(24 nodes) Tricarboxylic acid cycle enzyme complex, and acetyl-CoA biosynthetic process from pyruvate network (Phytophthora ramorum)

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Your Input:
	H3G6Q4_PHYRM	Uncharacterized protein. (481 aa)
	H3G6Y6_PHYRM	Uncharacterized protein. (462 aa)
	H3G7C9_PHYRM	Transket_pyr domain-containing protein. (874 aa)
	H3G856_PHYRM	Transket_pyr domain-containing protein. (319 aa)
	H3G857_PHYRM	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (458 aa)
	H3G8Y4_PHYRM	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (406 aa)
	H3G928_PHYRM	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
	H3G957_PHYRM	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (318 aa)
	H3G9C6_PHYRM	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (444 aa)
	H3G9H1_PHYRM	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (438 aa)
	H3G9I6_PHYRM	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (361 aa)
	H3G9I7_PHYRM	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (419 aa)
	H3G9W6_PHYRM	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (784 aa)
	H3GA90_PHYRM	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (422 aa)
	H3GAB7_PHYRM	Transket_pyr domain-containing protein. (1020 aa)
	H3GAL9_PHYRM	Dihydrolipoyl dehydrogenase. (499 aa)
	H3GBQ9_PHYRM	Uncharacterized protein. (100 aa)
	H3GE36_PHYRM	Uncharacterized protein. (551 aa)
	H3GHJ1_PHYRM	Uncharacterized protein. (113 aa)
	H3GTW5_PHYRM	ATP-grasp domain-containing protein. (312 aa)
	H3GV23_PHYRM	Lipoyl-binding domain-containing protein. (273 aa)
	H3GZV6_PHYRM	Uncharacterized protein. (1057 aa)
	H3H3D6_PHYRM	Uncharacterized protein. (697 aa)
	H3HAP3_PHYRM	Lipoyl-binding domain-containing protein. (215 aa)

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G6Q4_PHYRM	H3G6Y6_PHYRM	H3G6Q4	H3G6Y6	Uncharacterized protein.	Uncharacterized protein.	0.962
H3G6Q4_PHYRM	H3G7C9_PHYRM	H3G6Q4	H3G7C9	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.903
H3G6Q4_PHYRM	H3G856_PHYRM	H3G6Q4	H3G856	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.942
H3G6Q4_PHYRM	H3G857_PHYRM	H3G6Q4	H3G857	Uncharacterized protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.958
H3G6Q4_PHYRM	H3G8Y4_PHYRM	H3G6Q4	H3G8Y4	Uncharacterized protein.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.958
H3G6Q4_PHYRM	H3G928_PHYRM	H3G6Q4	H3G928	Uncharacterized protein.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.982
H3G6Q4_PHYRM	H3G957_PHYRM	H3G6Q4	H3G957	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.818
H3G6Q4_PHYRM	H3G9C6_PHYRM	H3G6Q4	H3G9C6	Uncharacterized protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.960
H3G6Q4_PHYRM	H3G9H1_PHYRM	H3G6Q4	H3G9H1	Uncharacterized protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.899
H3G6Q4_PHYRM	H3G9I6_PHYRM	H3G6Q4	H3G9I6	Uncharacterized protein.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.715
H3G6Q4_PHYRM	H3G9I7_PHYRM	H3G6Q4	H3G9I7	Uncharacterized protein.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.658
H3G6Q4_PHYRM	H3GA90_PHYRM	H3G6Q4	H3GA90	Uncharacterized protein.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.658
H3G6Q4_PHYRM	H3GAB7_PHYRM	H3G6Q4	H3GAB7	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.903
H3G6Q4_PHYRM	H3GBQ9_PHYRM	H3G6Q4	H3GBQ9	Uncharacterized protein.	Uncharacterized protein.	0.939
H3G6Q4_PHYRM	H3GHJ1_PHYRM	H3G6Q4	H3GHJ1	Uncharacterized protein.	Uncharacterized protein.	0.903
H3G6Q4_PHYRM	H3GTW5_PHYRM	H3G6Q4	H3GTW5	Uncharacterized protein.	ATP-grasp domain-containing protein.	0.922
H3G6Q4_PHYRM	H3GV23_PHYRM	H3G6Q4	H3GV23	Uncharacterized protein.	Lipoyl-binding domain-containing protein.	0.939
H3G6Q4_PHYRM	H3GZV6_PHYRM	H3G6Q4	H3GZV6	Uncharacterized protein.	Uncharacterized protein.	0.960
H3G6Q4_PHYRM	H3HAP3_PHYRM	H3G6Q4	H3HAP3	Uncharacterized protein.	Lipoyl-binding domain-containing protein.	0.939
H3G6Y6_PHYRM	H3G6Q4_PHYRM	H3G6Y6	H3G6Q4	Uncharacterized protein.	Uncharacterized protein.	0.962

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