(31 nodes) Anaphase-promoting complex, and Spindle checkpoint signaling network (Phytophthora ramorum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	H3G5C0_PHYRM	TPR_REGION domain-containing protein. (476 aa)
	H3G642_PHYRM	WD_REPEATS_REGION domain-containing protein. (319 aa)
	H3G666_PHYRM	RING-type domain-containing protein. (87 aa)
	H3G782_PHYRM	WD_REPEATS_REGION domain-containing protein. (318 aa)
	H3G795_PHYRM	Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (958 aa)
	H3GAB6_PHYRM	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (274 aa)
	H3GBF3_PHYRM	CYCLIN domain-containing protein; Belongs to the cyclin family. (358 aa)
	H3GBI8_PHYRM	Uncharacterized protein. (495 aa)
	H3GCL4_PHYRM	Uncharacterized protein. (727 aa)
	H3GFD8_PHYRM	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (475 aa)
	H3GFI3_PHYRM	Uncharacterized protein. (513 aa)
	H3GHC7_PHYRM	Uncharacterized protein. (308 aa)
	H3GJ76_PHYRM	TPR_REGION domain-containing protein. (273 aa)
	H3GK52_PHYRM	Uncharacterized protein. (414 aa)
	H3GL68_PHYRM	WD_REPEATS_REGION domain-containing protein. (537 aa)
	H3GLW2_PHYRM	CULLIN_2 domain-containing protein; Belongs to the cullin family. (689 aa)
	H3GSZ7_PHYRM	Serine/threonine-protein kinase PLK. (792 aa)
	H3GTK7_PHYRM	Uncharacterized protein. (655 aa)
	H3GTU8_PHYRM	Uncharacterized protein. (414 aa)
	H3GUJ3_PHYRM	Uncharacterized protein. (330 aa)
	H3GWS0_PHYRM	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (179 aa)
	H3GYX6_PHYRM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (242 aa)
	H3H233_PHYRM	Uncharacterized protein. (142 aa)
	H3H5C5_PHYRM	Uncharacterized protein. (1926 aa)
	H3H8H1_PHYRM	Uncharacterized protein. (1091 aa)
	H3H9A0_PHYRM	Uncharacterized protein. (1175 aa)
	H3HB82_PHYRM	HORMA domain-containing protein. (200 aa)
	H3HBQ8_PHYRM	Uncharacterized protein. (134 aa)
	H3HD13_PHYRM	Protein kinase domain-containing protein. (612 aa)
	H3HD97_PHYRM	Uncharacterized protein. (167 aa)
	H3HDX0_PHYRM	BUB1 N-terminal domain-containing protein. (550 aa)

Your Current Organism:

Phytophthora ramorum

NCBI taxonomy Id: 164328
Other names: BBA 9/95, CBS 101553, CPHST BL 55G, Ex-type CPHST BL 55G, P. ramorum, Phytophthora sp. ex Parrotia persica, Sudden oak death agent, WPC P10103, ramorum blight, sudden oak death

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3G5C0_PHYRM	H3G642_PHYRM	H3G5C0	H3G642	TPR_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.932
H3G5C0_PHYRM	H3G666_PHYRM	H3G5C0	H3G666	TPR_REGION domain-containing protein.	RING-type domain-containing protein.	0.999
H3G5C0_PHYRM	H3G782_PHYRM	H3G5C0	H3G782	TPR_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.961
H3G5C0_PHYRM	H3GAB6_PHYRM	H3G5C0	H3GAB6	TPR_REGION domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.622
H3G5C0_PHYRM	H3GBF3_PHYRM	H3G5C0	H3GBF3	TPR_REGION domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.717
H3G5C0_PHYRM	H3GBI8_PHYRM	H3G5C0	H3GBI8	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.919
H3G5C0_PHYRM	H3GCL4_PHYRM	H3G5C0	H3GCL4	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.740
H3G5C0_PHYRM	H3GFD8_PHYRM	H3G5C0	H3GFD8	TPR_REGION domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.744
H3G5C0_PHYRM	H3GFI3_PHYRM	H3G5C0	H3GFI3	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.744
H3G5C0_PHYRM	H3GHC7_PHYRM	H3G5C0	H3GHC7	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.999
H3G5C0_PHYRM	H3GJ76_PHYRM	H3G5C0	H3GJ76	TPR_REGION domain-containing protein.	TPR_REGION domain-containing protein.	0.949
H3G5C0_PHYRM	H3GK52_PHYRM	H3G5C0	H3GK52	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.999
H3G5C0_PHYRM	H3GL68_PHYRM	H3G5C0	H3GL68	TPR_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.961
H3G5C0_PHYRM	H3GLW2_PHYRM	H3G5C0	H3GLW2	TPR_REGION domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.999
H3G5C0_PHYRM	H3GSZ7_PHYRM	H3G5C0	H3GSZ7	TPR_REGION domain-containing protein.	Serine/threonine-protein kinase PLK.	0.787
H3G5C0_PHYRM	H3GTK7_PHYRM	H3G5C0	H3GTK7	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.994
H3G5C0_PHYRM	H3GTU8_PHYRM	H3G5C0	H3GTU8	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.999
H3G5C0_PHYRM	H3GUJ3_PHYRM	H3G5C0	H3GUJ3	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.977
H3G5C0_PHYRM	H3GWS0_PHYRM	H3G5C0	H3GWS0	TPR_REGION domain-containing protein.	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	0.989
H3G5C0_PHYRM	H3GYX6_PHYRM	H3G5C0	H3GYX6	TPR_REGION domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.997

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