H3GER8_PHYRM	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (336 aa)
	H3GHW5_PHYRM	Helicase ATP-binding domain-containing protein. (1002 aa)
	H3GI82_PHYRM	Uncharacterized protein. (492 aa)
	H3GKR7_PHYRM	RECA_2 domain-containing protein. (798 aa)
	H3GLA8_PHYRM	Uncharacterized protein. (139 aa)
	H3GQI3_PHYRM	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (529 aa)
	H3GRD9_PHYRM	Uncharacterized protein. (290 aa)
	H3GV41_PHYRM	Uncharacterized protein. (1110 aa)
	H3GYU6_PHYRM	Helicase ATP-binding domain-containing protein. (256 aa)
	H3H137_PHYRM	Uncharacterized protein. (106 aa)
	H3H1R3_PHYRM	Uncharacterized protein. (691 aa)
	H3H3X3_PHYRM	Checkpoint protein; Belongs to the HUS1 family. (289 aa)
	H3H5C6_PHYRM	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (569 aa)
	H3H5N9_PHYRM	Uncharacterized protein. (408 aa)
	H3H7K0_PHYRM	3'-5' exonuclease domain-containing protein. (278 aa)
	H3HCJ7_PHYRM	Uncharacterized protein. (450 aa)
	H3HCX3_PHYRM	Uncharacterized protein. (381 aa)
	H3HCZ7_PHYRM	Uncharacterized protein. (531 aa)
	H3HDC0_PHYRM	Uncharacterized protein. (625 aa)
	H3HDP1_PHYRM	Uncharacterized protein. (226 aa)
	H3HDP3_PHYRM	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (840 aa)
	H3HE46_PHYRM	RECA_2 domain-containing protein. (401 aa)

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G4Y9_PHYRM	H3G560_PHYRM	H3G4Y9	H3G560	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.743
H3G4Y9_PHYRM	H3G6X5_PHYRM	H3G4Y9	H3G6X5	Uncharacterized protein.	Uncharacterized protein.	0.561
H3G4Y9_PHYRM	H3G7G4_PHYRM	H3G4Y9	H3G7G4	Uncharacterized protein.	HELICc2 domain-containing protein.	0.518
H3G4Y9_PHYRM	H3G7Y5_PHYRM	H3G4Y9	H3G7Y5	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.740
H3G4Y9_PHYRM	H3G8Y8_PHYRM	H3G4Y9	H3G8Y8	Uncharacterized protein.	Uncharacterized protein; Belongs to the RecA family.	0.900
H3G4Y9_PHYRM	H3GCB9_PHYRM	H3G4Y9	H3GCB9	Uncharacterized protein.	Replication protein A subunit.	0.696
H3G4Y9_PHYRM	H3GED1_PHYRM	H3G4Y9	H3GED1	Uncharacterized protein.	Uncharacterized protein.	0.458
H3G4Y9_PHYRM	H3GER8_PHYRM	H3G4Y9	H3GER8	Uncharacterized protein.	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.900
H3G4Y9_PHYRM	H3GHW5_PHYRM	H3G4Y9	H3GHW5	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.518
H3G4Y9_PHYRM	H3GI82_PHYRM	H3G4Y9	H3GI82	Uncharacterized protein.	Uncharacterized protein.	0.445
H3G4Y9_PHYRM	H3GKR7_PHYRM	H3G4Y9	H3GKR7	Uncharacterized protein.	RECA_2 domain-containing protein.	0.873
H3G4Y9_PHYRM	H3GLA8_PHYRM	H3G4Y9	H3GLA8	Uncharacterized protein.	Uncharacterized protein.	0.900
H3G4Y9_PHYRM	H3GQI3_PHYRM	H3G4Y9	H3GQI3	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.743
H3G4Y9_PHYRM	H3GRD9_PHYRM	H3G4Y9	H3GRD9	Uncharacterized protein.	Uncharacterized protein.	0.457
H3G4Y9_PHYRM	H3GV41_PHYRM	H3G4Y9	H3GV41	Uncharacterized protein.	Uncharacterized protein.	0.743
H3G4Y9_PHYRM	H3GYU6_PHYRM	H3G4Y9	H3GYU6	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.518
H3G4Y9_PHYRM	H3H137_PHYRM	H3G4Y9	H3H137	Uncharacterized protein.	Uncharacterized protein.	0.561
H3G4Y9_PHYRM	H3H3X3_PHYRM	H3G4Y9	H3H3X3	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.461
H3G4Y9_PHYRM	H3H5C6_PHYRM	H3G4Y9	H3H5C6	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.743
H3G4Y9_PHYRM	H3H5N9_PHYRM	H3G4Y9	H3H5N9	Uncharacterized protein.	Uncharacterized protein.	0.561

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